Results 21 to 30 of about 51,716,445 (167)

Inhibition of miR-615-3p enhances dentinogenesis in scaps via PVT1-mediated mitochondrial regulation [PDF]

Stem Cell Research & Therapy
Background Mesenchymal stem cells (MSCs) are critical for dental tissue regeneration, yet their differentiation potential is tightly regulated by microRNAs (miRNAs).
Haoqing Yang, Yishu Huang, Jiaxin Song, Xiao Han, Fengning Yuan, Zhipeng Fan   +5 more
doaj   +2 more sources

Sustained Mg/Sr ion delivery from injectable silk fibroin hydrogels drives SCAP osteogenic differentiation [PDF]

iScience
Summary: This study highlights the biomedical relevance of injectable TS (tannic acid-silk fibroin)-Mg/Sr hydrogels in alveolar bone repair, particularly their prospective role as carriers for stem cells from the apical papilla (SCAPs) in tissue ...
Chen Chen, Zhengrong Gao, Yuman Li, Tuanfeng Zhou, Huimin Zheng, Shengjie Jiang, Yue Yang, Yan Wei   +7 more
doaj   +2 more sources

Roles of basic fibroblast growth factor, stem cells from dental pulp and apical papilla in the repair and regeneration of dental pulp and other tissues/organs [PDF]

Journal of Dental Sciences
Currently, the concept of regeneration and regenerative therapies are already being applied clinically to treat pulpal and periodontal diseases, as well as to repair and regenerate systemic organs and tissues.
Pin-Hsuan Wu, Yan-Hsiung Wang, Ying-Chu Lin, Ya-Shuan Chou, Mei-Chi Chang, Jiiang-Huei Jeng   +5 more
doaj   +2 more sources

Exosomes derived from apical papilla stem cells improve NASH by regulating fatty acid metabolism and reducing inflammation

Molecular Medicine
Background Apical papilla stem cells (SCAPs) exhibit significant potential for tissue repair, characterized by their anti-inflammatory and pro-angiogenic properties.
Yifei Nie, Wenqing Meng, Duanqin Liu, Ziqing Yang, Wenhao Wang, Huiping Ren, Kai Mao, Weipeng Lan, Chuanhua Li, Zhifeng Wang, Jing Lan   +10 more
doaj   +2 more sources

Stem Cells From the Apical Papilla (SCAP) as a Tool for Endogenous Tissue Regeneration [PDF]

Frontiers in Bioengineering and Biotechnology, 2018
Stem cells extracted from developing tissues possibly exhibit not only unique but also superior traits against their developed counterparts. Indeed, stem cells from the apical papilla (SCAP); a unique group of dental stem cells related to developing roots have been shown to be a promising tool for regenerative endodontic procedures and regeneration in ...
Ola A. Nada, Ola A. Nada, Rania M. El Backly, Rania M. El Backly   +3 more
openaire   +3 more sources

Extracellular vesicles delivering nuclear factor I/C for hard tissue engineering: Treatment of apical periodontitis and dentin regeneration

Journal of Tissue Engineering, 2022
Apical periodontitis (AP) causes arrest of tooth root development, which is associated with impaired odontoblastic differentiation of stem cells from apical papilla (SCAPs), but the underlying mechanism remains unclear.
Shengyan Yang, Qing Liu, Shijing Chen, Fuping Zhang, Yaoyin Li, Wenguo Fan, Lijia Mai, Hongwen He, Fang Huang   +8 more
doaj   +1 more source

Gelatin–Chitosan Hydrogel Biological, Antimicrobial and Mechanical Properties for Dental Applications

Biomimetics, 2023
Chitosan, a natural polysaccharide sourced from crustaceans and insects, is often used with hydrogels in wound care. Evaluating its cytotoxicity and antimicrobial properties is crucial for its potential use in dentistry.
Andrea Itzamantul Flores-Espinoza, Rene Garcia-Contreras, Dulce Araceli Guzman-Rocha, Benjamin Aranda-Herrera, Patricia Alejandra Chavez-Granados, Carlos A. Jurado, Yasser F. Alfawaz, Abdulrahman Alshabib   +7 more
doaj   +1 more source

Translational and Clinical Applications of Dental Stem Cell-Derived Exosomes

Frontiers in Genetics, 2021
Mesenchymal stem cells (MSCs) are promising seed cells in tissue repair and regeneration due to their featured properties of self-renewal and multipotency.
Zizhao Mai, Huan Chen, Yu Ye, Yu Ye, Ziyu Hu, Wenjuan Sun, Li Cui, Li Cui, Xinyuan Zhao   +8 more
doaj   +1 more source

Enhancer of zeste homolog 2 enhances the migration and chemotaxis of dental mesenchymal stem cells

Journal of International Medical Research, 2020
Objective To investigate the function of enhancer of zeste homolog 2 (EZH2) in the migration and chemotaxis of human dental tissue-derived mesenchymal stem cells. Methods The expression of EZH2, C-X-C motif chemokine ligand 11 (CXCL11), CXCL16, and CXCR1
Huarui Ma, Shaoyu Duan, Fei Yan, Haoqing Yang, Yangyang Cao, Lihua Ge, Runtao Gao   +6 more
doaj   +1 more source

Evaluation of the Cytotoxicity of Two Types of Triple Antibiotic Paste on Human Permanent Dental Apical Papilla Stem Cells: an in vitro Study [PDF]

Journal of Dentistry, 2022
Statement of the Problem: The use of a new antimicrobial combination in the regenerative endodontic treatment of immature teeth pulp necrosis is a well-known method.
Rezvan Rafatjou , Arghavan Kamali Sabeti , Bahar Ahmadi , Sara Soleimani Asl , Maryam Farhadian   +4 more
doaj   +1 more source