Results 11 to 20 of about 312 (58)

Exploring native genetic elements as plug-in tools for synthetic biology in the cyanobacterium Synechocystis sp. PCC 6803

open access: yesMicrobial Cell Factories, 2018
Background The unicellular cyanobacterium Synechocystis sp. PCC 6803 has been widely used as a photoautotrophic host for synthetic biology studies. However, as a green chassis to capture CO2 for biotechnological applications, the genetic toolbox for ...
Deng Liu, Himadri B. Pakrasi
doaj   +1 more source

Downregulation of an Evolutionary Young miR‐1290 in an iPSC‐Derived Neural Stem Cell Model of Autism Spectrum Disorder

open access: yesStem Cells International, Volume 2019, Issue 1, 2019., 2019
The identification of several evolutionary young miRNAs, which arose in primates, raised several possibilities for the role of such miRNAs in human‐specific disease processes. We previously have identified an evolutionary young miRNA, miR‐1290, to be essential in neural stem cell proliferation and neuronal differentiation.
Dalia Moore   +11 more
wiley   +1 more source

Measuring Colloidal Forces With Atomic Force Microscopy 1: Salt Influence on Hydrophobic and Hydrophilic Interactions

open access: yesMicroscopy Research and Technique, Volume 88, Issue 6, Page 1626-1634, June 2025.
Colloidal forces play an important role in many life phenomena. Here, we present the preparation of hydrophobic and hydrophilic systems for the study of colloidal forces by AFM. The data are modeled using an extended DLVO model. ABSTRACT Colloidal forces are essential for maintaining the stability and functionality of colloidal systems, affecting ...
Luis N. Ponce‐Gonzalez   +2 more
wiley   +1 more source

Rational Design of Lipid Nanoparticles for Enhanced mRNA Vaccine Delivery via Machine Learning

open access: yesSmall, Volume 21, Issue 8, February 25, 2025.
This study applies machine learning (ML) to identify ionizable lipids for enhanced mRNA delivery. A random forest regression model is used to analyze lipid nanoparticles (LNPs) and predict mRNA expression efficiency based on features regarding chemical substructure and LNP composition.
Seo‐Hyeon Bae   +27 more
wiley   +1 more source

Microbial production of the plant flavanone hesperetin from caffeic acid. [PDF]

open access: yesBMC Res Notes, 2023
Hanko EKR   +10 more
europepmc   +1 more source

Biosynthesis of natural and halogenated plant monoterpene indole alkaloids in yeast. [PDF]

open access: yesNat Chem Biol, 2023
Bradley SA   +31 more
europepmc   +1 more source

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