Results 91 to 100 of about 8,907,785 (301)
The Geologic Time Scale: The Development of Life through time [PDF]
This text assists in understanding time relationships and how life on Earth has changed over time. The dates shown were compiled from several available sources.
core +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Specification, siting and selection of large WECS prototypes [PDF]
, 1979 The development of large-scale windpowered systems is outlined. Topics discussed include: prototype specifications development, site selection process, and selection of prototype ...
Hugossor, S.
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Wendy Syndrome as “Super Mother”: A Scale Development
Hayef: Journal of EducationWendy syndrome is a very common situation in the society. Wendy syndrome describes women who acted as mother to their husbands or people close to them. In order to develop the Wendy Syndrome Scale, data were collected from 666 women older than 18 years ...
Melek DEMIR, Meryem VURAL BATIK
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
CSM Testbed Development and Large-Scale Structural Applications [PDF]
A research activity called Computational Structural Mechanics (CSM) conducted at the NASA Langley Research Center is described. This activity is developing advanced structural analysis and computational methods that exploit high-performance computers ...
Gillian, R. E. +6 more
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Development of Social Sensitivity Scale
Hayef: Journal of Education, 2021 Faruk BOZDAĞ, Sabiha BOZDAĞ
doaj +1 more source
PSCP Cognitive Engagement Scale: A Scale Development Study
Educational Academic ResearchThis study aimed to develop and validate an instrument to measure students' cognitive engagement in teaching-learning environments. An exploratory correlational method was employed to develop the scale. 446 university pre‐degree students learning English
Seval Fer, Filiz Özek
doaj +1 more source