Differentiation-dependent expression and localization of the class B type I scavenger receptor in intestine [PDF]
Journal of Lipid Research, 2001 The current study used the human Caco-2 cell line and mouse intestine to explore the topology of expression of the class B type I scavenger receptor (SR-BI) in intestinal cells.
Sheng F. Cai +3 more
doaj +5 more sources
Protein markers of dysfunctional HDL in scavenger receptor class B type I deficient mice. [PDF]
J Transl Med, 2018 Background Scavenger receptor class B type I (SR-BI) plays a key role in high density lipoproteins (HDL) metabolism. SR-BI deficiency in mice results in enhanced susceptibility to atherosclerosis with abnormal large, cholesterol enriched, and functional ...
Cao J, Xu Y, Li F, Shang L, Fan D, Yu H.
europepmc +6 more sources
Scavenger receptor class B type I is a plasma membrane cholesterol sensor. [PDF]
Circ Res, 2013 Rationale: Signal initiation by the high-density lipoprotein (HDL) receptor scavenger receptor class B, type I (SR-BI), which is important to actions of HDL on endothelium and other processes, requires cholesterol efflux and the C-terminal transmembrane domain.
Saddar S +14 more
europepmc +5 more sources
Lp-PLA2, scavenger receptor class B type I gene (SCARB1) rs10846744 variant, and cardiovascular disease. [PDF]
PLoS One, 2018 BACKGROUND:We previously reported association of SCARB1 SNP rs10846744 with common carotid IMT (cIMT) and cardiovascular disease (CVD) events. Since rs10846744 has been reported in association with Lp-PLA2 mass and activity, we hypothesized that ...
Manichaikul A +19 more
europepmc +2 more sources
Farnesoid X receptor induces murine scavenger receptor Class B type I via intron binding. [PDF]
PLoS One, 2012 Farnesoid X receptor (FXR) is a nuclear receptor and a key regulator of liver cholesterol and triglyceride homeostasis. Scavenger receptor class B type I (SR-BI) is critical for reverse cholesterol transport (RCT) by transporting high-density lipoprotein
Li G +7 more
europepmc +2 more sources
Scavenger receptor class B type I affects cholesterol homeostasis by magnifying cholesterol flux between cells and HDL [PDF]
Journal of Lipid Research, 2001 Results from several laboratories clearly indicate that expression of scavenger receptor class B type I (SR-BI) enhances the bidirectional flux of cholesterol between cells and lipoproteins.
Margarita de la Llera-Moya +7 more
doaj +2 more sources
Scavenger Receptor Class B, Type I, a CD36 Related Protein in Macrobrachium nipponense: Characterization, RNA Interference, and Expression Analysis with Different Dietary Lipid Sources. [PDF]
Int J Genomics, 2016 The scavenger receptor class B, type I (SR-BI), is a member of the CD36 superfamily comprising transmembrane proteins involved in mammalian and fish lipid homeostasis regulation.
Ding Z +6 more
europepmc +2 more sources
Role Analysis of the <i>scarb1</i> Gene in the Pigmentation of <i>Neocaridina denticulata sinensis</i>. [PDF]
Animals (Basel)Body color is a key economic trait for Neocaridina denticulata sinensis, an important ornamental shrimp. Scarb1 may be an important mediator of astaxanthin uptake, changing the shrimp’s body color.
Zhang L, Wang G, Li H, Zhao T.
europepmc +2 more sources
HDL modification by secretory phospholipase A2 promotes scavenger receptor class B type I interaction and accelerates HDL catabolism [PDF]
Journal of Lipid Research, 2000 During inflammatory states plasma levels of high density lipoprotein (HDL) cholesterol and apolipoprotein A-I (apoA-I) are reduced. Secretory group IIa phospholipase A2 (sPLA2) is a cytokine-induced acute-phase enzyme associated with HDL. Transgenic mice
Frederick C. de Beer +5 more
doaj +2 more sources
Effects of Extracts from Tiaozhi Granule and Its Components on Expression of Scavenger Receptor Class B Type I. [PDF]
Evid Based Complement Alternat Med, 2016 Yu X +5 more
europepmc +3 more sources