Results 41 to 50 of about 1,289 (174)

From biofilm disinfection to bacterial stem cell modulation and dentin matrix-driven stem cell mineralization [PDF]

, 2020
Caries or trauma are common occurrences in the permanent dentition of young patients. They often result in pulp necrosis, root canal infection, inflammation (apical periodontitis) and arrest of further root development.
Petridis, Xenos
core   +1 more source

Recent Advances in Apical Periodontitis Treatment: A Narrative Review [PDF]

, 2023
Apical periodontitis is an inflammatory response caused by pulp infection. It induces bone resorption in the apical and periapical regions of the tooth. The most conservative approach to treat this condition is nonsurgical endodontic treatment.
Arias, Zulema, Chai, Xinyi, Chen, Xiaoting, Kuang, Canyan, Nizami, Mohammed Zahedul Islam, Omori, Kazuhiro, Takashiba, Shogo, Xu, Bin   +7 more
core   +1 more source

Circular RNA SIPA1L1 regulates osteoblastic differentiation of stem cells from apical papilla via miR-204-5p/ALPL pathway

Stem Cell Research & Therapy, 2020
Background Osteogenesis is a complex biological process which requires the coordination of multiple molecular mechanisms. This research aimed to explore the biological role and underlying regulatory mechanism of circSIPA1L1 during the osteogenic ...
Yuzhi Li, Minxia Bian, Zhou Zhou, Xiao Wu, Xingyun Ge, Tong Xiao, Jinhua Yu   +6 more
doaj   +1 more source

Epigallocatechin-3-Gallate Promotes Osteo-/Odontogenic Differentiation of Stem Cells from the Apical Papilla through Activating the BMP–Smad Signaling Pathway

Molecules, 2021
Stem cells from apical papilla (SCAPs) are desirable sources of dentin regeneration. Epigallocatechin-3-gallate (EGCG), a natural component of green tea, shows potential in promoting the osteogenic differentiation of bone mesenchymal stem cells. However,
Zeni Liu, Yuxiu Lin, Xiaolin Fang, Jingwen Yang, Zhi Chen   +4 more
doaj   +1 more source

Isolation and characterization of apical papilla cells from root end of human third molar and their differentiation into cementoblast cells: an in vitro study

Biological Procedures Online, 2023
Background Periodontal regeneration, treatment of periodontal-related diseases and improving the function of implants are global therapeutic challenges. The differentiation of human stem cells from apical papilla into cementoblasts may provide a strategy
Morvarid Ebadi, Amirfarhang Miresmaeili, Sarah Rajabi, Shahrokh Shojaei, Sareh Farhadi   +4 more
doaj   +1 more source

Isolation and Culture of Human Stem Cells from Apical Papilla under Low Oxygen Concentration Highlight Original Properties

Cells, 2019
: Stem cells isolated from the apical papilla of wisdom teeth (SCAPs) are an attractive model for tissue repair due to their availability, high proliferation rate and potential to differentiate in vitro towards mesodermal and neurogenic lineages.
Murielle Rémy, Francesca Ferraro, Pierre Le Salver, Sylvie Rey, Elisabeth Genot, Mojgan Djavaheri-Mergny, Noélie Thébaud, Claudine Boiziau, Hélène Boeuf   +8 more
doaj   +1 more source

DLX5 and HOXC8 enhance the chondrogenic differentiation potential of stem cells from apical papilla via LINC01013

Stem Cell Research & Therapy, 2020
Background Mesenchymal stem cell (MSC)-based cartilage tissue regeneration is a treatment with great potential. How to enhance the MSC chondrogenic differentiation is a key issue involved in cartilage formation.
Haoqing Yang, Yangyang Cao, Jianpeng Zhang, Yuncun Liang, Xiaomin Su, Chen Zhang, Huina Liu, Xiao Han, Lihua Ge, Zhipeng Fan   +9 more
doaj   +1 more source

A pilot study on biological characteristics of human CD24(+) stem cells from the apical papilla

Journal of Dental Sciences, 2022
Background/purpose: CD24 is a specific cell surface marker for undifferentiated dental stem cells from apical papilla (SCAPs) seen only during root development, before the tooth emerges through gum.
Jing Liang, Ya-Jin Zhao, Jun-Qing Li, Lan Lan, Wen-Jing Tao, Jia-Yuan Wu   +5 more
doaj   +1 more source

Cyclic Adenosine Monophosphate Promotes Odonto/Osteogenic Differentiation of Stem Cells from the Apical Papilla via Suppression of Transforming Growth Factor Beta 1 Signaling [PDF]

, 2019
Introduction: Stem cells from the apical papilla (SCAPs) possess strong odonto/osteogenic differentiation potential. This study investigated the effect of cyclic adenosine monophosphate (cAMP) on odonto/osteogenic differentiation of SCAPs and the ...
Chu, CH, Quan, LL, Zhang, C, Zhang, J
core   +1 more source

MLL1 inhibits the neurogenic potential of SCAPs by interacting with WDR5 and repressing HES1

International Journal of Oral Science, 2023
Mesenchymal stem cell (MSC)-based therapy has emerged as a promising treatment for spinal cord injury (SCI), but improving the neurogenic potential of MSCs remains a challenge.
Chen Zhang, Weilong Ye, Mengyao Zhao, Lujue Long, Dengsheng Xia, Zhipeng Fan   +5 more
doaj   +1 more source