Results 131 to 140 of about 925 (177)

Derivatives of saxitoxin

Bioorganic Chemistry, 1981
Abstract The preparation, spectral characterization, chromatographic and biological properties of several derivatives of saxitoxin, a highly potent neurotoxin, are described. Derivatives include decarbamoylsaxitoxin, both epimers of dihydrosaxitoxin (α- and β-saxitoxinol) and both epimers of decarbamoylsaxitoxinol, as well as several isotopically ...
Frank E. Koehn, Vartan E. Ghazarossian, E.J. Schantz, H.K. Schnoes, F.M. Strong   +4 more
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First report of saxitoxin in octopi

Toxicon, 2004
We report for the first time, the presence of saxitoxin (STX) in a common cephalopod, Octopus (Abdopus) sp. 5, collected from Cooke Point on the northern coastline of Western Australia. Sodium channel and saxiphilin based radio-receptor assays detected saxitoxin-like binding in octopi extracts.
Robertson, Alison, Stirling, David, Robillot, Cedric, Llewellyn, Lyndon, Negri, Andrew   +4 more
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Differentiation of the actions of tetrodotoxin and saxitoxin

Toxicon, 1967
Abstract While tetrodotoxin and saxitoxin are very similar in their actions, they can be differentiated biologically by the observation that newts of the genus Taricha are resistant to tetrodotoxin but not to saxitoxin. The resistance of these newts is due to a remarkable insensitivity of the somatic motor nerves to tetrodotoxin.
C Y, Kao, F A, Fuhrman
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Occurrence of saxitoxin in puffer fish

Toxicon, 1984
Three species of puffer fish, Takifugu poecilonotus, T. vermicularis and T. radiatus, were examined for the presence of toxic components other than tetrodotoxin. Saxitoxin, a paralytic shellfish toxin, was found in the livers, ovaries and digestive tracts of the first two species but not in the last species.
M, Nakamura, Y, Oshima, T, Yasumoto
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Chemosensors for the Marine Toxin Saxitoxin

Journal of the American Chemical Society, 2002
Eleven anthracylmethyl crown ethers have been synthesized and evaluated as fluorescence sensors for the marine toxin saxitoxin. Fluorescence enhancement data are consistent with a 1:1 binding complex for all crowns. The binding constants are in the range of 10(4) M(-)(1) in ammonium phosphate buffer (pH 7.1) in 80% ethanol solvent.
Robert E, Gawley, Sandra, Pinet, Claudia M, Cardona, Probal K, Datta, Tong, Ren, Wayne C, Guida, Jason, Nydick, Roger M, Leblanc   +7 more
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ChemInform Abstract: STRUCTURE OF A CRYSTALLINE DERIVATIVE OF SAXITOXIN. STRUCTURE OF SAXITOXIN

Chemischer Informationsdienst, 1976
AbstractAufgrund der 13C‐NMR‐Spektroskopie liegt Saxitoxin, das Gift von Schalentieren, in wäß‐ rigen Lösungen als Hydrat vor.
JON BORDNER, WILLIAM E. THIESSEN, HANS A. BATES, HENRY RAPOPORT   +3 more
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Total Synthesis of (−)‐ and (+)‐Decarbamoyloxysaxitoxin and (+)‐Saxitoxin

Chemistry – An Asian Journal, 2009
AbstractPlaying the sax: The enantioselective total syntheses of (−)‐ and (+)‐decarbamoyloxysaxitoxin (doSTX) and (+)‐saxitoxin (STX) are reported. A new methodology was developed for the synthesis of STXs, featuring discriminative reduction of the nitro group and NO bond in nitroisoxazolidine.magnified imageEnantioselective total syntheses of ...
Osamu, Iwamoto, Ryoko, Shinohara, Kazuo, Nagasawa   +2 more
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Saxitoxin

2000
Abstract Saxitoxin (STX), a heat-stable neurotoxin produced by some marine dinoflagellates, binds specifically to voltagesensitive sodium channels. The organisms that produce this molecule are thought to be responsible for the so-called red tides observed since antiquity. The first record of such an event appeared in Exodus 7:20-21:
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Study of the binding way between saxitoxin and its aptamer and a fluorescent aptasensor for detection of saxitoxin

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2018
Aptamers could be used to construct simple and effective biosensor because the conformational switch of aptamer upon target binding is easy to be transferred to optical or electrochemical signals. Nevertheless, we found that the binding between saxitoxin (STX) and aptamer (M-30f) is not accompanied with conformational switch.
Sheng Cheng, Bin Zheng, Dongbao Yao, Shenglong Kuai, Jingjing Tian, Haojun Liang, Yunsheng Ding   +6 more
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Structure of a crystalline derivative of saxitoxin. Structure of saxitoxin

Journal of the American Chemical Society, 1975
J, Bordner, W E, Thiessen, H A, Bates, H, Rapoport   +3 more
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