Results 21 to 30 of about 222,566 (219)

Energy Efficiency of the Carbonate Hydroxyapatite Nanoparticle Synthesis Using Microwave Heating Treatment and Its Effect on Material Characteristics

Indonesian Journal of Chemistry
This work aimed to study the energy efficiency of the synthesis process of carbonated hydroxyapatite (CHA) nanoparticles using microwave heating treatment and its effect on material characteristics.
Saifuddin Aziz, Harno Dwi Pranowo, Ika Dewi Ana, Yusril Yusuf   +3 more
doaj   +1 more source

The Expanded Role of Chitosan in Localized Antimicrobial Therapy

Marine Drugs, 2021
Chitosan is one of the most studied natural origin polymers for biomedical applications. This review focuses on the potential of chitosan in localized antimicrobial therapy to address the challenges of current rising antimicrobial resistance.
Lisa Myrseth Hemmingsen, Nataša Škalko-Basnet, May Wenche Jøraholmen   +2 more
doaj   +1 more source

CaSiO₃-HAp Metal-Reinforced Biocomposite Ceramics for Bone Tissue Engineering

Journal of Functional Biomaterials, 2023
Reconstructive and regenerative bone surgery is based on the use of high-tech biocompatible implants needed to restore the functions of the musculoskeletal system of patients.
Evgeniy K. Papynov, Oleg O. Shichalin, Anton A. Belov, Igor Yu Buravlev, Vitaly Yu Mayorov, Alexander N. Fedorets, Anastasiya A. Buravleva, Alexey O. Lembikov, Danila V. Gritsuk, Olesya V. Kapustina, Zlata E. Kornakova   +10 more
doaj   +1 more source

Crosslinked Silk Fibroin/Gelatin/Hyaluronan Blends as Scaffolds for Cell-Based Tissue Engineering

Molecules, 2021
3D porous scaffolds fabricated from binary and ternary blends of silk fibroin (SF), gelatin (G), and hyaluronan (HA) and crosslinked by the carbodiimide coupling reaction were developed.
Anongnart Duangpakdee, Chavee Laomeephol, Depicha Jindatip, Peerapat Thongnuek, Juthamas Ratanavaraporn, Siriporn Damrongsakkul   +5 more
doaj   +1 more source

Resembling mesenchymal stem cell microenvironment with growth factors loaded synthetic coral matrix for bone tissue engineering

Results in Engineering
The important factor in the design and realization of tissue engineering is the structure of three-dimensional (3D) synthetic scaffold that functions as synthetic extracellular matrix (ECM) which mimicking natural cell environment and preserve bioactive ...
Erlina Sih Mahanani, Ika Dewi Ana, Indra Bachtiar, Yin Xiao   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Development of a tissue-engineered oral mucosal barrier model using poly (l-lactic acid) electrospun nanofibers

Scientific Reports
The oral mucosa is a crucial barrier that defends against external factors and regulates tissue permeability. To advance trans-epithelial drug delivery and dental biomaterials research, a robust in vitro model of oral mucosal tissue is needed. This study
Andari Sarasati, Deniz Yucel, Halime Kenar, Hevi Wihadmadyatami, Neval Sevinc Ozdemir, Rahmi Anggraeni, Vasif Hasirci, Ika Dewi Ana   +7 more
doaj   +1 more source

Tissue-engineered repair material for pelvic floor dysfunction

Frontiers in Bioengineering and Biotechnology, 2022
Pelvic floor dysfunction (PFD) is a highly prevalent urogynecology disorder affecting many women worldwide, with symptoms including pelvic organ prolapse (POP), stress urinary incontinence (SUI), fecal incontinence, and overactive bladder syndrome (OAB).
Meina Lin, Yongping Lu, Jing Chen
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source