Results 101 to 110 of about 115,107 (353)

Effect of 360His mutation in apolipoprotein A-IV on plasma HDL-cholesterol response to dietary fat

Journal of Lipid Research, 1997
In order to determine whether genetic variability of apolipoprotein (apo) A-IV is responsible for the improvement in lipid profile when dietary saturated fats are replaced by carbohydrates or monounsaturated fats, 41 healthy male subjects were studied ...
S Jansen, J Lopez-Miranda, J M Ordovas, J L Zambrana, C Marin, M A Ostos, P Castro, R McPherson, F Lopez Segura, A Blanco, J A Jimenez Pereperez, F Perez-Jimenez   +11 more
doaj   +1 more source

Balanced Expression of the Diiron Oxygenase BioE Is Essential for Biotin Homeostasis in Elizabethkingia meningoseptica

Advanced Science, EarlyView.
BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang, Ying‐ying Fu, Xiaoqiang Yang, Qiuying Qin, Xinyu Su, Jiaming Fang, Yanhua Kang, Qingwen He, Zhi Ruan, Yongchang Xu   +9 more
wiley   +1 more source

Plasma phospholipid fatty acid concentration and incident coronary heart disease in men and women: the EPIC-Norfolk prospective study.

PLoS Medicine, 2012
BackgroundThe lack of association found in several cohort studies between dietary saturated fat and coronary heart disease (CHD) risk has renewed debate over the link between dietary fats and CHD.Methods and findingsWe assessed the relationship between ...
Kay-Tee Khaw, Marlin D Friesen, Elio Riboli, Robert Luben, Nicholas Wareham   +4 more
doaj   +1 more source

Quality characteristics of edible linseed oil [PDF]

, 2006
In this review the quality properties of linseed oil for food uses are discussed as well as factors affecting this quality. Linseed oil has a favourable fatty acid composition with a high linolenic acid content.
Gates, Fred, Kymäläinen, Hanna-Riitta, Nykter, Minna, Sjöberg, Anna-Maija   +3 more
core  

Plasma phospholipid fatty acid profiles confirm compliance to the dietary exchange of saturated with unsaturated fat in healthy men using full-fat or lower-fat dairy foods: results from the Reading, Imperial, Surrey, Saturated fat, Cholesterol Intervention (RISSCI) study [PDF]

, 2021
Laury Sellem, R. Antoni, A. Koutsos, E. Ozen, G. Wong, H. Ayyad, Barbara A. Fielding, M. Denise Robertson, Kim G. Jackson, Bruce A. Griffin, Julie A. Lovegrove   +10 more
openalex   +1 more source

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

Advanced Science, EarlyView.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu, Yajie Zhang, Yushi Tang, Hongli Hu, Ying Zhang, Junwen Xue, Hao Wang, Yecheng Wang, Chunfeng Liu, Jia Jia, Jian Cheng, Yongjun Cao   +11 more
wiley   +1 more source

A ketogenic diet reduces amyloid beta 40 and 42 in a mouse model of Alzheimer's disease

Nutrition & Metabolism, 2005
Background Alzheimer's disease (AD) is a progressive neurodegenerative disorder that primarily strikes the elderly. Studies in both humans and animal models have linked the consumption of cholesterol and saturated fats with amyloid-β (Aβ) deposition and ...
Van Leuven Fred, Wera Stefaan, Van der Auwera Ingrid, Henderson Samuel T   +3 more
doaj   +1 more source

Identification of genes affecting saturated fat acid content in Elaeis guineensis by genome-wide association analysis [PDF]

, 2018
Wei Xia, Tingting Luo, Wei Zhang, Annaliese S. Mason, Dongyi Huang, Xiaolong Huang, Wenqi Tang, Yajing Dou, Chunyu Zhang, Yong Xiao   +9 more
openalex   +1 more source

Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte‐Macrophage Crosstalk

Advanced Science, EarlyView.
Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan, Yuting Yong, Yuanshuai Li, Gaona Shi, Min Zhang, Lingfei Wan, Yue Zhao, Wenling Zhan, Yanli Lin, Qiaozhen Qin, Xupeng Chen, Yanli Ni, Haixu Chen, Wenzai Shi, Xiaomeng Guo, Juan Chen, Shuchen Liu, Youliang Wang, Bing Liu, Xinlong Yan   +19 more
wiley   +1 more source

Dipiperazine‐Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram‐Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes

Advanced Science, EarlyView.
By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong, Ting Guo, Yi Huang, Yangchun Ma, Weijin Chen, Jie Xue, Jun Jiang, Enhui Dong, Yue Kong, Hang Ding, Wenlong Zhang, Shutao Ma   +11 more
wiley   +1 more source