Results 191 to 200 of about 120,121 (346)

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

Andrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Amylin analogues as a novel perspective in anti‐obesity therapy

British Journal of Pharmacology, EarlyView.
Abstract Public health systems face a major challenge because of the worldwide obesity epidemic. The number of obese individuals has increased dramatically and, even in Switzerland which may be considered a relatively “lean” country, the numbers are alarmingly high and have reached almost 50% of the adult population.
Thomas A. Lutz
wiley   +1 more source

Renalase knockdown inhibits proliferation of mouse satellite cells. [PDF]

Mol Biol Rep
Kato Y, Tokinoya K, Aoki K, Takekoshi K.
europepmc   +1 more source

Physiological Basis of Sex Differences in Human Performance and Exercise‐Associated Pathology

Clinical Endocrinology, EarlyView.
ABSTRACT The presence of sex differences in human physical performance is well‐established and shaped by distinct endocrine, anatomical and physiological mechanisms. Despite sustained advances, our understanding of how inherent biological factors drive variations in exercise capacity and related pathologies is still developing.
David A. Holdsworth, Thomas J. O'Leary, Craig L. Doig, Natalie Taylor, Jasminder Dosanjh, David R. Woods, Michael J. Stacey, Robert M. Gifford   +7 more
wiley   +1 more source

Dual Roles of Adipose Tissue in Skeletal Muscle Regeneration: Pro-Regenerative Versus Maladaptive. [PDF]

J Cachexia Sarcopenia Muscle
Lu C, Lu F, Cai J.
europepmc   +1 more source

Activation of satellite cells and the regeneration of human skeletal muscle are expedited by ingestion of nonsteroidal anti‐inflammatory medication

The FASEB Journal, 2016
A. Mackey, Lotte K. Rasmussen, F. Kadi, P. Schjerling, I. C. Helmark, E. Ponsot, P. Aagaard, J. Durigan, M. Kjaer   +8 more
semanticscholar   +1 more source

Decadal Rapid Change in Energetic Carrying Capacity for Juvenile Chum Salmon in the Sanriku Coast

Fisheries Oceanography, EarlyView.
ABSTRACT Adult returns to coastal rivers in Sanriku, located near the southernmost area of chum salmon distribution, have declined since 2010. Climate‐induced fluctuations in juvenile prey availability may affect growth and survival, which are linked to adult returns.
Yuki Iino, Yuichi Shimizu, Tomoki Sato, Takashi Kitagawa   +3 more
wiley   +1 more source

Does Time Tick Faster in Cerebral Palsy? Accelerated Aging as a Framework for Skeletal Muscle Dysfunction. [PDF]

FASEB J
Horwath O, Edman S, Dayanidhi S, Englund D, Peterson MD, von Walden F.   +5 more
europepmc   +1 more source

Satellite cells and skeletal muscle regeneration

Journal of British Surgery, 1966
J C T Church, R F X Noronha, D B Allbrook   +2 more
openaire   +1 more source