Results 61 to 70 of about 2,493,460 (390)
Scavenger Receptors in Atherosclerosis [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2006 Atherosclerotic vascular disease arises as a consequence of the deposition and retention of serum lipoproteins in the artery wall. Macrophages in lesions have been shown to express ≥6 structurally different scavenger receptors for uptake of modified forms of low-density lipoproteins (LDLs) that promote the cellular accumulation of cholesterol.
Kathryn J, Moore, Mason W, Freeman
openaire +2 more sources
Scavenger receptor class B type I as a receptor for oxidized low density lipoprotein
Journal of Lipid Research, 2001 Scavenger receptor class B type I (SR-BI) has been established as the primary mediator of the selective transfer of lipids from HDL to mammalian cells.
Kristin Gillotte-Taylor +4 more
doaj +1 more source
PLoS Pathogens, 2016 Scavenger receptors are an important class of pattern recognition receptors that play several important roles in host defense against pathogens. The class C scavenger receptors (SRCs) have only been identified in a few invertebrates, and their role in ...
Ming-Chong Yang +7 more
semanticscholar +1 more source
Lipoprotein receptor interactions are not required for monocyte oxidation of LDL.
Journal of Lipid Research, 1995 Upon activation, human peripheral blood monocytes and U937 cells oxidized low density lipoprotein (LDL), converting it to a cytotoxin. The oxidized LDL loses its ability to interact specifically with the native LDL (apoB/E) receptor and becomes a ligand ...
M K Cathcart, Q Li, G M Chisolm, 3rd
doaj +1 more source
The effects of exogenous lipid on THP-1 cells : an in vitro model of airway aspiration? [PDF]
, 2017 Chronic inflammatory diseases of the airways are associated with gastro-oesophageal reflux (GOR) and aspiration events. The observation of lipid laden macrophages (LLM) within the airway may indicate aspiration secondary to GOR.
Adams +6 more
core +2 more sources
A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease [PDF]
, 2017 Scavenger receptors constitute a large family of proteins that are structurally diverse and participate in a wide range of biological functions. These receptors are expressed predominantly by myeloid cells and recognize a diverse variety of ligands ...
Acton +46 more
core +1 more source
Scavenger Receptors and Atherosclerosis
Biological Research, 2000 Scavenger receptors were discovered as cell surface proteins capable of binding and internalization of modified lipoproteins. These receptors exhibit a broad ligand binding specificity including potential physiological and pathophysiological ligands other than modified lipoproteins.
openaire +6 more sources
The Integration of Positron Emission Tomography With Magnetic Resonance Imaging [PDF]
, 2008 A number of laboratories and companies are currently exploring the development of integrated imaging systems for magnetic resonance imaging (MRI) and positron emission tomography (PET).
Cherry, Simon R. +2 more
core +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source