Results 61 to 70 of about 125 (95)

To Assess the Cell Viability of Triple Antibiotic Paste under Confocal Microscope: An In Vitro Study [PDF]

Journal of South Asian Association of Pediatric Dentistry
Background and aim: Regenerative endodontic procedures (REPs) rely on the viability of stem cells from the apical papilla (SCAPs) to promote tissue repair and regeneration in immature teeth.
Elanthendral Saravanan, Mahesh Ramakrishnan   +1 more
doaj   +1 more source

Exosomes derived from apical papilla stem cells improve NASH by regulating fatty acid metabolism and reducing inflammation

Molecular Medicine
Background Apical papilla stem cells (SCAPs) exhibit significant potential for tissue repair, characterized by their anti-inflammatory and pro-angiogenic properties.
Yifei Nie, Wenqing Meng, Duanqin Liu, Ziqing Yang, Wenhao Wang, Huiping Ren, Kai Mao, Weipeng Lan, Chuanhua Li, Zhifeng Wang, Jing Lan   +10 more
doaj   +1 more source

Sustained Mg/Sr ion delivery from injectable silk fibroin hydrogels drives SCAP osteogenic differentiation

iScience
Summary: This study highlights the biomedical relevance of injectable TS (tannic acid-silk fibroin)-Mg/Sr hydrogels in alveolar bone repair, particularly their prospective role as carriers for stem cells from the apical papilla (SCAPs) in tissue ...
Chen Chen, Zhengrong Gao, Yuman Li, Tuanfeng Zhou, Huimin Zheng, Shengjie Jiang, Yue Yang, Yan Wei   +7 more
doaj   +1 more source

Inhibition of miR-615-3p enhances dentinogenesis in scaps via PVT1-mediated mitochondrial regulation

Stem Cell Research & Therapy
Background Mesenchymal stem cells (MSCs) are critical for dental tissue regeneration, yet their differentiation potential is tightly regulated by microRNAs (miRNAs).
Haoqing Yang, Yishu Huang, Jiaxin Song, Xiao Han, Fengning Yuan, Zhipeng Fan   +5 more
doaj   +1 more source

Lumican from DESC spheroids enhances odontoblastic differentiation of SCAPs

Stem Cell Research & Therapy
Aim During the tooth-root elongation phase, dental epithelial stem cells (DESCs) cluster together and release various signaling molecules, facilitating the differentiation of stem cells from the apical papilla (SCAPs) into odontoblasts.
Qinyao Zhang, Shuwei Huang, Xiaoqian Liu, Meijiu Zhang, Jun Sun, Mingzhu Liu, Hemin Nie, Lei Lei   +7 more
doaj   +1 more source

A Biomimetic Approach to Diode Laser Use in Endodontic Treatment of Immature Teeth: Thermal, Structural, and Biological Analysis

Biomimetics
The root walls of immature permanent teeth are often weak, thin, and short, making regenerative endodontic treatment (RET) necessary. The goal of RET is to create a favorable environment for further root development.
Dijana D. Mitic, Maja S. Milosevic Markovic, Igor D. Jovanovic, Dragan D. Mancic, Kaan Orhan, Vukoman R. Jokanovic, Dejan Lj. Markovic   +6 more
doaj   +1 more source

Roles of basic fibroblast growth factor, stem cells from dental pulp and apical papilla in the repair and regeneration of dental pulp and other tissues/organs

Journal of Dental Sciences
Currently, the concept of regeneration and regenerative therapies are already being applied clinically to treat pulpal and periodontal diseases, as well as to repair and regenerate systemic organs and tissues.
Pin-Hsuan Wu, Yan-Hsiung Wang, Ying-Chu Lin, Ya-Shuan Chou, Mei-Chi Chang, Jiiang-Huei Jeng   +5 more
doaj   +1 more source

Prolonged high-density culture with restricted medium renewal induces epithelial-like plasticity in apical papilla stem cells

Biomolecules & Biomedicine
Stem cells from the apical papilla (SCAPs) are dental mesenchymal stem cells known for their high proliferative and multilineage potential. However, prolonged in vitro expansion may alter their phenotype due to microenvironmental stress.
Kameliya Kercheva, Marina Miteva, Silvia Kalenderova, Vanyo Mitev, Zornitsa Mihaylova, Nikolay Ishkitiev, Violeta S. Dimitrova   +6 more
doaj   +1 more source

Protein Arginine Methyltransferase 6 Regulated Odontogenic Differentiation and Mitochondrial Function of Stem Cells from Apical Papilla Through its Nuclear Localization Sequence via β-catenin Pathway

International Dental Journal
Objectives: Odontogenic differentiation of stem cells from apical papilla (SCAPs) is critical for pulp regeneration therapy. Protein arginine methyltransferase 6 (PRMT6) plays an important role in stem cell differentiation, but the specific functions and
Wanhao Yan, Xiaoli Guo, Bingqi Zhao, Yongkang Li, Zhe Shen, Ruitang Shi, Chen Zhang   +6 more
doaj   +1 more source

Stem cell-based tissue engineering for the regeneration of periodontal structures: A systemic review of current progress and barriers

Medicine Science
Periodontal disease (PD) is characterized by gum inflammation, ranging from reversible gingivitis to irreversible periodontitis. Periodontitis compromises the foundation of oral health by degrading periodontal tissues that support teeth, namely the ...
Anahita Ghafarian, Sathees B Chandra
doaj   +1 more source