Results 21 to 30 of about 138,523 (261)
Saturated Fatty Acids and snoRNAs: Partners in Crime [PDF]
Cell Metabolism, 2011 Lipotoxicity describes the process of cellular dysfunction in response to lipid overload. In this issue of Cell Metabolism, Michel and colleagues (2011) provide evidence for a role of snoRNAs in palmitate-induced oxidative stress.
Mattijssen, F.B.J., Kersten, A.H.
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Metabolites, 2018 Macrophages are abundant within adipose tissue depots where they are exposed to fatty acids, leading to lipid accumulation. Herein, we have determined the effects of various fatty acids on the macrophage lipidome.
Kevin Huynh +5 more
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Saturated fatty acid intake and cardiovascular risk [PDF]
European Heart Journal, 2013 This editorial refers to ‘Dietary intake of saturated fatty acids and incident stroke and coronary heart disease in Japanese communities: the JPHC Study’, by K. Yamagishi et al. , doi:10.1093/eurheartj/eht043 Since the 1960s, clinical and animal studies have shown that reduction of dietary saturated fatty acid (SFA) consumption is associated with ...
Yasuhiko, Sakata, Hiroaki, Shimokawa
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
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Saturated Fats: Time to Assess Their Beneficial Role in a Healthful Diet
DieteticsSaturated fats are widely seen as undesirable components of a healthy diet, as a result of their illusory association with elevated serum cholesterol. The regulation of serum cholesterol is now better understood and a lack of polyunsaturated fatty acids,
Glen D. Lawrence
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Fatty Acid Composition of Goat and Sheep Milk: Transformation during Yogurt Production [PDF]
Техника и технология пищевых производств, 2019 Introduction. Information on the structure of fatty acids is crucial for production and promotion of goat and sheep milk in dairy industry. The profile of fatty acids of milk fat can affect the nutrition value and market value of dairy products.
Sadovoy V., Voblikova T., Permyakov A.
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The Chlorophosphonation of Saturated Fatty Acid
Journal of Japan Oil Chemists' Society, 1967 Lauric acid was chlorophosphonated under the following conditions : 0.15 mol of lauric acid was dissolved in 0.3 mol of phosphorus trichloride, followed by introduction of dried oxygen into the solution with the flow rate of 70 ml/min for 3 hr. The product was distilled under vucuum after treating with methanol.
Satoshi NAKASATO +2 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
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Fatty acid profile, volatiles and antibacterial screening of lipids of the sponge Fasciospongia cavernosa (Schmidt) collected from the Bay of Bengal (Orissa Coast) [PDF]
Journal of the Serbian Chemical Society, 2009 The fatty acid composition as well as the volatiles of a lipophilic extract from the marine sponge Fasciospongia cavernosa (Schmidt) was analysed. The fatty acids (FA) were characterized by linear saturated fatty acids (33.05 %), branched saturated fatty
PRAVAT MANJARI MISHRA +3 more
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