Results 201 to 210 of about 2,493,460 (390)

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

open access: yesAdvanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li   +17 more
wiley   +1 more source

Role of scavenger receptors as damage-associated molecular pattern receptors in Toll-like receptor activation

open access: yesInternational Immunology, 2017
Kyoko Komai   +5 more
semanticscholar   +1 more source

Scavenger Chemokine (CXC Motif) Receptor 7 (CXCR7) Is a Direct Target Gene of HIC1 (Hypermethylated in Cancer 1) [PDF]

open access: hybrid, 2009
Capucine Van Rechem   +11 more
openalex   +1 more source

Platelet Rubicon Bidirectional Regulation of GPVI and Integrin αIIbβ3 Signaling Mitigates Stroke Infarction Without Compromising Hemostasis

open access: yesAdvanced Science, EarlyView.
This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen   +11 more
wiley   +1 more source

Mannose-Binding Lectin Augments the Uptake of Lipid A, Staphylococcus aureus , and Escherichia coli by Kupffer Cells through Increased Cell Surface Expression of Scavenger Receptor A [PDF]

open access: bronze, 2006
Kei Ono   +10 more
openalex   +1 more source

Dengue Virus NS1 Uses Scavenger Receptor B1 as a Cell Receptor in Cultured Cells

open access: green, 2022
Ana C. Alcalá   +5 more
openalex   +2 more sources

Gallium‐Doped MXene Nanozymes Protect Liver Through Multi‐Death Pathway Blockade and Hepatocyte Regeneration

open access: yesAdvanced Science, EarlyView.
This study develops gallium‐doped V2C MXene nanozymes (Ga‐V2C) to treat acetaminophen‐induced liver injury through multi‐death pathway blockade and hepatocyte regeneration. Unlike conventional single‐target therapies like N‐acetylcysteine, Ga‐V2C nanozymes enable oxidative stress suppression, apoptosis, and ferroptosis inhibition, and enhanced ...
Xiaopeng Cai   +13 more
wiley   +1 more source

Class A scavenger receptor MARCO negatively regulates Ace expression and aldosterone production. [PDF]

open access: yesElife
O'Brien CJO   +6 more
europepmc   +1 more source

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