Results 11 to 20 of about 125 (95)

Formation of Three-Dimensional Spheres Enhances the Neurogenic Potential of Stem Cells from Apical Papilla

open access: yesBioengineering, 2022
Cell-based neural regeneration is challenging due to the difficulty in obtaining sufficient neural stem cells with clinical applicability. Stem cells from apical papilla (SCAPs) originating from embryonic neural crests with high neurogenic potential ...
Mohammed S. Basabrain   +8 more
doaj   +1 more source

Enhancer of zeste homolog 2 enhances the migration and chemotaxis of dental mesenchymal stem cells

open access: yesJournal of International Medical Research, 2020
Objective To investigate the function of enhancer of zeste homolog 2 (EZH2) in the migration and chemotaxis of human dental tissue-derived mesenchymal stem cells. Methods The expression of EZH2, C-X-C motif chemokine ligand 11 (CXCL11), CXCL16, and CXCR1
Huarui Ma   +6 more
doaj   +1 more source

Translational and Clinical Applications of Dental Stem Cell-Derived Exosomes

open access: yesFrontiers in Genetics, 2021
Mesenchymal stem cells (MSCs) are promising seed cells in tissue repair and regeneration due to their featured properties of self-renewal and multipotency.
Zizhao Mai   +8 more
doaj   +1 more source

Evaluation of the Cytotoxicity of Two Types of Triple Antibiotic Paste on Human Permanent Dental Apical Papilla Stem Cells: an in vitro Study [PDF]

open access: yesJournal of Dentistry, 2022
Statement of the Problem: The use of a new antimicrobial combination in the regenerative endodontic treatment of immature teeth pulp necrosis is a well-known method.
Rezvan Rafatjou   +4 more
doaj   +1 more source

WIF1 enhanced dentinogenic differentiation in stem cells from apical papilla

open access: yesBMC Oral Health, 2019
Background Odontogenic mesenchymal stem cells (MSCs) isolated from tooth tissues are a reliable resource that can be utilized for dental tissue regeneration.
Haifeng Wang, Yu Cao
doaj   +1 more source

SFRP2 enhances the osteogenic differentiation of apical papilla stem cells by antagonizing the canonical WNT pathway

open access: yesCellular & Molecular Biology Letters, 2017
Background Exploring the molecular mechanisms underlying directed differentiation is helpful in the development of clinical applications of mesenchymal stem cells (MSCs).
Luyuan Jin   +12 more
doaj   +1 more source

Epigenetic regulation of dental-derived stem cells and their application in pulp and periodontal regeneration [PDF]

open access: yesPeerJ, 2023
Dental-derived stem cells have excellent proliferation ability and multi-directional differentiation potential, making them an important research target in tissue engineering.
Yuyang Chen   +4 more
doaj   +2 more sources

Circular RNA SIPA1L1 regulates osteoblastic differentiation of stem cells from apical papilla via miR-204-5p/ALPL pathway

open access: yesStem Cell Research & Therapy, 2020
Background Osteogenesis is a complex biological process which requires the coordination of multiple molecular mechanisms. This research aimed to explore the biological role and underlying regulatory mechanism of circSIPA1L1 during the osteogenic ...
Yuzhi Li   +6 more
doaj   +1 more source

Isolation and characterization of apical papilla cells from root end of human third molar and their differentiation into cementoblast cells: an in vitro study

open access: yesBiological Procedures Online, 2023
Background Periodontal regeneration, treatment of periodontal-related diseases and improving the function of implants are global therapeutic challenges. The differentiation of human stem cells from apical papilla into cementoblasts may provide a strategy
Morvarid Ebadi   +4 more
doaj   +1 more source

Isolation and Culture of Human Stem Cells from Apical Papilla under Low Oxygen Concentration Highlight Original Properties

open access: yesCells, 2019
: Stem cells isolated from the apical papilla of wisdom teeth (SCAPs) are an attractive model for tissue repair due to their availability, high proliferation rate and potential to differentiate in vitro towards mesodermal and neurogenic lineages.
Murielle Rémy   +8 more
doaj   +1 more source

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