Results 251 to 260 of about 2,442,074 (290)

Scavenger receptors: Implications in atherothrombotic disorders

The International Journal of Biochemistry & Cell Biology, 2011
Scavenger receptors are modified lipoprotein binding receptors, expressed on the surface of a variety of cells including endothelial, macrophages and platelets. The most extensively studied class B scavenger receptors comprise of CD36 and SR-BI and have been found to bind to native and modified LDL.
Mohammad Z. Ashraf, Neha Gupta
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Scavenger receptors in innate immunity

Current Opinion in Immunology, 1996
Scavenger receptors are cell-surface proteins expressed by mammalian monocytes and macrophages and by invertebrate hemocytes, among other cell types. They exhibit distinctive ligand-binding properties, recognizing a wide range of ligands that include microbial surface constituents and intact microbes.
openaire   +3 more sources

Scavenger receptor Bl and cholesterol trafficking

Current Opinion in Lipidology, 1999
Scavenger receptor BI (SR-BI) mediates the selective uptake of HDL cholesteryl ester into steroidogenic cells and the liver and is a major determinant of the plasma HDL concentration in the mouse. Recent studies indicate that SR-BI also alters the metabolism of apolipoprotein B-containing particles and influences the development of atherosclerosis in ...
Snehasikta Swarnakar, David L. Williams, Ryan E. Temel, George H. Rothblat, Margery A. Connelly, Michael C. Phillips, de la Llera-Moya M   +6 more
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Scavenger Receptors, Oxidized LDL, and Atherosclerosis

Annals of the New York Academy of Sciences, 2001
Abstract: Oxidized LDL (OxLDL) competes with oxidatively damaged and apoptotic cells for binding to mouse peritoneal macrophages, implying the presence of one or more common domains. However, the nature of the ligands involved has not been determined.
Joseph L. Witztum, Oswald Quehenberger, Peter X. Shaw, Wulf Palinski, David A. Bird, Agnès Boullier, Mi-Kyung Chang, Daniel Steinberg, Kristin Gillotte-Taylor, Sohvi Hörkkö, Valeska Terpstra, Edward A. Dennis, Peter Friedman   +12 more
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Direct recognition of superparamagnetic nanocrystals by macrophage scavenger receptor SR-AI.

ACS Nano, 2013
Scavenger receptors (SRs) are molecular pattern recognition receptors that have been shown to mediate opsonin-independent uptake of therapeutic and imaging nanoparticles, underlying the importance of SRs in nanomedicine.
Ying S. Chao, P. Karmali, Rajesh Mukthavaram, S. Kesari, V. Kouznetsova, I. Tsigelny, D. Simberg   +6 more
semanticscholar   +1 more source

Scavenging for receptors [PDF]

Nature, 1990
Joseph L. Goldstein, Michael S. Brown
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New scavenger receptors and their functions in atherogenesis

Current Atherosclerosis Reports, 2002
LOX-1 may play important roles in oxLDL-induced apoptosis of intimal VSMC. Although multiple molecules may be involved in oxLDL uptake in macrophages, SR-PSOX might contribute to oxLDL-induced accumulation of cholesteryl ester in macrophages. These biologic functions of LOX-1 and SR-PSOX may stimulate atherosclerotic plaque rupture. Future studies with
Toru Kita, Noriaki Kume
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Class A scavenger receptors, macrophages, and atherosclerosis

Current Opinion in Lipidology, 2001
The scope of this review is to discuss the new advances in our understanding of the role of scavenger receptor class A in the initiation and modulation of the atherosclerotic process. Through the approaches of gene manipulation in the mouse model, a substantial body of literature has accumulated that depicts scavenger receptor class A as a central ...
Sergio Fazio, MacRae F. Linton
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Characterization of the Hepatic Scavenger Receptor

1987
The hepatic scavenger receptor is a high affinity receptor on the surface of the sinusoidal endothelial cells and Kupffer cells (Nagelkerke et al., 1983; Pitas et al., 1985). it was suggested that the hepatic scavenger receptor could remove modified forms of LDL from the circulating blood and protect the arterial wall from an increased influx of ...
H Sinn, G. Schettler, H. A. Dresel, D. P. Via, E. Friedrich   +4 more
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Scavenger receptors for oxidized and glycated proteins

Amino Acids, 2003
Our present knowledge on chemically modified proteins and their receptor systems is originated from a proposal by Goldstein and Brown in 1979 for the receptor for acetylated LDL which is involved in foam cell formation, one of critical steps in atherogenesis.
Seikoh Horiuchi, Y. Sakamoto, M. Sakai
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