Results 101 to 110 of about 115,822 (353)
Advanced Science, EarlyView.Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan +11 more
wiley +1 more source
Effect of 360His mutation in apolipoprotein A-IV on plasma HDL-cholesterol response to dietary fat
Journal of Lipid Research, 1997 In order to determine whether genetic variability of apolipoprotein (apo) A-IV is responsible for the improvement in lipid profile when dietary saturated fats are replaced by carbohydrates or monounsaturated fats, 41 healthy male subjects were studied ...
S Jansen +11 more
doaj +1 more source
Changes in the nutrient content of American diets [PDF]
, 2011 As obesity and being overweight continue to increase in the United States, public concern is growing about the quality of American diets. We compare the changes in nutrients contributed by major food groups in the periods 1953-1980 and 1981-2008 and find
Huang, Kuo S., Huang, Sophia Wu
core +1 more source
Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology
Advanced Science, EarlyView.Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto +11 more
wiley +1 more source
A ketogenic diet reduces amyloid beta 40 and 42 in a mouse model of Alzheimer's disease
Nutrition & Metabolism, 2005 Background Alzheimer's disease (AD) is a progressive neurodegenerative disorder that primarily strikes the elderly. Studies in both humans and animal models have linked the consumption of cholesterol and saturated fats with amyloid-β (Aβ) deposition and ...
Van Leuven Fred +3 more
doaj +1 more source
Identification of genes affecting saturated fat acid content in Elaeis guineensis by genome-wide association analysis [PDF]
, 2018 Wei Xia +9 more
openalex +1 more source
A Natural Sweetener‐inducible Genetic Switch Controls Therapeutic Protein Expression in Mammals
Advanced Science, EarlyView.This study develops a natural sweetener, the psicose‐inducible transgene expression (PURE) system based on an Agrobacterium tumefaciens–derived transcriptional repressor PsiR. The PURE system is highly specific to psicose, being insensitive to other sugars and structurally similar molecules.
Longliang Qiao +16 more
wiley +1 more source
PLoS Medicine, 2012 BackgroundThe lack of association found in several cohort studies between dietary saturated fat and coronary heart disease (CHD) risk has renewed debate over the link between dietary fats and CHD.Methods and findingsWe assessed the relationship between ...
Kay-Tee Khaw +4 more
doaj +1 more source
(Tinjauan Pustaka) Efek Perbedaan Sumber Dan Struktur Kimia Asam Lemak Jenuh Terhadap Kesehatan [PDF]
, 2010 . For decades, all saturated fatty acids have always been judged as the only cause of cardiovascular disease without considering the difference of their sources and the length of their carbon chains.
Tuminah, S. (Sulistyowati)
core
3D Bioprinted Fat‐Myocardium Model Unravels the Role of Adipocyte Hypertrophy in Atrial Dysfunction
Advanced Science, EarlyView.A human‐derived 3D bioprinted fat–myocardium model is developed to investigate how adipocyte hypertrophy drives atrial dysfunction in obesity. Palmitate‐induced adipocyte hypertrophy promotes adipose dysfunction that impairs atrial cardiomyocyte metabolism and electrophysiology through both paracrine and direct interactions. This platform recapitulates
Lara Ece Celebi, Pinar Zorlutuna
wiley +1 more source