Results 21 to 30 of about 2,493,460 (390)

Interactions of ferritin with scavenger receptor class A members

Journal of Biological Chemistry, 2020
Scavenger receptors are a superfamily of membrane-bound receptors that recognize both self and nonself targets. Scavenger receptor class A (SR-A) has five known members (SCARA1 to -5 or SR-A1 to -A5), which are type II transmembrane proteins that form ...
Bowen Yu, Chen Cheng, Yichun Wu, Luqiang Guo, Dandan Kong, Ze Zhang, Yuanyuan Wang, Enlin Zheng, Yingbin Liu, Yongning He   +9 more
semanticscholar   +1 more source

The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides

Nature Communications, 2020
Endogenous opioid peptides and prescription opioid drugs modulate pain, anxiety and stress by activating opioid receptors, currently classified into four subtypes. Here we demonstrate that ACKR3/CXCR7, hitherto known as an atypical scavenger receptor for
M. Meyrath, M. Szpakowska, J. Zeiner, L. Massotte, Myriam P Merz, Tobias Benkel, Katharina Simon, Jochen Ohnmacht, J. D. Turner, R. Krüger, V. Seutin, M. Ollert, E. Kostenis, A. Chevigné   +13 more
semanticscholar   +1 more source

Macrophage-derived upd3 Cytokine causes impaired glucose homeostasis and reduced lifespan in drosophila fed a lipid-rich diet [PDF]

, 2014
Long-term consumption of fatty foods is associated with obesity, macrophage activation and inflammation, metabolic imbalance, and a reduced lifespan. We took advantage of Drosophila genetics to investigate the role of macrophages and the pathway(s) that ...
Dionne, MS, Geissmann, F, Kierdorf, K, Pouchelon, CA, Vivancos, V, Woodcock, KJ   +5 more
core   +1 more source

Lewis X antigen mediates adhesion of human breast carcinoma cells to activated endothelium. Possible involvement of the endothelial scavenger receptor C-Type lectin [PDF]

, 2007
Lewis x (Lex, CD15), also known as SSEA-1 (stage specific embryonic antigen-1), is a trisaccharide with the structure Galβ(1–4)Fucα(1–3)GlcNAc, which is expressed on glycoconjugates in human polymorphonuclear granulocytes and various tumors such as colon
A Hittelet, AM Roon van, C Ballaré, D Vestweber, DS Johnston, E Spooncer, EA Jaffé, ED Ball, EG Rizzatti, F Sánchez-Madrid, HC Gooi, HD Soule, IHN Wong, J Kitayama, J Mitoma, J Mordoh, J Mordoh, J-W Liao, JF Harris, JI Yamashita, JL Magnani, José Mordoh, JP Buyon, K Drbal, KL Allendoerfer, KM Skubitz, KM Skubitz, KP Gisbergen van, Kurt Drickamer, L Lucka, M Albrechtsen, M Capurro, M Capurro, M-L Majuri, Mariana Isabel Capurro, María Marcela Barrio, María Teresa Elola, Maureen E. Taylor, MK Robinson, ML Phillips, MM Burdick, N Kawamura, O Ohana-Malka, Peter J. Coombs, PJ Coombs, R Giavazzi, R Kannagi, S D´Costa, S Hakomori, SC Stocks, T Bild, TB Geijtenbeek   +51 more
core   +1 more source

Lack of a direct role for macrosialin in oxidized LDL metabolism

Journal of Lipid Research, 2003
Murine macrosialin (MS), a scavenger receptor family member, is a heavily glycosylated transmembrane protein expressed predominantly in macrophage late endosomes. MS is also found on the cell surface where it is suggested, on the basis of ligand blotting,
Maria C. de Beer, Zhenze Zhao, Nancy R. Webb, Deneys R. van der Westhuyzen, Willem J.S. de Villiers   +4 more
doaj   +1 more source

Amino terminus of apolipoprotein B suffices to produce recognition of malondialdehyde-modified low density lipoprotein by the scavenger receptor of human monocyte-macrophages

Journal of Lipid Research, 1997
Malondialdehyde, a product of lipid peroxidation, produces threshold conversion of low density lipoprotein (LDL) to a form recognized by type I and type II scavenger receptors of monocyte-macrophages.
J Kreuzer, A L White, T J Knott, M L Jien, M Mehrabian, J Scott, S G Young, M E Haberland   +7 more
doaj   +1 more source

Indolinyl-Thiazole Based Inhibitors of Scavenger Receptor-BI (SR-BI)-Mediated Lipid Transport [PDF]

, 2014
A potent class of indolinyl-thiazole based inhibitors of cellular lipid uptake mediated by scavenger receptor, class B, type I (SR-BI) was identified via a high-throughput screen of the National Institutes of Health Molecular Libraries Small Molecule ...
Bennion, Melissa, Dandapani, Sivaraman, Dockendorff, Chris, Faloon, Patrick W., Krieger, Monty, Lam, Garrett, Lewis, Timothy A., Munoz, Benito, Nag, Partha P., Negri, Joseph, Nieland, Thomas J.F., Palmer, Michelle A., Paterson, Conor, Penman, Marsha, Perez, José R., Pu, Jun, Schreiber, Stuart L., Youngsaye, Willmen, Yu, Miao   +18 more
core   +3 more sources

Factors regulating the activities of the low density lipoprotein receptor and the scavenger receptor on human monocyte-macrophages.

Journal of Lipid Research, 1981
Improved techniques of cell isolation resulted in 90 to 100 million monocytes from a single donor. Addition of low density lipoprotein (LDL) to to cultures of these cells resulted in the down regulation of LDL receptor activity.
A M Fogelman, M E Haberland, J Seager, M Hokom, P A Edwards   +4 more
doaj   +1 more source

Insights into the ligand binding specificity of SREC‐II (scavenger receptor expressed by endothelial cells)

FEBS Open Bio, 2021
SREC‐II (scavenger receptor expressed by endothelial cells II) is a membrane protein encoded by the SCARF2 gene, with high homology to class F scavenger receptor SR‐F1, but no known scavenging function.
Catherine Wicker‐Planquart, Pascale Tacnet‐Delorme, Laurence Preisser, Samy Dufour, Yves Delneste, Dominique Housset, Philippe Frachet, Nicole M Thielens   +7 more
doaj   +1 more source

Evolution of Fc Receptor-Like Scavenger in Mammals

Frontiers in Immunology, 2021
Fc receptor-like (FCRL) molecules comprise a large family of receptors, homologous to the receptors for the Fc portion of immunoglobulins (FCR). Within this family, an unusual gene known to exist in mice, rats and dogs, termed FCRLS, encodes a chimeric ...
Maria Carolina Matos, Maria Carolina Matos, Ana Pinheiro, José Melo-Ferreira, José Melo-Ferreira, Randall S. Davis, Pedro José Esteves, Pedro José Esteves, Pedro José Esteves   +8 more
doaj   +1 more source