Results 41 to 50 of about 2,580 (206)

Theoretical Analysis and Simulation of SiO2 and ZrO2 Based Antireflective Coatings to Improve Crystalline Silicon Solar Cell Efficiency

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi
The Solar cell efficiency is crucial, and optical losses can hinder it significantly. Anti-reflective coatings are effective in minimizing these losses.
İmran Kanmaz
doaj   +1 more source

Effect of copper oxide nanoparticles and light-emitting diode irradiation on the cell viability and osteogenic/odontogenic differentiation of human stem cells from the apical papilla

BMC Oral Health, 2023
Objectives This experimental study aimed to assess the effect of copper oxide nanoparticles (CuONPs) and light-emitting diode (LED) irradiation on the cell viability and osteogenic/odontogenic differentiation of human SCAPs.
Hamed Karkehabadi, Afsaneh Rahmati, Roshanak Abbasi, Abbas Farmany, Rezvan Najafi, Rooholah Behroozi, Loghman Rezaei-soufi, Hadiseh Abbaspourrokni   +7 more
doaj   +1 more source

To Assess the Cell Viability of Triple Antibiotic Paste under Confocal Microscope: An In Vitro Study [PDF]

Journal of South Asian Association of Pediatric Dentistry
Background and aim: Regenerative endodontic procedures (REPs) rely on the viability of stem cells from the apical papilla (SCAPs) to promote tissue repair and regeneration in immature teeth.
Elanthendral Saravanan, Mahesh Ramakrishnan   +1 more
doaj   +1 more source

Comparative Secretome Analysis of Mesenchymal Stem Cells From Dental Apical Papilla and Bone Marrow During Early Odonto/Osteogenic Differentiation: Potential Role of Transforming Growth Factor-β2

Frontiers in Physiology, 2020
To understand the functions of secretory proteins in odontogenesis and to further the understanding of the different molecular events during odontogenesis and osteogenesis, we induced the odonto/osteogenic differentiation of stem cells from dental apical
Shi Yu, Jingzhi Li, Yuming Zhao, Xiaoxia Li, Lihong Ge   +4 more
doaj   +1 more source

Retrospective on Cholesterol Homeostasis: The Central Role of Scap [PDF]

Annual Review of Biochemistry, 2018
Scap is a polytopic membrane protein that functions as a molecular machine to control the cholesterol content of membranes in mammalian cells. In the 21 years since our laboratory discovered Scap, we have learned how it binds sterol regulatory element-binding proteins (SREBPs) and transports them from the endoplasmic reticulum (ER) to the Golgi for ...
Michael S, Brown, Arun, Radhakrishnan, Joseph L, Goldstein   +2 more
openaire   +2 more sources

Functional Suppression of SCAP Triggers Endoplasmic Reticulum Stress‐Dependent Ferroptosis by Impairing Cholesterol Metabolism in Gastric Cancer

Advanced Science, EarlyView.
This study reveals a novel GC therapy targeting cholesterol homeostasis. Inhibiting the SCAP sterol‐sensing domain causes lethal ER stress via cholesterol accumulation, paradoxically forcing continuous synthesis that triggers ferroptosis. The findings link sterol sensing, metabolic dysregulation, and ferroptosis, establishing an anti‐cancer paradigm ...
Qianqian Xu, Guangzhao Pan, Lele Zhang, Xiangliu Chen, Kui Zhang, Yang Lu, Zibo Duan, Aiping Chen, Hailong Shen, Yuxi Zhang, Xiaowu Dong, Jinzhou Huang, Xing Huang, Kai Miao, Qian Hua, Fangfang Tao, Weidong Zhang, Jiang‐Jiang Qin   +17 more
wiley   +1 more source

Effects of decellularized extracellular matrix derived from Jagged1-treated human dental pulp stem cells on biological responses of stem cells isolated from apical papilla

Frontiers in Cell and Developmental Biology, 2022
Objective: Indirect Jagged1 immobilization efficiently activates canonical Notch signaling in human dental pulp stem cells (hDPSCs). This study aimed to investigate the characteristics of the Jagged1-treated hDPSC-derived decellularized extracellular ...
Suphalak Phothichailert, Nunthawan Nowwarote, Nunthawan Nowwarote, Benjamin P.J. Fournier, Benjamin P.J. Fournier, Vorapat Trachoo, Sittiruk Roytrakul, Worachat Namangkalakul, Thanaphum Osathanon, Thanaphum Osathanon   +9 more
doaj   +1 more source

HMGCR‐Driven Cholesterol Metabolism Promotes Osteoarthritis Progression by Accelerating Synovial Fibroblast Senescence

Advanced Science, EarlyView.
In the pathological context of osteoarthritis (OA), the phosphorylation of AKT1 at Ser473 enhances its binding to Lys140 of Insig1, which facilitates the formation of AKT1–Insig1 complex. Subsequently, the activation of AKT1 promotes the phosphorylation of Insig1 at Ser189, potentially enhancing the dissociation of Insig1 from sterol regulatory element‑
Xiaoqi Zhang, Siru Zhou, Xi Liu, Wei Xiang, Xiuqin Peng, Yu Tian, Song Li, Hailin Wang, Bo Liao, Shunzheng Fang, Runze Jin, Jinhui Wu, Chuanqing Bai, Wei Zhang, Bo Huang, Bingfei Li, Lifeng Chen, Lin Chen, Bin Zhang, Zhenhong Ni   +19 more
wiley   +1 more source

Scaps: type-directed API search for Scala [PDF]

Proceedings of the 2016 7th ACM SIGPLAN Symposium on Scala, 2016
Type-directed API search, using queries composed of both keywords and type signatures to retrieve definitions from APIs, are popular in the functional programming community. This search technique allows programmers to easily navigate complex and large APIs in order to find the definitions they are interested in.
Lukas Wegmann, Farhad Mehta, Peter Sommerlad, Mirko Stocker   +3 more
openaire   +1 more source

Gαi1/3 Are Essential for BMP2‐Induced Osteogenesis by Bridging BMP Receptors to the Gab1 Signaling Complex

Advanced Science, EarlyView.
The Gαi1/3 protein is a crucial connecting protein closely related to the signal transduction process of bone formation‐related cytokines such as BMP2. Gαi1/3 mediates downstream signaling pathways such as Smads and MAPK by binding to adaptor proteins like Gab1, thereby promoting the osteogenic effect of BMSCs.
Huajian Shan, Chaowen Bai, Yifei Zhu, Chenyang Xu, Sonngtao Li, Qize Sun, Chang She, Jinyu Bai, Cong Cao, Yitian Yang, Xiaozhong Zhou   +10 more
wiley   +1 more source