Results 131 to 140 of about 292,024 (345)

On the scalar curvature for the noncommutative four torus [PDF]

open access: yesJournal of Mathematical Physics, 2015
The scalar curvature for noncommutative four tori TΘ4, where their flat geometries are conformally perturbed by a Weyl factor, is computed by making the use of a noncommutative residue that involves integration over the 3-sphere. This method is more convenient since it does not require the rearrangement lemma and it is advantageous as it explains the ...
openaire   +7 more sources

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1926-1940, December 2022., 2022
Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh   +5 more
wiley   +1 more source

S- and T-self-dualities in dilatonic $$f(R)$$ f ( R ) theories

open access: yesEuropean Physical Journal C: Particles and Fields, 2017
We search for theories, in general spacetime dimensions, that would incorporate a dilaton and higher powers of the scalar Ricci curvature such that they have exact S- or T-self-dualities. The theories we find are free of Ostrogradsky instabilities.
Tonguç Rador
doaj   +1 more source

Scalar curvatures of Hermitian metrics on the moduli space of Riemann surfaces

open access: yes, 2015
In this article we show that any finite cover of the moduli space of closed Riemann surfaces of $g$ genus with $g\geq 2$ does not admit any complete finite-volume Hermitian metric of non-negative scalar curvature.
Wu, Yunhui
core  

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

Brain magnetic resonance imaging predictors in anti‐N‐methyl‐D‐aspartate receptor encephalitis

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1974-1984, December 2022., 2022
Abstract Objective Brain magnetic resonance imaging (MRI) findings in anti‐N‐methyl‐D‐aspartate receptor (NMDAR) encephalitis are nonspecific and rarely have obvious associations with clinical characteristics and outcomes. This study aimed to comprehensively describe the MRI features of patients with NMDAR encephalitis, examine their associations with ...
Ying‐Ying Zhao   +8 more
wiley   +1 more source

Effective Gravitational “Constant” in Scalar-(Curvature)Tensor and Scalar-Torsion Gravities

open access: yesUniverse, 2017
In theories where a scalar field couples nonminimally to gravity, the effective gravitational “constant” becomes dependent on the value of the scalar field.
Laur Järv
doaj   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

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