Results 31 to 40 of about 611 (156)

Efficacy of a short-acting oral fluralaner formulation (WellPet™) against fleas and brown dog ticks in controlled and field conditions [PDF]

Frontiers in Veterinary Science
BackgroundFluralaner is an isoxazoline widely used for flea and tick control in dogs, mainly in long-acting formulations. However, the performance of short-acting, lower-dose options remains unexplored in scientific literature.
Isabelle Vilela Bonfim, Breno Cayeiro Cruz, Igor Renan Honorato Gatto, Debora Azevedo Borges, Monique Taveira Medeiros, Gessica Ariane de Melo Cruz, Juliana Aparecida do Carmo Emidio Moreira da Silva, Clara Rodrigues Dutra, Carlos Eduardo Marques de Oliveira Filho, Ygor Henrique da Silva, Brena Gava Guimarães, Marcus Antonio Martins Buso, Ferdinando Nielsen de Almeida, Thais Ribeiro Correia, Fabio Barbour Scott, Diefrey Ribeiro Campos   +15 more
doaj   +2 more sources

Efficacy of a fluralaner-based ectoparasiticide for the control of otodectic and sarcoptic mange in naturally infested dogs, evaluated in randomized, double-blind clinical studies [PDF]

Parasites & Vectors
Background One of the most relevant parasitic mites is Sarcoptes scabiei, which causes sarcoptic mange, commonly known as scabies. This condition is highly contagious and leads to intense itching and skin lesions in dogs. Otodectes cynotis, the “ear mite,
Breno Cayeiro Cruz, Marina Belucci Teixeira, Gessica Ariane de Melo Cruz, Juliana Aparecida do Carmo Emidio Moreira da Silva, Milenni Garcia Michels, Carol Della Nina Pistoni, Marcus Antonio Martins Buso, Ferdinando Nielsen de Almeida, Igor Renan Honorato Gatto   +8 more
doaj   +2 more sources

Simparica Trio® kills Ctenocephalides felis on dogs and provides month-long protection against the transmission of Dipylidium caninum [PDF]

Parasites & Vectors
Background The cestode Dipylidium caninum is known to infect dogs via the ingestion of an intermediate flea host, typically Ctenocephalides felis. Simparica Trio® is an oral combination drug product for dogs effective in the treatment and prevention of ...
Lindsay Weaver, Alta Viljoen, Riaan Maree, Lina D’Hanis, Shelby Jones, Jane Tonso, Reinier Zwiegers, Julian Liebenberg, Sean Mahabir, Keith Baker, Jessica Rodriguez, Chris Adolph, Thomas Geurden   +12 more
doaj   +2 more sources

Design and synthesis of sarolaner, a novel, once-a-month, oral isoxazoline for the control of fleas and ticks on dogs

Bioorganic & Medicinal Chemistry Letters, 2016
Over the last decade, the isoxazoline motif has become the intense focus of crop protection and animal health companies in their search for novel pesticides and ectoparasiticides. Herein we report the discovery of sarolaner, a proprietary, optimized-for-animal health use isoxazoline, for once-a-month oral treatment of flea and tick infestation on dogs.
Curtis, Michael P., Vaillancourt, Valerie, Goodwin, Richard M., Chubb, Nathan A. L., Howson, William, McTier, Tom L., Pullins, Aleah, Zinser, Erich W., Meeus, Patrick F. M., Woods, Debra J., Hedges, Laura, Stuk, Tim, Price, Jeffrey E., Koch, Jason D., Menon, Sanjay R.   +14 more
openaire   +4 more sources

Efficacy of Simparica Trio® against induced infections of Ancylostoma braziliense and Ancylostoma ceylanicum in dogs [PDF]

Parasites & Vectors
Background Hookworm infections such as Ancylostoma braziliense and A. ceylanicum pose a significant threat to pets and are implicated in causing zoonotic diseases. Despite the availability of preventatives, compliance can be lacking. Increasing pet owner
Raj Packianathan, Andrew Hodge, Natalie Bruellke, Michael Pearce, Frans Selepe, Piyanan Taweethavonsawat, Thomas Geurden   +6 more
doaj   +2 more sources

Clinical efficacy and parasitological responses to selamectinâ€"sarolaner combination therapy for Notoedric Mange in cats: A prospective case series from Yogyakarta city, Indonesia

Open Veterinary Journal
Background: Feline Mange caused by Notoedres cati requires a safe, suitable, and effective therapy. Aim: This study aimed to describe the clinical and parasitological findings of naturally occurring Notoedric Mange in cats in Yogyakarta City ...
Lily Gunawan, Soedarmanto Indarjulianto, Raden Wisnu Nurcahyo, Agustina Dwi Wijayanti, Ridha Avicena Ila Salsabila, Cahyo Wibisono, Luh Made Sudimartini, Nine Dwindadari Meyana, Deswandi Welhelmus Saputra Berri, Jesica Gloria Soerinta   +9 more
doaj   +2 more sources

Field safety and efficacy of an orally administered combination of sarolaner, moxidectin and pyrantel (Simparica Trio®) for the prevention of angiostrongylosis in dogs presented as veterinary patients [PDF]

Parasites & Vectors, 2020
Background Infection with the cardiopulmonary nematode Angiostrongylus vasorum may cause severe disease in dogs, therefore prophylactic treatments are necessary to prevent infection in dogs at risk. A clinical field study was conducted to demonstrate the
Csilla Becskei, Jakob L. Willesen, Manuela Schnyder, Magda Wozniakiewicz, Nataliya Miroshnikova, Sean P. Mahabir   +5 more
doaj   +2 more sources

Field efficacy and safety evaluation of a novel chewable tablet (Credelio Quattro™) containing lotilaner, moxidectin, praziquantel, and pyrantel against gastrointestinal nematode infections in dogs in the USA [PDF]

Parasites & Vectors
Background Gastrointestinal nematodes such as hookworms (Ancylostoma caninum) and roundworms (Toxocara canis) commonly infect dogs and are zoonotic parasites capable of producing clinical disease in humans.
Samuel Charles, Scott Wiseman, Molly D. Savadelis, Eric Nichols, Lisa Young   +4 more
doaj   +2 more sources

Efficacy of a novel oral chewable tablet containing sarolaner, moxidectin and pyrantel (Simparica Trio™) against natural flea and tick infestations on dogs presented as veterinary patients in Europe

Parasites & Vectors, 2020
Background A novel chewable oral tablet containing sarolaner, moxidectin and pyrantel (Simparica Trio™) has recently been developed to provide persistent protection against flea and tick infections for a month, treatment of hookworm and roundworm ...
Csilla Becskei, Daphne Fias, Sean P. Mahabir, Robert Farkas   +3 more
doaj   +2 more sources

Evaluation of the efficacy of Simparica Trio® in the prevention of the transmission of Babesia canis by infected Dermacentor reticulatus to dogs [PDF]

Parasites & Vectors
Background Babesia canis is a clinically relevant vector-borne pathogen in dogs, and its presence is expanding. The efficacy of Simparica Trio® (Zoetis) in the prevention of B. canis transmission was evaluated at the minimum recommended label dose of 1.2 
Stasia Borowski, Alta Viljoen, Lina D’Hanis, Sean Mahabir, Thomas Geurden   +4 more
doaj   +2 more sources