Results 131 to 140 of about 681,612 (344)

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

A geometric formulation of Higgs Effective Field Theory: Measuring the curvature of scalar field space

open access: yesPhysics Letters B, 2016
A geometric formulation of Higgs Effective Field Theory (HEFT) is presented. Experimental observables are given in terms of geometric invariants of the scalar sigma model sector such as the curvature of the scalar field manifold M.
Rodrigo Alonso   +2 more
doaj   +1 more source

Positive scalar curvature with symmetry

open access: yesJournal für die reine und angewandte Mathematik (Crelles Journal), 2008
36 pages, 1 figure, minor changes; to appear in J.
openaire   +3 more sources

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Inequality for Ricci curvature of certain submanifolds in locally conformal almost cosymplectic manifolds

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2005
We establish inequalities between the Ricci curvature and the squared mean curvature, and also between the k-Ricci curvature and the scalar curvature for a slant, semi-slant, and bi-slant submanifold in a locally conformal almost cosymplectic manifold ...
Dae Won Yoon
doaj   +1 more source

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

open access: yesMolecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul   +11 more
wiley   +1 more source

Thermodynamic geometry of holographic superconductors

open access: yesPhysics Letters B, 2016
We obtain the thermodynamic geometry of a (2+1) dimensional strongly coupled quantum field theory at a finite temperature in a holographic setup, through the gauge/gravity correspondence.
Sayan Basak   +3 more
doaj   +1 more source

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