Results 41 to 50 of about 142,521 (283)
Structural basis for DNMT3A-mediated de novo DNA methylation. [PDF]
, 2018 DNA methylation by de novo DNA methyltransferases 3A (DNMT3A) and 3B (DNMT3B) at cytosines is essential for genome regulation and development. Dysregulation of this process is implicated in various diseases, notably cancer.
Chen, Dongliang +11 more
core +2 more sources
Stem Cell Research, 2014 The loss of genome integrity in adult stem cells results in accelerated tissue aging and is possibly cancerogenic. Adult stem cells in different tissues appear to react robustly to DNA damage.
Leyla Vahidi Ferdousi +7 more
doaj +1 more source
A recombinant DNA‐satellite associated with Pepper yellow leaf curl Indonesia virus in highland area
Indonesian Journal of Biotechnology, 2021 Yellow curl disease caused by begomovirus is a major threat for horticulture in Indonesia. Control mea‐ sures for the disease face several constraints, one of which is the association between begomovirus and DNA satellites which can affect the severity ...
Argawi Kandito +3 more
doaj +1 more source
A conserved function for pericentromeric satellite DNA
eLife, 2018 A universal and unquestioned characteristic of eukaryotic cells is that the genome is divided into multiple chromosomes and encapsulated in a single nucleus. However, the underlying mechanism to ensure such a configuration is unknown.
Madhav Jagannathan +2 more
doaj +1 more source
DNMTs are required for delayed genome instability caused by radiation [PDF]
, 2012 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited ...
Anderson, RM +10 more
core +2 more sources
Genetics and Molecular Biology, 2008 We characterized sequences of a novel SSS139 RsaI satellite DNA family in Drosophila gouveai and Drosophila seriema, two members of the Drosophila buzzatii cluster (D. repleta group).
Fernando F. Franco +2 more
doaj +1 more source
Virus satellites drive viral evolution and ecology [PDF]
, 2015 Virus satellites are widespread subcellular entities, present both in eukaryotic and in prokaryotic cells. Their modus vivendi involves parasitism of the life cycle of their inducing helper viruses, which assures their transmission to a new host. However,
Buckling, Angus +8 more
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
PLoS ONE, 2013 The performance of adult stem cells is crucial for tissue homeostasis but their regenerative capacity declines with age, leading to failure of multiple organs.
Wendy Cousin +7 more
doaj +1 more source
Circular DNA's from HeLa cell nuclei and mitochondria [PDF]
, 1970 An electron microscopic observation was made on the DNA's extracted from purified HeLa cell nuclei, mitochondria, and the whole cell, and fractionated by ethidium bromide-cesium chloride density gradient method or sucrose density gradient method. Nuclear
Hirata, Seiichi +4 more
core +1 more source