Results 221 to 230 of about 25,548 (305)

Divergent skeletal muscle metabolite exchange in insulin‐like growth factor‐1‐stimulated myotubes and resistance‐exercised human muscle

Experimental Physiology, EarlyView.
Abstract Skeletal muscle hypertrophy requires a substantial nutrient influx for biomass accretion, but global metabolite exchange during growth is poorly characterized. Therefore, we profiled the metabolite uptake and release in insulin‐like growth factor‐1 (IGF‐1)‐stimulated C2C12 myotubes and human muscle 24 h after resistance exercise ...
Tim Havers, Moritz Eggelbusch, Marius Meinhold, Kira Sing, Rainer Okrojek, Anna Artati, Michael Witting, Dominik Lutter, Claire V. Kieker, Collin Starke, Tushar More, Karsten Hiller, Flemming Dela, Martin Schönfelder, André Kafka, Stephan Geisler, Henning Wackerhage   +16 more
wiley   +1 more source

Emerging roles of epigenetics in the pathogenesis of sarcopenia. [PDF]

Epigenomics
Wu M, Zhao Y, Gu S, Lu H, Cha Y, Yang Y, Yang Q, Yang L, Xiao Z.   +8 more
europepmc   +1 more source

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source

mRNA splicing in turkey muscle satellite cells is dynamically altered upon thermal challenge. [PDF]

PLoS One
Powell AA, Strasburg GM, Velleman SG, Reed KM.   +3 more
europepmc   +1 more source

To Mars through LEO: How commercial space travel will change exploration‐enabling research

Experimental Physiology, EarlyView.
Christopher Puhl, Michail Magkos
wiley   +1 more source

Intramuscular pathways of maladaptation in overtraining syndrome

The Journal of Physiology, EarlyView.
Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter, Oscar Horwath, Sabrina Tzivia Barsky, Ferdinand von Walden, Johanna T. Lanner   +4 more
wiley   +1 more source

Biomimetic Scaffolds and Extracellular Matrix-Based Strategies for Myofiber Regeneration in Volumetric Muscle Loss. [PDF]

Drug Des Devel Ther
Pandey GA, Kashikar PM, Nathani K, Mangrulkar S, Sawarkar SP, Omri A.   +5 more
europepmc   +1 more source

Angiotensin‐converting enzyme and exercise adaptations: Genetic variability, pharmacological modulation and future directions

The Journal of Physiology, EarlyView.
Abstract figure legend ACE I/D genotype, enzyme activity and integrated physiological adaptations. Upper panel: Conceptual framework linking the ACE I/D polymorphism (left) with circulating/tissue ACE activity (centre; violin plots based on hypothetical data for illustration) and strength/power versus endurance phenotypes (right).
Tórur Sjúrðarson, Nikolai B. Nordsborg   +1 more
wiley   +1 more source

Transcriptome Analysis of miRNAs Involved in the Myogenic Differentiation of Goat Skeletal Muscle Satellite Cells. [PDF]

Cells
Luo R, Zhong T, Wang L, Yang S, Li L, Zhang H, Zhan S.   +6 more
europepmc   +1 more source

Decoding the space integrome: Personalized countermeasures for a mission to Mars

Experimental Physiology, EarlyView.
Damian M. Bailey
wiley   +1 more source