Results 11 to 20 of about 51,716,445 (167)
Simvastatin modulates osteogenic differentiation in Stem Cells isolated from Apical Papilla [PDF]
BMC Oral HealthBackground Simvastatin modulates numerous stem cell functions, including stemness maintenance and differentiation. The present study aimed to explore the effect of simvastatin on the osteogenic differentiation of Stem Cells isolated from Apical Papilla ...
Paak Rewthamrongsris +6 more
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Effect of Long-Term Cryopreservation on the Stemness of Stem Cells of Apical Papilla
International Journal of Dentistry, 2022 Stem cells of apical papilla (SCAPs) are considered a subpopulation of dental stem cells with unique properties. They originate from a developing tissue, the apical papilla of developing teeth, a characteristic that enhances their stemness.
Anna Digka +3 more
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Establishing and characterizing human stem cells from the apical papilla immortalized by hTERT gene transfer [PDF]
Frontiers in Cell and Developmental Biology, 2023 Stem cells from the apical papilla (SCAPs) are promising candidates for regenerative endodontic treatment and tissue regeneration in general. However, harvesting enough cells from the limited apical papilla tissue is difficult, and the cells lose their ...
Qianyu Cheng +14 more
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WIF1 enhanced dentinogenic differentiation in stem cells from apical papilla
BMC Oral Health, 2019 Background Odontogenic mesenchymal stem cells (MSCs) isolated from tooth tissues are a reliable resource that can be utilized for dental tissue regeneration.
Haifeng Wang, Yu Cao
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Bioengineering, 2022 Cell-based neural regeneration is challenging due to the difficulty in obtaining sufficient neural stem cells with clinical applicability. Stem cells from apical papilla (SCAPs) originating from embryonic neural crests with high neurogenic potential ...
Mohammed S. Basabrain +8 more
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Isolation and Culture of Human Stem Cells from Apical Papilla under Low Oxygen Concentration Highlight Original Properties [PDF]
Cells, 2019 : Stem cells isolated from the apical papilla of wisdom teeth (SCAPs) are an attractive model for tissue repair due to their availability, high proliferation rate and potential to differentiate in vitro towards mesodermal and neurogenic lineages.
Murielle Rémy +8 more
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Cellular & Molecular Biology Letters, 2017 Background Exploring the molecular mechanisms underlying directed differentiation is helpful in the development of clinical applications of mesenchymal stem cells (MSCs).
Luyuan Jin +12 more
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Lumican from DESC spheroids enhances odontoblastic differentiation of SCAPs [PDF]
Stem Cell Research & TherapyAim During the tooth-root elongation phase, dental epithelial stem cells (DESCs) cluster together and release various signaling molecules, facilitating the differentiation of stem cells from the apical papilla (SCAPs) into odontoblasts.
Qinyao Zhang +7 more
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Research progress in heterogeneity of dental mesenchymal stem cells [PDF]
International Journal of Oral ScienceDental tissues development involves two distinct cell lineages: mesenchymal cells (derived from the cranial neural crest) and epithelial cells (derived from oral ectoderm and pharyngeal epithelium).
Hanqi Fu +9 more
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Stem Cells International, 2020 Understanding the regulation mechanisms of mesenchymal stem cells (MSCs) can assist in tissue regeneration. The histone demethylase (KDM) family has a crucial role in differentiation and cell proliferation of MSCs, while the function of KDM3B in MSCs is ...
Chen Zhang +5 more
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