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The ECM: To Scaffold, or Not to Scaffold, That Is the Question [PDF]
International Journal of Molecular Sciences, 2021 The extracellular matrix (ECM) has pleiotropic effects, ranging from cell adhesion to cell survival. In tissue engineering, the use of ECM and ECM-like scaffolds has separated the field into two distinct areas—scaffold-based and scaffold-free. Scaffold-free techniques are used in creating reproducible cell aggregates which have massive potential for ...
Jonard Corpuz Valdoz +7 more
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Carbonate apatite nanoparticles: A novel nano-adjuvant for oral mucosal vaccines and immunomodulator
OpenNano, 2023 Vaccines manufacture and enhancement for preventing infection and promoting quality of life are of great concern worldwide. For vaccine enhancement, to date, only limited adjuvants have been approved globally.
Andari Sarasati +2 more
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Downregulation of stromal syntenin sustains AML development
EMBO Molecular Medicine, 2023 The crosstalk between cancer and stromal cells plays a critical role in tumor progression. Syntenin is a small scaffold protein involved in the regulation of intercellular communication that is emerging as a target for cancer therapy.
Raphael Leblanc +16 more
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Polysaccharides, 2022 In this study, chitosan and collagen (Ch: Col)-based materials containing curcumin (Cur) as a bioactive compound were developed for wound-healing purposes.
Eduardo P. Milan +4 more
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ERK Signals: Scaffolding Scaffolds? [PDF]
Frontiers in Cell and Developmental Biology, 2016 ERK1/2 MAP Kinases become activated in response to multiple intra- and extra-cellular stimuli through a signaling module composed of sequential tiers of cytoplasmic kinases. Scaffold proteins regulate ERK signals by connecting the different components of the module into a multi-enzymatic complex by which signal amplitude and duration are fine-tuned ...
Casar, Berta, Crespo, Piero
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Osteogenesis Improvement of Gelatin-Based Nanocomposite Scaffold by Loading Zoledronic Acid
Frontiers in Bioengineering and Biotechnology, 2022 Bisphosphonates (BPs) such as Zoledronic acid (ZA) are a subset of synthetic small molecules, which are now marketed as the main drugs to stimulate the growth and differentiation of osteoblast cells, thereby increasing bone formation as well as ...
Sayed Behnam Abdulahy +4 more
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Frontiers in Bioengineering and Biotechnology, 2021 Bone regeneration or replacement has been proved to be one of the most effective methods available for the treatment of bone defects caused by different musculoskeletal disorders.
Junyao Cheng +9 more
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The Scaffold Tree − Visualization of the Scaffold Universe by Hierarchical Scaffold Classification [PDF]
Journal of Chemical Information and Modeling, 2006 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Ansgar, Schuffenhauer +5 more
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Gels, 2022 In the present day, the increment in life expectancy has led to the necessity of developing new biomaterials for the restoration or substitution of damaged organs that have lost their functionalities.
Juan Pablo Fernández-Hernán +3 more
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Scaffolder - software for manual genome scaffolding [PDF]
Source Code for Biology and Medicine, 2012 The assembly of next-generation short-read sequencing data can result in a fragmented non-contiguous set of genomic sequences. Therefore a common step in a genome project is to join neighbouring sequence regions together and fill gaps. This scaffolding step is non-trivial and requires manually editing large blocks of nucleotide sequence.
Barton, Michael D, Barton, Hazel A
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