Results 211 to 220 of about 3,306 (240)
Some of the next articles are maybe not open access.
Collagenous macrophage scavenger receptors
Current Opinion in Lipidology, 1996Collagen, the most abundant protein in the human body, is a major constituent of extracellular matrix. Among macrophage membrane proteins, type I and II scavenger receptors and MARCO contain a collagenous domain. Analysis of type I and II receptor knockout mice and histochemical studies indicate that these proteins play roles in scavenger, adhesion and
Tatsuhiko Kodama +5 more
openaire +2 more sources
Macrophage scavenger receptors and atherosclerosis
Trends in Cardiovascular Medicine, 1992The fatty streak is the earliest visible atherosclerotic lesion. Microscopically, this lesion consists of a subendothelial collection of macrophage foam cells that are characterized by their content of numerous lipid droplets. Investigations into the mechanisms responsible for foam cell formation have led to the identification of macrophage scavenger ...
Karen S. Moulton +2 more
openaire +3 more sources
Current Opinion in Lipidology, 2004
This review will survey recent findings on the cholesterol transport and scavenger functions of scavenger receptor BI. Although scavenger receptor BI and CD36 bind many of the same ligands, these two receptors have very specific lipid transport functions: CD36 facilitates the uptake of long chain fatty acids and SR-BI mediates the transport of ...
Margery A. Connelly, David L. Williams
openaire +3 more sources
This review will survey recent findings on the cholesterol transport and scavenger functions of scavenger receptor BI. Although scavenger receptor BI and CD36 bind many of the same ligands, these two receptors have very specific lipid transport functions: CD36 facilitates the uptake of long chain fatty acids and SR-BI mediates the transport of ...
Margery A. Connelly, David L. Williams
openaire +3 more sources
Scavenger-Receptor Targeted Photodynamic Therapy¶
Photochemistry and Photobiology, 2000Covalent conjugation of a photosensitizer to a ligand that specifically recognized and internalized by a cell-surface receptor may be a way of improving the selectivity of photodynamic therapy (PDT). The class A Type-I scavenger receptor of macrophages, which among other ligands recognizes maleylated serum albumin and has a high capacity is a good ...
Jaimie L. Miller +2 more
openaire +3 more sources
Scavenger receptors: Implications in atherothrombotic disorders
The International Journal of Biochemistry & Cell Biology, 2011Scavenger receptors are modified lipoprotein binding receptors, expressed on the surface of a variety of cells including endothelial, macrophages and platelets. The most extensively studied class B scavenger receptors comprise of CD36 and SR-BI and have been found to bind to native and modified LDL.
Mohammad Z. Ashraf, Neha Gupta
openaire +3 more sources
Scavenger receptors in innate immunity
Current Opinion in Immunology, 1996Scavenger receptors are cell-surface proteins expressed by mammalian monocytes and macrophages and by invertebrate hemocytes, among other cell types. They exhibit distinctive ligand-binding properties, recognizing a wide range of ligands that include microbial surface constituents and intact microbes.
openaire +3 more sources
Scavenger receptor Bl and cholesterol trafficking
Current Opinion in Lipidology, 1999Scavenger receptor BI (SR-BI) mediates the selective uptake of HDL cholesteryl ester into steroidogenic cells and the liver and is a major determinant of the plasma HDL concentration in the mouse. Recent studies indicate that SR-BI also alters the metabolism of apolipoprotein B-containing particles and influences the development of atherosclerosis in ...
Snehasikta Swarnakar +6 more
openaire +2 more sources
Scavenger Receptors, Oxidized LDL, and Atherosclerosis
Annals of the New York Academy of Sciences, 2001Abstract: Oxidized LDL (OxLDL) competes with oxidatively damaged and apoptotic cells for binding to mouse peritoneal macrophages, implying the presence of one or more common domains. However, the nature of the ligands involved has not been determined.
Joseph L. Witztum +12 more
openaire +3 more sources
New scavenger receptors and their functions in atherogenesis
Current Atherosclerosis Reports, 2002LOX-1 may play important roles in oxLDL-induced apoptosis of intimal VSMC. Although multiple molecules may be involved in oxLDL uptake in macrophages, SR-PSOX might contribute to oxLDL-induced accumulation of cholesteryl ester in macrophages. These biologic functions of LOX-1 and SR-PSOX may stimulate atherosclerotic plaque rupture. Future studies with
Toru Kita, Noriaki Kume
openaire +3 more sources
Scavenging for receptors [PDF]
Nature, 1990 Joseph L. Goldstein, Michael S. Brown
openaire +1 more source