Results 11 to 20 of about 2,493,460 (390)

Identification of a residue in hepatitis C virus E2 glycoprotein that determines scavenger receptor BI and CD81 receptor dependency and sensitivity to neutralizing antibodies. [PDF]

, 2008
Hepatitis C virus (HCV) infection is dependent on at least three coreceptors: CD81, scavenger receptor BI (SR-BI), and claudin-1. The mechanism of how these molecules coordinate HCV entry is unknown.
Balfe, Peter, Bassendine, Margaret F, Drummer, Heidi E, Grove, Joe, McKeating, Jane A, Nielsen, Søren, Zhong, Jin   +6 more
core   +5 more sources

Scavenger Receptor Structure and Function in Health and Disease [PDF]

Cells, 2015
Scavenger receptors (SRs) are a ‘superfamily’ of membrane-bound receptors that were initially thought to bind and internalize modified low-density lipoprotein (LDL), though it is currently known to bind to a variety of ligands including endogenous ...
Izma Abdul Zani, S. L. Stephen, Nadeem A. Mughal, David Russell, S. Homer-Vanniasinkam, S. Wheatcroft, S. Ponnambalam   +6 more
semanticscholar   +2 more sources

Erratum for Velasco-de Andrés et al., "The Lymphocytic Scavenger Receptor CD5 Shows Therapeutic Potential in Mouse Models of Fungal Infection". [PDF]

Antimicrob Agents Chemother, 2023
Velasco-de Andrés M, Català C, Casadó-Llombart S, Martínez-Florensa M, Simões I, García-Luna J, Mourglia-Ettlin G, Zaragoza Ó, Carreras E, Lozano F.   +9 more
europepmc   +3 more sources

Scavenger Receptor C1 Mediates Toxicity of Binary Toxin from Lysinibacillus sphaericus to Ag55 Cells [PDF]

Toxins
Lysinibacillus sphaericus harboring Binary (BinA and BinB) toxins is highly toxic against Anopheles and Culex mosquito larvae. The Anopheles Ag55 cell line is a suitable model for investigating the mode of Bin toxin action.
Qi Zhang, Gang Hua, Laramie Smith, Michael J. Adang   +3 more
doaj   +2 more sources

Class B scavenger receptor resists WSSV replication by recognizing the viral lipid molecule and promoting phagocytosis [PDF]

Journal of Virology
Class B scavenger receptors (SRBs) have been well-studied in bacteria-induced immune responses in invertebrates. However, the status of SRB-defending viruses remains unclear.
Yi-Heng Huang, Xin-Lu Guo, Meng-Ke Shan, Gui-Wen Yang, Hui-Ting Yang   +4 more
doaj   +2 more sources

Scavenger receptors [PDF]

Current Biology, 2020
Scavenger receptors (SRs) are a large family of cell-surface receptors that are diverse in their structure and biological function and are divided into different classes. SRs can bind to a range of ligands and enhance the elimination of altered-self or non-self targets.
Ali, Alquraini, Joseph, El Khoury
openaire   +2 more sources

The role of macrophage scavenger receptor 1 (MSR1) in inflammatory disorders and cancer

Frontiers in Immunology, 2022
Macrophage scavenger receptor 1 (MSR1), also named CD204, holds key inflammatory roles in multiple pathophysiologic processes. Present primarily on the surface of various types of macrophage, this receptor variably affects processes such as ...
Jack Gudgeon, J. L. Marín-Rubio, M. Trost   +2 more
semanticscholar   +1 more source

Extensive diet-induced atherosclerosis in scavenger receptor class B type 1-deficient mice is associated with substantial leukocytosis and elevated vascular cell adhesion molecule-1 expression in coronary artery endothelium

Frontiers in Physiology, 2023
High levels of low density lipoprotein (LDL) cholesterol and low levels of high density lipoprotein (HDL) cholesterol are risk factors for cardiovascular disease. Mice that lack genes involved in the clearance of LDL from the bloodstream, such as the LDL
Mark T. Fuller, Mark T. Fuller, Omid Dadoo, Omid Dadoo, Ting Xiong, Ting Xiong, Pardh Chivukula, Pardh Chivukula, Melissa E. MacDonald, Samuel K. Lee, Samuel K. Lee, Richard C. Austin, Richard C. Austin, Suleiman A. Igdoura, Bernardo L. Trigatti, Bernardo L. Trigatti   +15 more
doaj   +1 more source

Scavenger receptor-A is a biomarker and effector of rheumatoid arthritis: A large-scale multicenter study

Nature Communications, 2020
Early diagnosis is critical to improve outcomes in rheumatoid arthritis (RA), but current diagnostic tools have limited sensitivity. Here we report a large-scale multicenter study involving training and validation cohorts of 3,262 participants.
F. Hu, Xiang Jiang, Chunqing Guo, Yingni Li, Shixian Chen, Wei Zhang, Yan Du, Ping Wang, Xi Zheng, X. Fang, Xin Li, Jing Song, Yang-yang Xie, F. Huang, J. Xue, M. Bai, Yuan Jia, Xu Liu, L. Ren, Xiaoying Zhang, Jianping Guo, Hu-dan Pan, Yin Su, H. Yi, H. Ye, Daming Zuo, Juan Li, Huaxiang Wu, Yongfu Wang, Ru Li, Liang Liu, Xiang-Yang Wang, Zhanguo Li   +32 more
semanticscholar   +1 more source

Targeting a scavenger receptor on tumor-associated macrophages activates tumor cell killing by natural killer cells

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance Here we report that targeting the pattern recognition receptor MARCO on macrophages within the tumor alters their polarization and in turn activate natural killer (NK) cells to kill the tumor.
S. Eisinger, D. Sarhan, Vanessa F. Boura, Itziar Ibarlucea-Benitez, Sofia Tyystjärvi, G. Oliynyk, Marie Arsenian-Henriksson, D. Lane, Stina L Wikström, R. Kiessling, T. Virgilio, S. F. Gonzalez, D. Kaczynska, Shigeaki Kanatani, E. Daskalaki, C. Wheelock, S. Sedimbi, B. Chambers, J. Ravetch, M. Karlsson   +19 more
semanticscholar   +1 more source