Results 161 to 170 of about 25,548 (305)

Proteomic Profiling of Myofiber Repair Annexins and Their Role in Duchenne Muscular Dystrophy

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Myofiber regeneration and membrane repair play crucial roles in maintaining the continuous physiological functioning of the neuromuscular system. A swift and efficient repair mechanism enables the rapid restoration of sarcolemmal integrity following cellular impairment in damaged skeletal muscles.
Paul Dowling   +6 more
wiley   +1 more source

Muscle fatigue in patients with severe long COVID: A 2‐year follow‐up study

open access: yesPM&R, EarlyView.
Abstract Background Fatigue is recognized as one of the most persistent and debilitating symptoms of long COVID, affecting both functionality and quality of life. However, its long‐term effects, especially beyond the first year after infection, remain poorly understood.
Isabella da Silva Almeida   +6 more
wiley   +1 more source

Machine learning‐driven advances in carbon‐based quantum dots: Opportunities accompanied by challenges

open access: yesResponsive Materials, EarlyView.
Machine learning provides a unifying framework to connect structure, fluorescence properties, and applications of carbon‐based quantum dots. This review highlights how data‐driven strategies enable fluorescence regulation, reveal underlying mechanisms, and accelerate the rational design of functional carbon dots.
Liangfeng Chen   +8 more
wiley   +1 more source

Antimicrobial Residues in a Key Cerrado River: Distribution, Persistence, and Effects on Zebrafish Embryo‐Larval Development

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT The current study aimed to quantify the antimicrobials amoxicillin (AMX), cefazolin (CFZ), chloramphenicol (CHL), metronidazole (MTZ), and sulfamethoxazole (SX) in effluents and surface water of an important Cerrado river, calculate their half‐lives, and analyze their ecotoxicity following single and combined exposures.
Náthala Maria Simão   +12 more
wiley   +1 more source

Staging concept for aging management: Definition, mechanism, and coping strategies

open access: yesVIEW, EarlyView.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang   +6 more
wiley   +1 more source

Convergent digestive adaptation to resource limitation in an insular lizard across a microgeographic archipelago

open access: yesJournal of Animal Ecology, EarlyView.
Replicated mainland–islet populations of the Skyros wall lizard reveal consistent divergence in digestive physiology, including gut morphology, passage time, digestive efficiency and enzyme activity. These results show how ecological variation in resource availability can shape digestive performance across populations in insular environments.
Aikaterini Reppa   +8 more
wiley   +1 more source

Embryonic temperature and the genes regulating myogenesis in teleosts

open access: yes, 2008
In this study, full coding sequences of Atlantic salmon (Salmo salar L.) muscle genes were cloned, including myogenic regulatory factors (MRFs) (myod1c, myog, mrf4, myf5), inhibitors of Myostatin (fst, decorin), markers of myogenic progenitor cell (MPC ...
Macqueen, Daniel J.
core  

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

open access: yesAndrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Are sex hormone deficiency and skeletal muscle decline related? Exploring the regulation of satellite cells and protein synthesis in menopause

open access: yes
The menopause is characterised by a marked reduction in ovarian sex hormones –oestradiol (E2) and progesterone. This hormonal decline has been purported to be associated with reductions in skeletal muscle mass and strength observed during the menopausal ...
Hanquet, Marion   +4 more
core   +1 more source

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