Results 131 to 140 of about 99,522,423 (293)

Aspergillus fumigatus secretes a protease(s) that displays in silico binding affinity towards the SARS-CoV-2 spike protein and mediates SARS-CoV-2 pseudovirion entry into HEK-293T cells

Virology Journal
Background The novel coronavirus disease of 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Data from the COVID-19 clinical control case studies showed that this disease could also manifest
Nozethu Mjokane, Eric O. Akintemi, Saheed Sabiu, Onele M. N. Gcilitshana, Jacobus Albertyn, Carolina H. Pohl, Olihile M. Sebolai   +6 more
doaj   +1 more source

Neutralization of SARS-CoV-2 spike pseudotyped virus by recombinant ACE2-Ig

Nature Communications, 2020
SARS-CoV-2 uses ACE2 as the entry receptor. Here, the authors show that an ACE2-Ig fusion protein inhibits entry of virus pseudotyped with the SARS-CoV-2 spike protein, show differential binding kinetics of SARS-CoV and SARSCoV-2 spike proteins to ACE2 ...
Changhai Lei, Kewen Qian, Tian Li, Sheng Zhang, Wenyan Fu, Min Ding, Shi Hu   +6 more
doaj   +1 more source

Clinical performance of Fluorecare SARS-CoV-2 Spike Protein Test Kit according to RT-PCR assays.

, 2022
Clinical performance of Fluorecare SARS-CoV-2 Spike Protein Test Kit according to RT-PCR assays.
Laura Cardarelli (11944176), Paola Marin (11944182), Annamaria Davini (11944173), Valentina Tonelotto (11944170), Milena Calderone (11944179)   +4 more
core   +1 more source

Dilution protocol for anti-SARS-CoV-2 spike protein immunoassay, implemented October 12, 2022.

Dilution protocol for anti-SARS-CoV-2 spike protein immunoassay, implemented October 12, 2022.
Stephen J. Pont (18271974), Michael D. Swartz (10139250), Jessica A. Ross (13767868), Mark A. Silberman (18271977), Micaela N. Sandoval (18260239), Eric Boerwinkle (36288), Samuel P. McClellan (18271971)   +6 more
core   +1 more source

Mutational landscape of SARS-CoV-2 Spike protein VOC and VOI based on the WHO label.

, 2022
Mutational landscape of SARS-CoV-2 Spike protein VOC and VOI based on the WHO label.
Carla Torres Braconi (12621702), Ricardo Durães-Carvalho (6798008), Danilo Rosa Nunes (12621699), Clarice Weis Arns (3207828), Louisa F. Ludwig-Begall (10826467)   +4 more
core   +1 more source

Cdc42 improve SARS-CoV-2 spike protein-induced cellular senescence through activating of Wnt/β-Catenin signaling pathway

Frontiers in Cellular and Infection Microbiology
IntroductionSARS-CoV-2 infection drove senescent cells and the senescence-associated phenotypes were reported playing roles in disease progression, which contributes to severe COVID-19 and related sequelae. Cdc42 is involved in the regulation of cellular
Chunmei Nong, Chunmei Nong, Chunmei Nong, Zhenzhen Wu, Chan Yang, Wei Xu, Linyi Luo, Jianping Zhou, Lihan Shen, Yinghua Chen, Yinghua Chen, Yaoqin Yuan, Guodong Hu, Guodong Hu, Guodong Hu   +14 more
doaj   +1 more source

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source

Differences in SARS‐CoV‐2 Antigen Persistence in Individuals With Systemic Autoimmune Rheumatic Diseases Compared to the General Population: A RECOVER‐Adult Cohort Study

Arthritis &Rheumatology, EarlyView.
Objective Individuals with systemic autoimmune rheumatic diseases (SARDs) are at risk for worse acute and post–acute COVID‐19 outcomes, though whether individuals with SARDs have longer persistence of viral antigens after COVID‐19 has not been studied.
Naomi J. Patel, Zoe Swank, Jiaqi Wang, Xiaosong Wang, Lauren A. O'Keeffe, Madison Negron, Liya S. Getachew, Louise L. Hansen, Grace Qian, Alene A. Saavedra, Kevin T. Mueller, Natalie A. Davis, Kathleen M. M. Vanni, Sandria Savage, Julie S. Lam, Zachary S. Wallace, David R. Walt, Jeffrey A. Sparks, on behalf of RECOVER‐Adult   +18 more
wiley   +1 more source

SARS CoV-2 SPIKE GLYCOPROTEIN MUTATIONS AND CHANGES IN PROTEIN STRUCTURE

Trakya University Journal of Natural Sciences, 2021
Severe Acute Respiratory Syndrome Corona Virus-2 (SARS CoV-2) is a single-stranded positive polarity RNA virus with a high virulence effect. Spike (S) glycoprotein is the outermost component of the SARS CoV-2 virion and is important in the entry of the virus into the cell via the angiotensin converting enzyme 2 (ACE2) receptor.
openaire   +6 more sources

Dose‐related propofol resistance in COVID‐19 patients: Altered drug plasma levels, mechanistic insights from neuronal‐derived extracellular vesicles and miRNA analysis

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Critical care for COVID‐19 patients presents unique challenges, particularly in sedation management. Patients demonstrate notable dose‐related resistance to propofol, potentially due to complex pharmacokinetic alterations. Emerging evidence suggests that plasma extracellular vesicle‐associated miRNA represents valuable predictive ...
Debora Curci, Carlotta Bidoli, Marco Gerdol, Charisse Winston, Robert A. Rissman, Giuliana Decorti, Antonella Fabretto, Andrea Taddio, Gabriele Stocco, Erik Roman‐Pognuz, Marianna Lucafò   +10 more
wiley   +1 more source