Results 141 to 150 of about 192,579 (307)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source
A Note on Randers Metrics of Scalar Flag Curvature [PDF]
, 2011 Bin Chen, Lili Zhao
openalex +1 more source
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
FEBS Open Bio, EarlyView.The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
Einstein like -para Sasakian manifolds
Kuwait Journal of Science, 2013 Einstein like -para Sasakian manifolds are introduced. For an -para Sasakian manifold to be Einstein like, a necessary and sufficient condition in terms of its curvature tensor is obtained.
SADIK KELES +3 more
doaj
On manifolds with almost non-negative Ricci curvature and integrally-positive $k^{th}$-scalar curvature [PDF]
Alessandro Cucinotta, Andrea Mondino
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Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe
FEBS Open Bio, EarlyView.Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley +1 more source
Scalar Curvature Operator for Loop Quantum Gravity on a Cubical Graph
, 2023 Ilkka Mäkinen
openalex +1 more source
Singular scalar curvature equations
, 2022 We develop estimates for the equation of scalar curvature of singular metrics with cone angle $\beta>1$, in a big and semi-positive cohomology class on a K\"ahler manifold. We further derive the Laplacian estimate for the scalar curvature equation of degenerate K\"ahler metrics.
openaire +1 more source