Results 271 to 280 of about 1,335,649 (315)

Hemoglobin scavenger receptor CD163 as a potential biomarker of hemolysis-induced hepatobiliary injury in sickle cell disease.

Am J Physiol Cell Physiol
Kaminski TW, Sivanantham A, Mozhenkova A, Smith A, Ungalara R, Dubey RK, Shrestha B, Hanway C, Katoch O, Tejero J, Sundd P, Novelli EM, Kato GJ, Pradhan-Sundd T.   +13 more
europepmc   +1 more source

Macrophage Scavenger Receptor(s) and Oxidatively Modified Proteins in Endometriosis

Fertility and Sterility, 1998
ObjectiveTo determine whether cultured human peritoneal macrophages have functional scavenger receptor(s) and whether activation of macrophages in endometriosis may involve an increase in scavenger receptor activity.DesignA controlled clinical study ...
Sampath Parthasarathy, Wulf Palinski, Ana A Murphy   +2 more
exaly   +2 more sources

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Endothelial scavenger receptors

Progress in Lipid Research, 2006
In the past few decades, cDNAs for endothelial scavenger receptors that bind to negatively charged molecules, particularly acetylated low density lipoproteins (Ac-LDL), have been cloned by expression cloning using modified LDL as ligands. A prototypic members of endothelial scavenger receptor family, namely, scavenger receptor class B type I (SR-BI ...
Hideki, Adachi, Masafumi, Tsujimoto
openaire   +2 more sources

Regulation of Scavenger Receptor Expression in Smooth Muscle Cells by Protein Kinase C

Arteriosclerosis, Thrombosis, and Vascular Biology, 1997
Phorbol esters increase scavenger-receptor mRNA expression and receptor activity in smooth muscle cells (SMCs). Our present results demonstrate that activation of protein kinase C (PKC) mediates this increase in receptor expression.
Michele Mietus-Snyder, Robert E Pitas, C K Glass   +2 more
exaly   +2 more sources

Hemoglobin and Heme Scavenger Receptors

Antioxidants & Redox Signaling, 2010
Heme, the functional group of hemoglobin, myoglobin, and other hemoproteins, is a highly toxic substance when it appears in the extracellular milieu. To circumvent potential harmful effects of heme from hemoproteins released during physiological or pathological cell damage (such as hemolysis and rhabdomyolysis), specific high capacity scavenging ...
Nielsen MJ, Møller HJ, Moestrup SK.
openaire   +3 more sources

Macrophage scavenger receptors

Current Opinion in Lipidology, 1994
Macrophage scavenger receptors are integral membrane proteins whose ability to bind and degrade modified LDL has implicated them in the process of atherosclerotic foam cell formation. Their ability to bind non-lipoprotein ligands suggests that they participate in other macrophage-associated host defense activities.
openaire   +2 more sources

Identification of the haemoglobin scavenger receptor

Nature, 2001
Intravascular haemolysis is a physiological phenomenon as well as a severe pathological complication when accelerated in various autoimmune, infectious (such as malaria) and inherited (such as sickle cell disease) disorders. Haemoglobin released into plasma is captured by the acute phase protein haptoglobin, which is depleted from plasma during ...
Madsen, Mette; id_orcid 0000-0001-7241-6505, Graversen, J. H., Jacobsen, Christian, Sonne, Ole, Hoffmann, H.-J., Law, S. K. A., Moestrup, Søren Kragh   +6 more
openaire   +3 more sources

Macrophage scavenger receptors and atherosclerosis

Trends in Cardiovascular Medicine, 1992
The fatty streak is the earliest visible atherosclerotic lesion. Microscopically, this lesion consists of a subendothelial collection of macrophage foam cells that are characterized by their content of numerous lipid droplets. Investigations into the mechanisms responsible for foam cell formation have led to the identification of macrophage scavenger ...
H, Wu, K S, Moulton, C K, Glass
openaire   +2 more sources

Scavenger receptor regulation and atherosclerosis

BioFactors, 2000
AbstractAtherosclerosis and its complications, such as coronary heart disease, heart infarction and stroke, are the leading causes of death in the developed world. High blood pressure, diabetes, smoking and a diet high in cholesterol and lipids clearly increase the likelihood of premature atherosclerosis, albeit other factors, such as the individual ...
ZINGG JM, RICCIARELLI, ROBERTA, AZZI A.
openaire   +4 more sources

Collagenous macrophage scavenger receptors

Current Opinion in Lipidology, 1996
Collagen, the most abundant protein in the human body, is a major constituent of extracellular matrix. Among macrophage membrane proteins, type I and II scavenger receptors and MARCO contain a collagenous domain. Analysis of type I and II receptor knockout mice and histochemical studies indicate that these proteins play roles in scavenger, adhesion and
T, Kodama, T, Doi, H, Suzuki, K, Takahashi, Y, Wada, S, Gordon   +5 more
openaire   +2 more sources