Docking Simulation of the Binding Interactions of Saxitoxin Analogs Produced by the Marine Dinoflagellate Gymnodinium catenatum to the Voltage-Gated Sodium Channel Nav1.4 [PDF]
, 2016 Saxitoxin (STX) and its analogs are paralytic alkaloid neurotoxins that block the voltage-gated sodium channel pore (Nav), impeding passage of Na+ ions into the intracellular space, and thereby preventing the action potential in the peripheral nervous ...
Band-Schmidt, Christine J. +4 more
core +5 more sources
Surface Plasmon Spectroscopic Detection of Saxitoxin
Sensors, 2007 For the surface-optoelectronic study of Saxitoxin sensing, we fabricated self-assembled calix[4]arene derivative monolayers as the recognition-functional interfaces ona gold surface.
Kwangnak Koh +7 more
doaj +1 more source
Paralytic shellfish toxins and ocean warming: bioaccumulation and ecotoxicological responses in jujvenile Gilthead Seabream (Sparus aurata) [PDF]
, 2019 Warmer seawater temperatures are expected to increase harmful algal blooms (HABs) occurrence, intensity, and distribution. Yet, the potential interactions between abiotic stressors and HABs are still poorly understood from ecological and seafood safety ...
Anacleto, Patrícia +6 more
core +1 more source
PLoS ONE, 2011 Saxitoxin and its analogs cause the paralytic shellfish-poisoning syndrome, adversely affecting human health and coastal shellfish industries worldwide.
Troco K Mihali +2 more
doaj +1 more source
Saxitoxin Level Comparation in Bali Sardine (Sardinella Lemuru) in Bali Strait in Different Monsoons
Research Journal of Life Science, 2017 Sardinella fish (Sardinella lemuru) is a species of important pelagic fish from the family of Clupeidae found in Bali Strait. The dynamic condition of Bali Strait makes it fertile which is identical with plankton blooming.
Endang Yuli Herawati +3 more
doaj +1 more source
Diversity and biosynthetic potential of culturable microbes associated with toxic marine animals [PDF]
, 2013 Tetrodotoxin (TTX) is a neurotoxin that has been reported from taxonomically diverse organisms across 14 different phyla. The biogenic origin of tetrodotoxin is still disputed, however, TTX biosynthesis by host-associated bacteria has been reported.
Chau, Rocky +3 more
core +4 more sources
Visible Fluorescence Chemosensor for Saxitoxin [PDF]
The Journal of Organic Chemistry, 2007 Absorption spectra of a number of shellfish extracts have been obtained and reveal prominent absorptions in all samples at 210 and 260 nm and at 325 nm in some of them. These absorptions preclude the use of chromophores with similar absorptions in testing of shellfish samples for paralytic shellfish toxins.
Robert E, Gawley +4 more
openaire +2 more sources
Improved Accuracy of Saxitoxin Measurement Using an Optimized Enzyme-Linked Immunosorbent Assay
Toxins, 2019 Paralytic shellfish poisoning (PSP) is precipitated by a family of toxins produced by harmful algae, which are consumed by filter-feeding and commercially popular shellfish.
Jennifer R. McCall +4 more
doaj +1 more source
Investigating diet as the source of tetrodotoxin in Pleurobranchaea maculata [PDF]
, 2014 The origin of tetrodotoxin (TTX) is highly debated; researchers have postulated either an endogenous or exogenous source with the host accumulating TTX symbiotically or via food chain transmission.
Adamson, Janet E. +6 more
core +2 more sources
Evolutionary acquisition and loss of saxitoxin biosynthesis in dinoflagellates: The second "core" gene, sxtG [PDF]
, 2013 Saxitoxin and its derivatives are potent neurotoxins produced by several cyanobacteria and dinoflagellate species. SxtA is the initial enzyme in the biosynthesis of saxitoxin.
Jakobsen, KS +3 more
core +1 more source