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Rapid Detection of Saxitoxin Using a Nucleic Acid Aptamer Biosensor Based on Graphene Oxide as a Fluorescence Quencher [PDF]

Toxins
Saxitoxin (STX) is a toxin with paralyzing and lethal properties, necessitating the development of a simple analytical method. This study developed a nucleic acid aptamer biosensor using graphene oxide (GO) as a fluorescence quencher for STX detection ...
Yi Jiao, Liqing Yang, Junping Hao, Yuhang Wen, Jianhua Wang, Hengchao E, Zhiyong Zhao, Yufeng Chen, Xianli Yang   +8 more
doaj   +2 more sources

Discovery of nuclear-encoded genes for the neurotoxin saxitoxin in dinoflagellates. [PDF]

PLoS ONE, 2011
Saxitoxin is a potent neurotoxin that occurs in aquatic environments worldwide. Ingestion of vector species can lead to paralytic shellfish poisoning, a severe human illness that may lead to paralysis and death.
Anke Stüken, Russell J S Orr, Ralf Kellmann, Shauna A Murray, Brett A Neilan, Kjetill S Jakobsen   +5 more
doaj   +1 more source

Origin of saxitoxin biosynthetic genes in cyanobacteria. [PDF]

PLoS ONE, 2009
BACKGROUND:Paralytic shellfish poisoning (PSP) is a potentially fatal syndrome associated with the consumption of shellfish that have accumulated saxitoxin (STX). STX is produced by microscopic marine dinoflagellate algae.
Ahmed Moustafa, Jeannette E Loram, Jeremiah D Hackett, Donald M Anderson, F Gerald Plumley, Debashish Bhattacharya   +5 more
doaj   +1 more source

Dataset of genome sequence, de novo assembly, and functional annotation of Ruegeria sp. (PBVC088), a marine bacterium associated with the toxin-producing harmful dinoflagellate, Pyrodinium bahamense var. compressum

Data in Brief, 2022
The dataset comprises a whole-genome sequence of Ruegeria sp. PBVC088, a symbiotic (Gram-negative) bacterium associated with Pyrodinium bahamense var.
Grace Joy Wei Lie Chin, Salley Venda Law, Kenneth Francis Rodrigues, Jaeyres Jani, Ann Anton   +4 more
doaj   +1 more source

Microfluidic Flow Injection Immunoassay System for Algal Toxins Determination: A Case of Study

Frontiers in Chemistry, 2021
A novel flow injection microfluidic immunoassay system for continuous monitoring of saxitoxin, a lethal biotoxin, in seawater samples is presented in this article.
Lorenzo Celio, Matteo Ottaviani, Rocco Cancelliere, Alessio Di Tinno, Alessio Di Tinno, Peter Panjan, Peter Panjan, Adama Marie Sesay, Adama Marie Sesay, Laura Micheli   +9 more
doaj   +1 more source

Biosynthesis of Saxitoxin in Marine Dinoflagellates: An Omics Perspective

Marine Drugs, 2020
Saxitoxin is an alkaloid neurotoxin originally isolated from the clam Saxidomus giganteus in 1957. This group of neurotoxins is produced by several species of freshwater cyanobacteria and marine dinoflagellates.
Muhamad Afiq Akbar, Nurul Yuziana Mohd Yusof, Noor Idayu Tahir, Asmat Ahmad, Gires Usup, Fathul Karim Sahrani, Hamidun Bunawan   +6 more
doaj   +1 more source

Insights into Alexandrium minutum Nutrient Acquisition, Metabolism and Saxitoxin Biosynthesis through Comprehensive Transcriptome Survey

Biology, 2021
The toxin-producing dinoflagellate Alexandrium minutum is responsible for the outbreaks of harmful algae bloom (HABs). It is a widely distributed species and is responsible for producing paralytic shellfish poisoning toxins.
Muhamad Afiq Akbar, Nurul Yuziana Mohd Yusof, Fathul Karim Sahrani, Gires Usup, Asmat Ahmad, Syarul Nataqain Baharum, Nor Azlan Nor Muhammad, Hamidun Bunawan   +7 more
doaj   +1 more source

Physiological Effects of Oxidative Stress Caused by Saxitoxin in the Nematode Caenorhabditis elegans

Marine Drugs, 2023
Saxitoxin (STX) causes high toxicity by blocking voltage-gated sodium channels, and it poses a major threat to marine ecosystems and human health worldwide.
Haiyan Wu, Balakrishnan Prithiviraj, Zhijun Tan   +2 more
doaj   +1 more source

Evolution and Distribution of Saxitoxin Biosynthesis in Dinoflagellates

Marine Drugs, 2013
Numerous species of marine dinoflagellates synthesize the potent environmental neurotoxic alkaloid, saxitoxin, the agent of the human illness, paralytic shellfish poisoning.
Kjetill S. Jakobsen, Shauna A. Murray, Russell J. S. Orr, Anke Stüken   +3 more
doaj   +1 more source

Accumulation and elimination dynamics of the hydroxybenzoate saxitoxin analogues in mussels Mytilus galloprovincialis exposed to the toxic marine Dinoflagellate Gymnodinium catenatum [PDF]

, 2018
Paralytic shellfish poisoning (PSP) is a severe food-borne illness, caused by the ingestion of seafood containing paralytic shellfish toxins (PST), which are naturally produced by marine dinoflagellates and accumulate in shellfish during algae blooms ...
Braga, Ana, Reis Costa, Pedro, Turner, Andrew   +2 more
core   +1 more source