Results 101 to 110 of about 2,049,707 (290)

Targeting p21‐High Senescent Kupffer Cells Nanotherapeutically Potentiates Antitumor Immunity in Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombus

open access: yesAdvanced Science, EarlyView.
Schematic illustration of a biomimetic SKEV@AAV platform targeting p21‐high senescent Kupffer cells (sKCs) in hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT). p21‐high sKCs accumulate in the PVTT microenvironment and establish an immunosuppressive, SASP‐rich environment that facilitates tumor cell proliferation and immune evasion.
Na Ta   +10 more
wiley   +1 more source

Comparison of DNA methylation levels of repetitive loci during bovine development

open access: yesBMC Proceedings, 2011
Background DNA methylation of cytosine residues in CpG dinucleotide controls gene expression and dramatically changes during development. Its pattern is disrupted in cloned animals suggesting incomplete reprogramming during somatic cell nuclear transfer (
Kaneda Masahiro   +3 more
doaj   +1 more source

Chromosomal distribution of the As51 satellite DNA in two species complexes of the genus Astyanax (Pisces, Characidae)

open access: yesGenetics and Molecular Biology, 2006
The chromosomal localization of the As51 satellite DNA was identified by fluorescent in situ hybridization (FISH) in specimens of the characid fish Astyanax scabripinnis and Astyanax fasciatus, which are considered species complexes because of their ...
Luciano Douglas dos Santos Abel   +2 more
doaj   +1 more source

An Immediate‐Response Detection System for γ‐Hydroxybutyrate to Enhance Personal Safety in Social Environments

open access: yesAdvanced Science, EarlyView.
A graphene‐based electrical biosensor enables rapid and highly sensitive detection of GHB at 100 fm in both standard solutions and artificial urine, providing reliable point‐of‐need screening for drug‐facilitated sexual assault. The platform demonstrates strong selectivity, fast response, and a wide dynamic range, supporting accurate detection in ...
Jai Eun An   +8 more
wiley   +1 more source

Performance Assessment using ACM in DVB-S2/Advanced DVB-RCS Satellite Systems [PDF]

open access: yes, 2009
This paper presents the benefits of using adaptive coding and modulation in DVB-S2/advanced DVB-RCS satellite systems. The results are based on a satellite system simulator which was developed during an ESA study.
Boussemart, Vincent   +3 more
core   +1 more source

Psychological Stress Associated Bile Acid Reprogramming Promotes Hepatocellular Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng   +10 more
wiley   +1 more source

Origins and Evolutionary Patterns of the 1.688 Satellite DNA Family in Drosophila Phylogeny

open access: yesG3: Genes, Genomes, Genetics, 2020
Leonardo G. de Lima   +2 more
doaj   +1 more source

DNA-directed self-assembly of core-satellite plasmonic nanostructures: a highly sensitive and reproducible near-IR SERS sensor

open access: yes, 2013
DNA-directed self-assembly of core-satellite plasmonic nanostructures: a highly sensitive and reproducible near-IR SERS ...
P Reineck (13446981)   +5 more
core  

On the role of satellite communications for emergency situations with a focus on Europe [PDF]

open access: yes, 2011
International audienceIn this paper, we describe how satellite communications may contribute to disaster management. During emergency situations, satellite communications present many advantages in supporting or replacing a terrestrial infrastructure (if
Matteo Berioli   +14 more
core   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

open access: yesAdvanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha   +4 more
wiley   +1 more source

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