Results 1 to 10 of about 1,289 (174)

Combination of Dental Capping Agents With LowLevel Laser Therapy Increases the Cell Viability Percent of Stem Cells From Apical Papilla (SCAPs). [PDF]

J Lasers Med Sci, 2022
Introduction: Dental pulp capping is a technique that is highly applicable in dental restorations. In this technique, a material is directly placed over the exposed pulp tissue, which promotes pulp healing and generates reparative dentin. Herein, we aimed to investigate the combined effect of different pulp capping agents, including mineral trioxide ...
Zafari J, Karkehabadi H, Nikzad F, Esmailnasab S, Abbasi Javan Z, Javani Jouni F.   +5 more
europepmc   +6 more sources

Stem Cells from the Apical Papilla (SCAPs): Past, Present, Prospects, and Challenges

Biomedicines, 2023
Dental diseases occurring on young permanent teeth usually lead to the premature arrest of tooth root development. Sustained tooth root elongation is necessary to achieve the goal of long-term preservation of affected teeth.
Qi Liu, Yuan Gao, Jinzhi He
doaj   +5 more sources

Exploring the potential of stem cells from the apical papilla (SCAPs) in regenerative medicine: advantages, applications, challenges and opportunities [PDF]

Stem Cell Research & Therapy
Stem cells from the apical papilla (SCAPs) represent a unique population of mesenchymal stem cells (MSCs) located in the apical papilla of immature permanent teeth.
Mengyu Huang, Waruna Lakmal Dissanayaka, Cynthia KY YIU   +2 more
doaj   +3 more sources

The Journey of SCAPs (Stem Cells from Apical Papilla), from Their Native Tissue to Grafting: Impact of Oxygen Concentration [PDF]

Cells, 2022
Tissue engineering strategies aim at characterizing and at optimizing the cellular component that is combined with biomaterials, for improved tissue regeneration.
Marine Mavinga, Mathilde Palmier, Murielle Rémy, Caroline Jeannière, Solène Lenoir, Sylvie Rey, Martine Saint-Marc, Florian Alonso, Elisabeth Génot, Noélie Thébaud, Edith Chevret, Virginie Mournetas, Benoit Rousseau, Claudine Boiziau, Helene Boeuf   +14 more
doaj   +7 more sources

The Angiogenic Potential of DPSCs and SCAPs in an In Vivo Model of Dental Pulp Regeneration [PDF]

Stem Cells International, 2017
Adequate vascularization, a restricting factor for the survival of engineered tissues, is often promoted by the addition of stem cells or the appropriate angiogenic growth factors.
Petra Hilkens, Annelies Bronckaers, Jessica Ratajczak, Pascal Gervois, Esther Wolfs, Ivo Lambrichts   +5 more
doaj   +6 more sources

Establishing and characterizing human stem cells from the apical papilla immortalized by hTERT gene transfer [PDF]

Frontiers in Cell and Developmental Biology, 2023
Stem cells from the apical papilla (SCAPs) are promising candidates for regenerative endodontic treatment and tissue regeneration in general. However, harvesting enough cells from the limited apical papilla tissue is difficult, and the cells lose their ...
Qianyu Cheng, Qianyu Cheng, Qianyu Cheng, Qianyu Cheng, Chang Liu, Chang Liu, Chang Liu, Chang Liu, Qiuman Chen, Wenping Luo, Tong-Chuan He, Deqin Yang, Deqin Yang, Deqin Yang, Deqin Yang   +14 more
doaj   +3 more sources

Schisantherin A promotes neural differentiation of stem cells from apical papilla to improve mandibular development via mental nerve repair [PDF]

Stem Cell Research & Therapy
Background Evidence shows neural involvement in bone remodeling; regulating maxillofacial nerve repair modulates jawbone. Neural stem cell (NSC) therapy is limited by sources/ethics, but neural crest-derived dental mesenchymal stem cells (MSCs) like stem
Lingxi Du, Ailian Li, Ziling Tang, Hanxiang Yang, Xinyu Shi, Shengchao Wang, Zuocheng Qiu, Xuesong Yang, Yue Huang   +8 more
doaj   +2 more sources

Hypoxic stem cells from apical papilla-derived exosomes enhance dental pulp stem cells migration and differentiation via mitochondrial activation [PDF]

Journal of Dental Sciences
Background/purpose: Stem cells from apical papilla (SCAPs) and dental pulp stem cells (DPSCs) play critical roles in dental tissue regeneration. Although intercellular communication through exosomes is known to influence stem cell regulation, the effects
Deyan Yuan, Rui Tao, Bi Yin, Meng Gu
doaj   +2 more sources

Simvastatin modulates osteogenic differentiation in Stem Cells isolated from Apical Papilla [PDF]

BMC Oral Health
Background Simvastatin modulates numerous stem cell functions, including stemness maintenance and differentiation. The present study aimed to explore the effect of simvastatin on the osteogenic differentiation of Stem Cells isolated from Apical Papilla ...
Paak Rewthamrongsris, Suphalak Phothichailert, Uraiwan Chokechanachaisakul, Prim Janjarussakul, Chatvadee Kornsuthisopon, Lakshman Samaranayake, Thanaphum Osathanon   +6 more
doaj   +2 more sources

Lumican from DESC spheroids enhances odontoblastic differentiation of SCAPs [PDF]

Stem Cell Research & Therapy
Aim During the tooth-root elongation phase, dental epithelial stem cells (DESCs) cluster together and release various signaling molecules, facilitating the differentiation of stem cells from the apical papilla (SCAPs) into odontoblasts.
Qinyao Zhang, Shuwei Huang, Xiaoqian Liu, Meijiu Zhang, Jun Sun, Mingzhu Liu, Hemin Nie, Lei Lei   +7 more
doaj   +2 more sources