Results 1 to 10 of about 125 (95)

Stem Cells from the Apical Papilla (SCAPs): Past, Present, Prospects, and Challenges

Biomedicines, 2023
Dental diseases occurring on young permanent teeth usually lead to the premature arrest of tooth root development. Sustained tooth root elongation is necessary to achieve the goal of long-term preservation of affected teeth.
Qi Liu, Yuan Gao, Jinzhi He
doaj   +5 more sources

Stem Cells From the Apical Papilla (SCAP) as a Tool for Endogenous Tissue Regeneration [PDF]

Frontiers in Bioengineering and Biotechnology, 2018
Stem cells extracted from developing tissues possibly exhibit not only unique but also superior traits against their developed counterparts. Indeed, stem cells from the apical papilla (SCAP); a unique group of dental stem cells related to developing roots have been shown to be a promising tool for regenerative endodontic procedures and regeneration in ...
Ola A Nada, Rania El Backly
exaly   +4 more sources

The Journey of SCAPs (Stem Cells from Apical Papilla), from Their Native Tissue to Grafting: Impact of Oxygen Concentration

Cells, 2022
Tissue engineering strategies aim at characterizing and at optimizing the cellular component that is combined with biomaterials, for improved tissue regeneration.
Marine Mavinga, Mathilde Palmier, Murielle Rémy, Caroline Jeannière, Solène Lenoir, Sylvie Rey, Martine Saint-Marc, Florian Alonso, Elisabeth Génot, Noélie Thébaud, Edith Chevret, Virginie Mournetas, Benoit Rousseau, Claudine Boiziau, Helene Boeuf   +14 more
doaj   +5 more sources

Differential expression of Notch related genes in dental pulp stem cells and stem cells isolated from apical papilla

Journal of Oral Biology and Craniofacial Research, 2021
Although dental pulp and apical papilla are originated from neural crest cells, these tissues exhibit distinct characteristics. Notch signaling is one of the known signaling pathways regulating stemness and behaviors of stem cells.
Damrong Damrongsri, Nunthawan Nowwarote, Opor Sonpoung, Suphalak Photichailert, Thanaphum Osathanon   +4 more
doaj   +3 more sources

Exploring the potential of stem cells from the apical papilla (SCAPs) in regenerative medicine: advantages, applications, challenges and opportunities

Stem Cell Research & Therapy
Stem cells from the apical papilla (SCAPs) represent a unique population of mesenchymal stem cells (MSCs) located in the apical papilla of immature permanent teeth.
Mengyu Huang, Waruna Lakmal Dissanayaka, Cynthia KY YIU   +2 more
doaj   +3 more sources

Effect of Long-Term Cryopreservation on the Stemness of Stem Cells of Apical Papilla

International Journal of Dentistry, 2022
Stem cells of apical papilla (SCAPs) are considered a subpopulation of dental stem cells with unique properties. They originate from a developing tissue, the apical papilla of developing teeth, a characteristic that enhances their stemness.
Anna Digka, Eleni Gounari, Kokkona Kouzi-Koliakou, Kleoniki Lyroudia   +3 more
doaj   +1 more source

Establishing and characterizing human stem cells from the apical papilla immortalized by hTERT gene transfer

Frontiers in Cell and Developmental Biology, 2023
Stem cells from the apical papilla (SCAPs) are promising candidates for regenerative endodontic treatment and tissue regeneration in general. However, harvesting enough cells from the limited apical papilla tissue is difficult, and the cells lose their ...
Qianyu Cheng, Qianyu Cheng, Qianyu Cheng, Qianyu Cheng, Chang Liu, Chang Liu, Chang Liu, Chang Liu, Qiuman Chen, Wenping Luo, Tong-Chuan He, Deqin Yang, Deqin Yang, Deqin Yang, Deqin Yang   +14 more
doaj   +1 more source

Extracellular vesicles delivering nuclear factor I/C for hard tissue engineering: Treatment of apical periodontitis and dentin regeneration

Journal of Tissue Engineering, 2022
Apical periodontitis (AP) causes arrest of tooth root development, which is associated with impaired odontoblastic differentiation of stem cells from apical papilla (SCAPs), but the underlying mechanism remains unclear.
Shengyan Yang, Qing Liu, Shijing Chen, Fuping Zhang, Yaoyin Li, Wenguo Fan, Lijia Mai, Hongwen He, Fang Huang   +8 more
doaj   +1 more source

Combination of Dental Capping Agents With LowLevel Laser Therapy Increases the Cell Viability Percent of Stem Cells From Apical Papilla (SCAPs)

Journal of Lasers in Medical Sciences, 2022
Introduction: Dental pulp capping is a technique that is highly applicable in dental restorations. In this technique, a material is directly placed over the exposed pulp tissue, which promotes pulp healing and generates reparative dentin. Herein, we aimed to investigate the combined effect of different pulp capping agents, including mineral trioxide ...
Jaber, Zafari, Hamed, Karkehabadi, Forough, Nikzad, Sogand, Esmailnasab, Zahra, Abbasi Javan, Fatemeh, Javani Jouni   +5 more
openaire   +2 more sources

Gelatin–Chitosan Hydrogel Biological, Antimicrobial and Mechanical Properties for Dental Applications

Biomimetics, 2023
Chitosan, a natural polysaccharide sourced from crustaceans and insects, is often used with hydrogels in wound care. Evaluating its cytotoxicity and antimicrobial properties is crucial for its potential use in dentistry.
Andrea Itzamantul Flores-Espinoza, Rene Garcia-Contreras, Dulce Araceli Guzman-Rocha, Benjamin Aranda-Herrera, Patricia Alejandra Chavez-Granados, Carlos A. Jurado, Yasser F. Alfawaz, Abdulrahman Alshabib   +7 more
doaj   +1 more source