Results 61 to 70 of about 349,978 (268)

Influence of Structure–Property Relationships of Polymeric Biomaterials for Engineering Multicellular Spheroids

Bioengineering
Two-dimensional cell culture systems lack the ability to replicate the complex, three-dimensional (3D) architecture and cellular microenvironments found in vivo.
Sheetal Chowdhury, Amol V. Janorkar
doaj   +1 more source

Biocompatibility Issue Of Tissue Engineered Heart Valves

Archives of Metallurgy and Materials, 2015
Tissue engineering is a new field of knowledge which creates the possibilities for producing bioactive cardiac prostheses that will characterize by biomechanical and morphological properties similar to native tissue.
Wilczek P.
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Functional scaffolding and self-scaffolding [PDF]

New Ideas in Psychology, 2005
Abstract Models of the nature of representation and cognition ground and constrain models of the construction of representation in learning and development: models of what is being constructed ground and constrain models of the processes of construction.
openaire   +1 more source

Response to Article “Oriented Graphene Oxide Scaffold Promotes Nerve Regeneration in vitro and in vivo” [Letter]

International Journal of Nanomedicine
Novrynda Eko Satriawan,1,* Ariyani Noviantari1,2,* 1Doctoral Program in Biomedical Science, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; 2Center for Biomedical Research, Research Organization for Health, National Research and ...
Satriawan NE, Noviantari A
doaj  

Biliary Injuries Repair Using Copolymeric Scaffold: A Systematic Review and In Vivo Experimental Study

Journal of Functional Biomaterials
Background: Common bile duct (CBD) treatments are often associated with complications, limiting long-term efficacy. To overcome these issues, polymeric grafts have been suggested as promising alternatives, since they are highly customizable ...
Salvatore Buscemi, Giulia Bonventre, Andrea Gottardo, Mariano Licciardi, Fabio Salvatore Palumbo, Giovanni Cassata, Luca Cicero, Giulia Lo Monte, Roberto Puleio, Attilio Ignazio Lo Monte   +9 more
doaj   +1 more source

3D Cardiac Cell Culture: A Critical Review of Current Technologies and Applications

Frontiers in Cardiovascular Medicine, 2019
Three-dimensional (3D) cell culture is often mentioned in the context of regenerative medicine, for example, for the replacement of ischemic myocardium with tissue-engineered muscle constructs.
Christian Zuppinger
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Bionic Nanostructures Create Mechanical Signals to Mediate the Composite Structural Bone Regeneration Through Multi‐System Regulation

Advanced Science
Regenerating bone defects has long been recognized as a significant clinical challenge. Drawing inspiration from the structure and properties of natural bone, bionic nanomaterials have emerged as a focal point in the field of bone tissue engineering ...
Yangfan Pei, Yihan Wang, Jingxia Chen, Jing Zhou, Yuzhu Han, Xiuyu Liu, Siyu Chen, Sheng Chen, Dixin He, Yunxiao Wu, Huixin Lv, Yanmin Zhou   +11 more
doaj   +1 more source