A novel and safe SmartCap® SC101 to develop the COVID-19 mRNA vaccine STP2104 inducing potent immune responses in humans [PDF]
We have developed a 5′-capping library screening (CLS) method using over 30 different novel cap analogues. The optimal 5′-cap for the coronavirus disease 2019 (COVID-19) mRNA vaccine STP2104 was selected and applied.
Rachel Kim +23 more
doaj +5 more sources
Discovery and development of a safe and efficient COVID-19 mRNA vaccine, STP2104, using a novel capping library screening method [PDF]
Messenger RNA (mRNA) vaccines represent a critical avenue for coronavirus disease 2019 (COVID-19) prevention. We developed a COVID-19 mRNA vaccine encoding a codon-optimized full-length ancestral spike (S) protein with a signal peptide, which employs our
Kanghyun Choi +36 more
doaj +2 more sources
Nitrogen Fertilizer Recommendations for Sugarcane Production for Sugar on Florida Sand Soils
Sands used in sugarcane production in Florida have low levels of organic matter, silt, and clay, and they provide little nitrogen (N) through mineralization of organic matter and possess a low capacity for N retention as a result.
J. Mabry McCray +2 more
doaj +5 more sources
Background The unicellular cyanobacterium Synechocystis sp. PCC 6803 has been widely used as a photoautotrophic host for synthetic biology studies. However, as a green chassis to capture CO2 for biotechnological applications, the genetic toolbox for ...
Deng Liu, Himadri B. Pakrasi
doaj +1 more source
Expression of tardigrade disordered proteins impacts the tolerance to biofuels in a model cyanobacterium Synechocystis sp. PCC 6803. [PDF]
Zhang H +5 more
europepmc +1 more source
Monitoring lineages of growing and dividing bacteria reveals an inducible memory of mar operon expression. [PDF]
Guet CC +4 more
europepmc +1 more source
Artificial intelligence and change management in small and medium-sized enterprises: an analysis of dynamics within adaptation initiatives. [PDF]
Lemos SIC +4 more
europepmc +1 more source
Developing a Fluorescent Inducible System for Free Fucose Quantification in Escherichia coli. [PDF]
Nuñez S, Barra M, Garrido D.
europepmc +1 more source
Screening and Identification of Trichoderma Strains isolated from Natural Habitats in China with Potential Agricultural Applications. [PDF]
Xue M +9 more
europepmc +1 more source
Microbial production of the plant flavanone hesperetin from caffeic acid. [PDF]
Hanko EKR +10 more
europepmc +1 more source

