Results 1 to 10 of about 3,788 (230)

Simvastatin Induces Apoptosis but Attenuates Migration in SCAPs

International Dental Journal
Simvastatin has emerged as having a promising role in controlling stem cell behaviours. This study aimed to evaluate the effects of simvastatin on the viability, growth, and migration of stem cells isolated from apical papillae (SCAPs) in vitro. SCAPs were isolated and characterised.
Paak Rewthamrongsris, Suphalak Phothichailert, Uraiwan Chokechanachaisakul, Chatvadee Kornsuthisopon, Thanaphum Osathanon   +4 more
openaire   +4 more sources

Study on the promotion of osteo/odontogenic differentiation on SCAPs and anti-inflammatory effects of EGCG/CeO2-loaded nanoparticles in an inflammatory microenvironment [PDF]

Kouqiang yixue
Objective To investigate the effects of composite nanoparticles E/Ce@MCSNs loaded with epigallocatechin-3-gallate (EGCG) and cerium dioxide (CeO2) on the odonto/osteogenic differentiation of human stem cells from the apical papilla (SCAPs) and macrophage
WU Yuting, DAI Mingrui, LENG Diya, ZHU Tingting, WU Tao, WU Daming
doaj   +2 more sources

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source

Accelerating Perovskite Solar Cell Development Through High‐Throughput Technologies: Computational Simulation, Automated Experimentation, and Intelligent Integration

Battery Energy, Volume 5, Issue 4, July 2026.
Moving beyond traditional trial‐and‐error, this review explores how integrating high‐throughput computational simulations, automated experimentation, and machine learning significantly accelerates perovskite solar cell development. By establishing intelligent, closed‐loop workflows, these synergistic technologies pave the way for fully autonomous ...
Yiming Wang, Ziwei Du, Yuhui Chen, Yicheng Qiu, Dong Yan, Bo Hou   +5 more
wiley   +1 more source

SCAP composer user guide

, 2020
SCAP Composer is a software application from the National Institute of Standards and Technology (NIST) for creating Security Content Automation Protocol (SCAP pronounced ess-cap) source data stream collections. A source data stream collection is a bundle of Extensible Markup Language (XML) documents, each of which must be valid with respect to a ...
openaire   +1 more source

The Efficacy of Intracanal Medicaments Within the Regenerative Endodontic Procedures on Permanent Necrotic Immature Teeth: Systematic Review and Naïve Indirect‐Comparison Meta‐Analysis

International Endodontic Journal, Volume 59, Issue 7, Page 1337-1357, July 2026.
ABSTRACT Objectives The objectives of this study were to estimate and compare the 1‐year clinical success rates of triple antibiotic paste (TAP), double antibiotic paste (DAP), calcium hydroxide (CH) within regenerative endodontic procedures (REPs) on permanent necrotic immature teeth.
Mario Alovisi, Paolo G. Arduino, Stefano Petti   +2 more
wiley   +1 more source

Competition between a transmembrane helix on Scap and a membrane cholesterol regulates Scap–Insig interaction and SREBP activation

Proceedings of the National Academy of Sciences
Cholesterol homeostasis in mammalian cells relies on the interaction between two endoplasmic reticulum (ER) sterol-sensing membrane proteins, Scap and Insig. Their interaction regulates activation of transcription factors called sterol regulatory element–binding proteins (SREBPs) that control genes for cholesterol biosynthesis and uptake.
Blake C. Williams, Daniel L. Kober, Xiao-chen Bai, Daniel M. Rosenbaum, Arun Radhakrishnan   +4 more
openaire   +3 more sources

3D culture inhibits replicative senescence of SCAPs via UQCRC2-mediated mitochondrial oxidative phosphorylation

Journal of Translational Medicine
Stem cells derived from the apical papilla (SCAPs) play a crucial role in tooth root development and dental pulp regeneration. They are important seed cells for bone/tooth tissue engineering.
Yijia Shi, Tong Xiao, Yingying Weng, Ya Xiao, Jintao Wu, Jing Wang, Wenmin Wang, Maoshen Yan, Ming Yan, Zehan Li, Jinhua Yu   +10 more
doaj   +1 more source

Reproductive Cycle of Marphysa sanguinea (Montagu, 1815) (Polychaeta: Eunicidae) in the Lagoon of Tunis

The Scientific World Journal, 2013
The reproductive cycle of Marphysa sanguinea (Polychaeta: Eunicidae) was studied in the Lagoon of Tunis between May 2006 and May 2007. M. sanguinea is a gonochoric species.
Monia El Barhoumi, Patrick Scaps, Fathia Zghal   +2 more
doaj   +1 more source