Reverse cholesterol transport (RCT) can proceed through the classic hepatobiliary route or through the nonbiliary transintestinal cholesterol efflux (TICE) pathway.
Kanwardeep S. Bura +16 more
doaj +1 more source
Rare SCARB1 mutations associate with high-density lipoprotein cholesterol but not with coronary artery disease [PDF]
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked FilesAIMS: Scavenger receptor Class B Type 1 (SR-BI) is a major receptor for high ...
Arnadottir, Gudny A +13 more
core +2 more sources
CD36 does not play a direct role in HDL or LDL metabolism
CD36 and scavenger receptor class B, type I (SR-BI) are both class B scavenger receptors that recognize a broad variety of ligands, including oxidized low density lipoprotein (oxLDL), HDL, anionic phospholipids, and apoptotic cells.
Willem J.S. de Villiers +5 more
doaj +1 more source
LDL transcytosis passes through the trans-Golgi network and requires Rab10
Atherosclerosis begins with the subendothelial retention of LDLs from the circulation. While LDL transcytosis across the endothelium is mediated by scavenger receptor class B type I and activin-like kinase receptor 1 and is usually independent of LDL ...
Tse Wing Winnie Ho +2 more
doaj +1 more source
Identification of a Candidate CD5 Homologue in the Amphibian Xenopus laevis [PDF]
We identified a novel T cell Ag in the South African clawed toad (Xenopus laevis) by a mAb designated 2B1. This Ag is present in relatively high levels on most thymocytes, approximately 65% of splenocytes, 55% of PBL, and 65% of intestinal lymphocytes ...
Cooper, Max D. +5 more
core
Differential roles of Scavenger receptor class B type I: A protective molecule and a facilitator of atherosclerosis (Review). [PDF]
Ma B +7 more
europepmc +1 more source
A Chemical Genetic Approach To The Study Of Cellular Transport [PDF]
The focus of this thesis is the use of chemical genetics to study two different aspects of membrane biology, (a) the mechanisms underlying cellular lipid transport and (b) the intersection between endocytic and exocytic traffic.
Nieland, T.J.F.
core +2 more sources
Protein deglycosylation can drastically affect the cellular uptake [PDF]
Ghazaryan, A. +2 more
core +2 more sources
CARDIOPROTECTION BY HIGH DENSITY LIPOPROTEIN IS MEDIATED BY THE SCAVENGER RECEPTOR CLASS B TYPE 1 [PDF]
Cardiovascular disease and cancer are the leading causes of death in Canada and are a major burden to the health of developed societies. Three quarters of all cardiovascular related deaths are due to ischemic heart disease and heart attack. Doxorubicin
Durham, Kristina
core
Nanocarrier-Assisted Delivery of Drug(s) for the Targeted Treatment of Neurodegenerative Disease
Apolipoprotein A-I (apoA-I)-coated nanoemulsion particles target scavenger receptors. Adsorbed apoA-I (from the bloodstream) mediates/facilitates this targeted molecular contact, which is followed by receptor-mediated endocytosis and subsequent ...
Joseph S. D’Arrigo
doaj +1 more source

