Results 41 to 50 of about 1,015,982 (386)

Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive Compounds

open access: yesMolecules, 2018
Many naturally occurring substances, traditionally used in popular medicines around the world, contain the coumarin moiety. Coumarin represents a privileged scaffold for medicinal chemists, because of its peculiar physicochemical features, and the ...
A. Stefanachi   +4 more
semanticscholar   +1 more source

Bioresorbable Scaffolds [PDF]

open access: yesInterventional Cardiology Review, 2014
Percutaneous coronary intervention (PCI) has undergone major advances including the evolution in stent technology, from bare metal stents (BMS), to their drug eluting counterparts, to the development of bioresorbable scaffolds (BRS). The primary notion of BRS was to facilitate complete vascular healing and restore normal endothelial function following ...
Sidakpal, Panaich   +2 more
openaire   +2 more sources

Development of a Computational Model for Cell Activity in a Nano-Scaffold [PDF]

open access: yes, 2020
Tissue engineering utilizes nano-scaffolds to direct cell growth and control cell behavior. Since cells occupy specific spaces within extracellular matrix (ECM) it’s important to understand how the geometry of these spaces influence cell behaviors such ...
Babcock, Ethan, Luke, Bethany
core   +1 more source

Remotely triggered scaffolds for controlled release of pharmaceuticals [PDF]

open access: yes, 2013
Fe3O4-Au hybrid nanoparticles (HNPs) have shown increasing potential for biomedical applications such as image guided stimuli responsive drug delivery.
Hoskins, Clare   +3 more
core   +2 more sources

Biomaterial-Based Activation and Expansion of Tumor-Specific T Cells

open access: yesFrontiers in Immunology, 2019
Traditional tumor vaccination approaches mostly focus on activating dendritic cells (DCs) by providing them with a source of tumor antigens and/or adjuvants, which in turn activate tumor-reactive T cells.
Marjolein Schluck   +11 more
doaj   +1 more source

Scaffolder - Software for Reproducible Genome Scaffolding.

open access: yesNature Precedings, 2011
Abstract Background: Assembly of short-read sequencing data can result in a fragmented non-contiguous series of genomic sequences. Therefore a common step in a genome project is to join neighboring sequence regions together and fill gaps in the assembly using additional sequences.
Michael D. Barton, Hazel A. Barton
openaire   +2 more sources

Bioactive composites for bone tissue engineering [PDF]

open access: yes, 2010
One of the major challenges of bone tissue engineering is the production of a suitable scaffold material. In this review the current composite materials options available are considered covering both the methods of both production and assessing the ...
Tanner, K.E.
core   +1 more source

The Mottled Capsid of the Salmonella Giant Phage SPN3US, a Likely Maturation Intermediate with a Novel Internal Shell

open access: yesViruses, 2020
“Giant” phages have genomes of >200 kbp, confined in correspondingly large capsids whose assembly and maturation are still poorly understood. Nevertheless, the first assembly product is likely to be, as in other tailed phages, a procapsid that ...
J. Bernard Heymann   +9 more
doaj   +1 more source

Composite Biomaterials Based on Sol-Gel Mesoporous Silicate Glasses: A Review

open access: yesBioengineering, 2017
Bioactive glasses are able to bond to bone and stimulate the growth of new tissue while dissolving over time, which makes them ideal materials for regenerative medicine. The advent of mesoporous glasses, which are typically synthesized via sol-gel routes,
Francesco Baino   +2 more
doaj   +1 more source

Application of Collagen Scaffold in Tissue Engineering: Recent Advances and New Perspectives

open access: yesPolymers, 2016
Collagen is the main structural protein of most hard and soft tissues in animals and the human body, which plays an important role in maintaining the biological and structural integrity of the extracellular matrix (ECM) and provides physical support to ...
Chanjuan Dong, Y. Lv
semanticscholar   +1 more source

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