Results 61 to 70 of about 1,015,982 (386)

Evolutionary and molecular foundations of multiple contemporary functions of the nitroreductase superfamily. [PDF]

, 2017
Insight regarding how diverse enzymatic functions and reactions have evolved from ancestral scaffolds is fundamental to understanding chemical and evolutionary biology, and for the exploitation of enzymes for biotechnology.
Akiva, Eyal, Babbitt, Patricia C, Copp, Janine N, Tokuriki, Nobuhiko   +3 more
core   +1 more source

Numerical Accuracy Comparison of Two Boundary Conditions Commonly used to Approximate Shear Stress Distributions in Tissue Engineering Scaffolds Cultured under Flow Perfusion

, 2018
Flow-induced shear stresses have been found to be a stimulatory factor in pre-osteoblastic cells seeded in 3D porous scaffolds and cultured under continuous flow perfusion.
Alam, Ali, Alvarez-Barreto, Bacabac, Bakker, Bergemann, Bhatnagar, Black, Brindley, Campos Marin, Chen, Cioffi, Cioffi, Delloye, Efendiev, Graham, Guyot, Guyot, Habashi, Hendrikson, Hossain, Jungreuthmayer, Kim, Kim, Lakhotia, Liu, Maes, Maes, Miyashita, Olivares, Ozgumus, Papavassiliou, Pham, Pham, Porter, Qian, Raimondi, Shakhawath Hossain, Sikavitsas, Simmons, Stolberg, Sukop, Towns, Van Bael, VanGordon, Verbruggen, Voronov, Voronov, Voronov, Voronov, Wang, Williams, Wu, Wyllie, Yourek, Zermatten, Zhao   +56 more
core   +1 more source

Enlightenment of Growth Plate Regeneration Based on Cartilage Repair Theory: A Review

Frontiers in Bioengineering and Biotechnology, 2021
The growth plate (GP) is a cartilaginous region situated between the epiphysis and metaphysis at the end of the immature long bone, which is susceptible to mechanical damage because of its vulnerable structure.
Xianggang Wang, Xianggang Wang, Zuhao Li, Zuhao Li, Chenyu Wang, Haotian Bai, Haotian Bai, Zhonghan Wang, Zhonghan Wang, Yuzhe Liu, Yuzhe Liu, Yirui Bao, Ming Ren, Ming Ren, He Liu, He Liu, Jincheng Wang, Jincheng Wang   +17 more
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Designing heterogeneous porous tissue scaffolds for additive manufacturing processes [PDF]

, 2013
A novel tissue scaffold design technique has been proposed with controllable heterogeneous architecture design suitable for additive manufacturing processes.
Khoda, AKM Bashirul, Koc, Bahattin, Koç, Bahattin, Ozbolat, Ibrahim T., Özbolat, İbrahim T.   +4 more
core   +1 more source

A sex difference in the response of the rodent postsynaptic density to synGAP haploinsufficiency [PDF]

, 2020
SynGAP is a postsynaptic density (PSD) protein that binds to PDZ domains of the scaffold protein PSD-95. We previously reported that heterozygous deletion of Syngap1 in mice is correlated with increased steady-state levels of other key PSD proteins that ...
Basu, Shinjini, Chattarji, Sumantra, Kennedy, Mary B., Kind, Peter C., Mastro, Tara L., Preza, Anthony, Till, Sally M.   +6 more
core   +3 more sources

Electrospun Nanofibers and their Application in Tissue Repair and Engineering

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2020
Introduction: Tissue engineering is the repair and replacement of damaged tissues and requires a combination of cells, growth factor and porous scaffolds.
Sareh Arjmand, Alireza Partovi Baghdadeh, Amin Hamidi, Seyed Omid Ranaei Siadat   +3 more
doaj  

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Effectiveness of 2D fingerprints for scaffold hopping

, 2011
Background: It has been suggested that similarity searching using 2D fingerprints may not be suitable for scaffold hopping. Methods: This article reports a detailed evaluation of the effectiveness of six common types of 2D fingerprints when they are used
Gardiner, E.J., Holliday, J.D., O'Dowd, C., Willett, P.   +3 more
core   +1 more source

Inorganic nanowires [PDF]

, 2014
Provided in one embodiment is a method of forming an inorganic nanowire, comprising: providing an elongated organic scaffold; providing a plurality of inorganic nanoparticles attached to the organic scaffold along a length of the organic scaffold; and ...
Belcher, Angela M., Mao, Chuanbin, Solis, Daniel J.   +2 more
core   +1 more source