Results 31 to 40 of about 51,716,445 (167)

Epigallocatechin-3-Gallate Promotes Osteo-/Odontogenic Differentiation of Stem Cells from the Apical Papilla through Activating the BMP–Smad Signaling Pathway

Molecules, 2021
Stem cells from apical papilla (SCAPs) are desirable sources of dentin regeneration. Epigallocatechin-3-gallate (EGCG), a natural component of green tea, shows potential in promoting the osteogenic differentiation of bone mesenchymal stem cells. However,
Zeni Liu, Yuxiu Lin, Xiaolin Fang, Jingwen Yang, Zhi Chen   +4 more
doaj   +1 more source

Epigenetic regulation of dental-derived stem cells and their application in pulp and periodontal regeneration [PDF]

PeerJ, 2023
Dental-derived stem cells have excellent proliferation ability and multi-directional differentiation potential, making them an important research target in tissue engineering.
Yuyang Chen, Xiayi Wang, Zhuoxuan Wu, Shiyu Jia, Mian Wan   +4 more
doaj   +2 more sources

Circular RNA SIPA1L1 regulates osteoblastic differentiation of stem cells from apical papilla via miR-204-5p/ALPL pathway

Stem Cell Research & Therapy, 2020
Background Osteogenesis is a complex biological process which requires the coordination of multiple molecular mechanisms. This research aimed to explore the biological role and underlying regulatory mechanism of circSIPA1L1 during the osteogenic ...
Yuzhi Li, Minxia Bian, Zhou Zhou, Xiao Wu, Xingyun Ge, Tong Xiao, Jinhua Yu   +6 more
doaj   +1 more source

Characterization of human apical papilla-derived stem cells

, 2022
Dental tissues represent an alternative and promising source of post-natal Mesenchymal stem cells (MSCs) for tissue engineering. Furthermore, dental stem cells from apical papilla (SCAPs) cells can be obtained from the wisdom tooth which is unnecessary ...
Inchingolo, F., Ballini, A., S. Martelli, F., Farronato, G., Cantore, S., Almasri, M., De Vito, D., Dibello, V., Georgakopoulos, I., Altini, V., Dipalma, G., Farronato, D.   +11 more
core   +1 more source

Isolation and characterization of apical papilla cells from root end of human third molar and their differentiation into cementoblast cells: an in vitro study

Biological Procedures Online, 2023
Background Periodontal regeneration, treatment of periodontal-related diseases and improving the function of implants are global therapeutic challenges. The differentiation of human stem cells from apical papilla into cementoblasts may provide a strategy
Morvarid Ebadi, Amirfarhang Miresmaeili, Sarah Rajabi, Shahrokh Shojaei, Sareh Farhadi   +4 more
doaj   +1 more source

Effects of ethylenediaminetetraacetic acid on stem cells from the apical papilla: In vitro study

, 2022
International audienceEthylenediaminetetraacetic acid (EDTA) is used as an irrigant in regenerative endodontic treatment. The present study aimed to investigate the effects of EDTA on stem cells from apical papilla (SCAPs) in vitro.Overall, SCAPs ...
Dhitinant Rattanakosol, Nutcha Teerapongpaibul, Phothichailert, Suphalak, Sangwisutsai, Benya, Osathanon, Thanaphum, Sirawut Hiran-us, Teerapongpaibul, Nutcha, Nowwarote, Nunthawan, Benya Sangwisutsai, Hiran-Us, Sirawut, Nunthawan Nowwarote, Rattanakosol, Dhitinant, Suphalak Phothichailert, Thanaphum Osathanon   +13 more
core   +1 more source

DLX5 and HOXC8 enhance the chondrogenic differentiation potential of stem cells from apical papilla via LINC01013

Stem Cell Research & Therapy, 2020
Background Mesenchymal stem cell (MSC)-based cartilage tissue regeneration is a treatment with great potential. How to enhance the MSC chondrogenic differentiation is a key issue involved in cartilage formation.
Haoqing Yang, Yangyang Cao, Jianpeng Zhang, Yuncun Liang, Xiaomin Su, Chen Zhang, Huina Liu, Xiao Han, Lihua Ge, Zhipeng Fan   +9 more
doaj   +1 more source

A pilot study on biological characteristics of human CD24(+) stem cells from the apical papilla

Journal of Dental Sciences, 2022
Background/purpose: CD24 is a specific cell surface marker for undifferentiated dental stem cells from apical papilla (SCAPs) seen only during root development, before the tooth emerges through gum.
Jing Liang, Ya-Jin Zhao, Jun-Qing Li, Lan Lan, Wen-Jing Tao, Jia-Yuan Wu   +5 more
doaj   +1 more source

MLL1 inhibits the neurogenic potential of SCAPs by interacting with WDR5 and repressing HES1

International Journal of Oral Science, 2023
Mesenchymal stem cell (MSC)-based therapy has emerged as a promising treatment for spinal cord injury (SCI), but improving the neurogenic potential of MSCs remains a challenge.
Chen Zhang, Weilong Ye, Mengyao Zhao, Lujue Long, Dengsheng Xia, Zhipeng Fan   +5 more
doaj   +1 more source

Noncanonical Wnt5a Signaling Suppresses Hippo/TAZ-Mediated Osteogenesis Partly Through the Canonical Wnt Pathway in SCAPs

Drug Design, Development and Therapy, 2022
Yajing Fu,1 Dan Ma,2 Fengyan Fan,3 Tongke Sun,1 Ruiqi Han,1 Yanran Yang,1 Jun Zhang1 1Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration ...
Fu Y, Ma D, Fan F, Sun T, Han R, Yang Y, Zhang J   +6 more
doaj