Results 71 to 80 of about 3,374,770 (347)

Neural parameter calibration for large-scale multi-agent models [PDF]

, 2022
Thomas A. Gaskin, Grigorios A. Pavliotis, Mark Girolami   +2 more
openalex   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Hypothesis tests on the scale parameter using median ranked set sampling

Statistica, 2008
In this paper, some test procedures for scale parameters of exponential and rectangular distributions involving the median ranked set sampling (MRSS) method are discussed. The necessary tables for the critical regions for the suggested tests are supplied.
Syed S. Hossain, Hassen A. Muttlak
doaj   +1 more source

A-posteriori error estimates for the localized reduced basis multi-scale method

, 2014
We present a localized a-posteriori error estimate for the localized reduced basis multi-scale (LRBMS) method [Albrecht, Haasdonk, Kaulmann, Ohlberger (2012): The localized reduced basis multiscale method].
Ohlberger, Mario, Schindler, Felix
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Investigation of scale parameter for the Weibull-Chen distribution

Research in Statistics
Within this article, we estimate the scale parameter for the Weibull-Chen distribution and calculate posterior distributions. This analysis involves the application of the Bayesian technique, which utilizes two non-informative priors along with three ...
Mohamed Mubarak, Fathy H. Riad
doaj   +1 more source

Sequential Point Estimation of a Function of the Exponential Scale Parameter

Austrian Journal of Statistics, 2016
We consider sequential point estimation of a function of the scale parameter of an exponential distribution subject to the loss function given as a sum of the squared error and a linear cost.
Chikara Uno, Eiichi Isogai, Daisy Lou Lim   +2 more
doaj   +1 more source

Vacuum stability in the singlet Majoron model

, 1994
We study the vacuum stability of the singlet Majoron model using full renormalization group improved scalar potential and Monte Carlo techniques. We show that in the perturbative regime of the various free parameters, the vacuum stability requirement ...
Bochkarev, Chikashige, Enqvist, Flores, Flores, Georgi, I. Vilja, J. Sirkka, Klinkhamer, Komatsu, Kondo, Kuzmin, Manton, Mori, Shaposnikov, Shaposnikov, Sher, Sher, Vilja   +18 more
core   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Sequential point and interval estimation of scale parameter of exponential distribution

International Journal of Mathematics and Mathematical Sciences, 1995
Sequential fixed-width confidence intervals are obtained for the scale parameter σ when the location parameter θ of the negative exponential distribution is unknown.
Z. Govindarajulu
doaj   +1 more source