Results 51 to 60 of about 723,869 (275)

Micro computed tomography based finite element models of calcium phosphate scaffolds for bone tissue engineering [PDF]

, 2016
Bone is a living tissue that is able to regenerate by itself. However, when severe bone defects occur, the natural regeneration may be impaired. In these cases, bone graft substitutes can be used to induce the natural healing process.
Jung, Timo Karl
core  

Remotely triggered scaffolds for controlled release of pharmaceuticals [PDF]

, 2013
Fe3O4-Au hybrid nanoparticles (HNPs) have shown increasing potential for biomedical applications such as image guided stimuli responsive drug delivery.
Hoskins, Clare, Lees, Martin R., McGarvey, David J., Roach, Paul, Ph.D.   +3 more
core   +2 more sources

Design and development of a fibrous structure for the potential treatment of spinal cord injury using parametric modelling in Rhinoceros 3D®

AUTEX Research Journal
Spinal cord injury (SCI) consists of partial or complete damage to the organ’s functions. Injuries can be traumatic or non-traumatic. New investigations have pointed out different paths in terms of spinal cord regeneration.
de Aguiar Souza Ivis, Kohan Lais, Rocha Joana M., da Silva Filho Maurício José, Peixoto Joaquim Jorge, Fangueiro Raul, Ferreira Diana S. P.   +6 more
doaj   +1 more source

Application of Scaffold-Based Drug Delivery in Oral Cancer Treatment: A Novel Approach

Pharmaceutics
This comprehensive review consolidates insights from two sources to emphasize the transformative impact of scaffold-based drug delivery systems in revolutionizing oral cancer therapy.
Elham Saberian, Andrej Jenča, Adriána Petrášová, Hadi Zare-Zardini, Meysam Ebrahimifar   +4 more
doaj   +1 more source

Promoting external inosculation of prevascularised tissue constructs by pre-cultivation in an angiogenic extracellular matrix [PDF]

European Cells & Materials, 2010
The engineering of preformed microvessels offers the promising opportunity to rapidly vascularise implanted tissue constructs by the process of inosculation.
D Eglin, M Alini, MD Menger, H Mussawy, S Schuler, MW Laschke   +5 more
doaj  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Bioactive composites for bone tissue engineering [PDF]

, 2010
One of the major challenges of bone tissue engineering is the production of a suitable scaffold material. In this review the current composite materials options available are considered covering both the methods of both production and assessing the ...
Tanner, K.E.
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Cell-scaffold interactions in the bone tissue engineering triad [PDF]

European Cells & Materials, 2013
Bone tissue engineering has emerged as one of the leading fields in tissue engineering and regenerative medicine. The success of bone tissue engineering relies on understanding the interplay between progenitor cells, regulatory signals, and the ...
CM Murphy, FJ O’Brien, DG Little, A Schindeler   +3 more
doaj  

Research progress on injectable hydrogel scaffolds in dental pulp regeneration

口腔疾病防治, 2022
Tissue engineering provides a new possibility for pulp regeneration. As one of the three elements of tissue engineering, scaffolds have attracted increasing attention.
FANG Na, LI Xiangwei
doaj   +1 more source