Results 91 to 100 of about 680,116 (340)
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Zeta-nonlocal scalar fields [PDF]
Theoretical and Mathematical Physics, 2008 We consider some nonlocal and nonpolynomial scalar field models originated from p-adic string theory. Infinite number of spacetime derivatives is determined by the operator valued Riemann zeta function through d'Alembertian $\Box$ in its argument. Construction of the corresponding Lagrangians L starts with the exact Lagrangian $\mathcal{L}_p$ for ...
openaire +2 more sources
New scalar field quartessence [PDF]
Journal of Cosmology and Astroparticle Physics, 2019 Comment: 6 ...
Brandenberger, Robert +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
European Physical Journal C: Particles and Fields, 2019 We show that a canonical, minimally coupled scalar field which is non-self interacting and massless is equivalent to a null dust fluid (whether it is a test or a gravitating field), in a spacetime region in which its gradient is null.
Valerio Faraoni, Jeremy Côté
doaj +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Torsion, Dirac Field, Dark Matter and Dark Radiation
, 2006 The role of torsion and a scalar field $\phi$ in gravitation, especially, in the presence of a Dirac field in the background of a particular class of the Riemann-Cartan geometry is considered here. Recently, a Lagrangian density with Lagrange multipliers
Bandyopadhyay P. +8 more
core +3 more sources
Black holes and scalar fields [PDF]
Classical and Quantum Gravity, 2015 No-hair theorems in theories of gravity with a scalar field are briefly and critically reviewed. Their significance and limitations are discussed and potential evasions are considered.
openaire +3 more sources
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Turbulent Mixing in Transverse Jets [PDF]
, 2001 Turbulent mixing is studied in liquid-phase transverse jets. Jet-fluid concentration fields were measured using laser-induced fluorescence and digital-imaging techniques, for jets in the Reynolds number range 1000
Dimotakis, Paul, Shan, Jerry
core