Results 91 to 100 of about 954,074 (407)

Origin of electrochemical activity in nano-Li2MnO3; Stabilization via a 'point defect scaffold' [PDF]

, 2015
Molecular dynamics (MD) simulations of the charging of Li2MnO3 reveal that the reason nanocrystalline-Li2MnO3 is electrochemically active, in contrast to the parent bulk-Li2MnO3, is because in the nanomaterial the tunnels, in which the Li ions reside ...
Barnard, Boulineau, Bruce, Cho, Croy, Dean C. Sayle, DeSouza, Duvel, Francesco Caddeo, Gale, Goniakowski, Jain, Kenneth M. Kgatwane, Lee, Lei, Lim, Malavasi, Nkwe O. Monama, Pergolesi, Phuti E. Ngoepe, Sayle, Sayle, Sayle, Sayle, Sayle, Smith, Strobel, Thackeray, Thackeray, Thi X. T. Sayle, Tompsett, Wang, Zhang   +32 more
core   +1 more source

Advances in Porous Scaffold Design for Bone and Cartilage Tissue Engineering and Regeneration.

Tissue engineering. Part B, Reviews, 2019
IMPACT STATEMENT Challenges in musculoskeletal tissue regeneration affect millions of patients globally. Scaffolds for tissue engineering bone and cartilage provide promising solutions that increase healing and decrease need for complicated surgical ...
A. Cheng, Z. Schwartz, A. Kahn, Xiyu Li, Zhenxing Shao, Muyang Sun, Y. Ao, B. Boyan, Haifeng Chen   +8 more
semanticscholar   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma, Jennifer R. Deuis, Xinying Jia, Theo Crawford, Sassan Rahnama, Eivind A. B. Undheim, Irina Vetter, Yanni K. ‐Y. Chin, Mehdi Mobli   +8 more
wiley   +1 more source

Immunological Compatibility Status of Placenta-Derived Stem Cells is Mediated by Scaffold 3D Structure [PDF]

, 2018
Placenta-derived amniotic epithelial cells (AECs), a great cell source for tissue engineering and stem cell therapy, are immunologically inert in their native state; however, immunological changes in these cells after culture and differentiation have ...
Azizian, Sara, Bahrami, Soheyl, Katami, Fatemeh, Modaresifar, Khashayar, Mosaffa, Nariman, Niknejad, Hassan, Peirovi, Habibollah, Redl, Heinz, Tayebi, Lobat   +8 more
core   +2 more sources

Nghiên cứu chế tạo scaffold polylactic acid bằng phương pháp tách pha dung môi

Tạp chí Khoa học Đại học Cần Thơ, 2019
Scaffold - dạng cấu trúc khung xốp, là một thành phần quan trọng trong kỹ thuật mô vì nó góp phần vào việc tạo nên cấu trúc mô ba chiều. Vì thế, đề tài này được tiến hành nhằm nghiên cứu chế tạo scaffold từ polymer phân hủy sinh học polylactic acid (PLA).
Hồ Quốc Phong, Tào Thế Dương, Trần Sỹ Nam, Huỳnh Liên Hương   +3 more
doaj   +1 more source

Stöttningsinteraktion: Undervisningssituationens scaffolding?

Kapet, 2023
I den här artikeln prövas ett nytt svenskt begrepp för engelskans scaffolding, nämligen stöttningsinteraktion. Syftet är att med hjälp av en adekvat svensk benämning skapa en gemensam förståelse av ett komplext begrepp och därigenom vidga förståelsen för dess användning i undervisningssammanhang.
Forsling, Karin, Tjernberg, Catharina
openaire   +2 more sources

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

Simultaneous elastic shape optimization for a domain splitting in bone tissue engineering

, 2018
This paper deals with the simulateneous optimization of a subset $\mathcal{O}_0$ of some domain $\Omega$ and its complement $\mathcal{O}_1 = \Omega \setminus \overline{\mathcal{O}}_0$ both considered as separate elastic objects subject to a set of ...
Dondl, Patrick, Poh, Patrina S. P., Rumpf, Martin, Simon, Stefan   +3 more
core   +1 more source

The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat. [PDF]

, 2013
Human positive transcription elongation factor b (P-TEFb) phosphorylates RNA polymerase II and regulatory proteins to trigger elongation of many gene transcripts.
Alber, Tom, Bao, Katherine, Birnberg, Andrew, Chou, Seemay, Krogan, Nevan J, Schulze-Gahmen, Ursula, Upton, Heather, Zhou, Qiang   +7 more
core   +1 more source

Scaffold-constrained molecular generation [PDF]

, 2020
One of the major applications of generative models for drug Discovery targets the lead-optimization phase. During the optimization of a lead series, it is common to have scaffold constraints imposed on the structure of the molecules designed. Without enforcing such constraints, the probability of generating molecules with the required scaffold is ...
arxiv   +1 more source