Results 31 to 40 of about 512,987 (302)
, 2022 The construction of a virtual library (VL) consisting of novel molecules based on structure–activity relationships is crucial for lead optimization in rational drug design.
Kazuma Kaitoh +3 more
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Innovative Human Three-Dimensional Tissue-Engineered Models as an Alternative to Animal Testing
Bioengineering, 2020 Animal testing has long been used in science to study complex biological phenomena that cannot be investigated using two-dimensional cell cultures in plastic dishes.
Patrick Bédard +6 more
doaj +1 more source
Aligned Collagen Sponges with Tunable Pore Size for Skeletal Muscle Tissue Regeneration
Journal of Functional Biomaterials, 2023 Volumetric muscle loss (VML) is a traumatic injury where at least 20% of the mass of a skeletal muscle has been destroyed and functionality is lost. The standard treatment for VML, autologous tissue transfer, is limited as approximately 1 in 10 grafts ...
Natalie G. Kozan +3 more
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Advanced Biosystems, 2017 Scaffolds are instrumental in the engineering of functional tissues, and therefore have been an intense area of interest within regenerative biology and medicine in areas of research and development. Many approaches exist for creating scaffolds with either natural or synthetic advanced materials, which are subsequently coupled with cells and other ...
openaire +3 more sources
Applied Sciences, 2020 Synthetic scaffolding for bone tissue engineering (BTE) has been widely utilized. The scaffold for BTE requires sufficient porosity as a template for bone cell development and growth so that it can be used in the treatment of bone defects and fractures ...
Aminatun +6 more
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Functionally gradient tissue scaffold design and deposition path planning for bio-additive processes [PDF]
, 2013 A layer-based tissue scaffold is designed with heterogeneous internal architecture. The proposed layer-based design uses a bi-layer pattern of radial and spiral layer consecutively to generate functionally gradient porosity following the geometry of the ...
Khoda, AKM Bashirul +2 more
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, 2002 A study investigated the use of software scaffolding for student design and construction of multimedia environments as a cross-curricular learning activity. The students (11 to 13 years) in a Melbourne, Australia, girls’ school, worked in a technologically enriched learning environment and were experienced multimedia developers. The girls were provided
Anne McDougall, Martin Boyle
openaire +2 more sources
Interventional Cardiology Review, 2014 Percutaneous coronary intervention (PCI) has undergone major advances including the evolution in stent technology, from bare metal stents (BMS), to their drug eluting counterparts, to the development of bioresorbable scaffolds (BRS). The primary notion of BRS was to facilitate complete vascular healing and restore normal endothelial function following ...
Sidakpal, Panaich +2 more
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HeliyonBackground: Most construction mishaps were caused by scaffolding incidents despite implementing various safety measures, and the association with human factors like fatigue has been widely reported.
Hanizah Mohd Yusoff +5 more
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BioengineeringCell culture in two dimensions has been the main instrument in cellular and molecular biology. But there are limitations to two-dimensional culture when it comes to tissue engineering and in vivo reproduction.
Mohammad Zafaryab, Komal Vig
doaj +1 more source