Distinct macrophage uptake of engineered and biological particles driven by host age and sex. [PDF]
Toita R, Shimizu Y, Kang JH.
europepmc +1 more source
The preparation for Tunisian pomegranate anthocyanin extract. The molecular mechanisms underlying the antioxidant effects of these compounds were investigated using network pharmacology and molecular docking. Antioxidant activity was evaluated through DPPH, ABTS, and FRAP assays, whereas the effects on oxidative stress and inflammation were examined in
Jing Zhang +6 more
wiley +1 more source
Transcriptomic characterization of mucosal hemocytes in the eastern oyster (<i>Crassostrea virginica</i>) underlines their potential role as immune sentinels. [PDF]
Abdallah S +3 more
europepmc +1 more source
AI‐Driven Cancer Multi‐Omics: A Review From the Data Pipeline Perspective
The exponential growth of cancer multi‐omics data brings opportunities and challenges for precision oncology. This review systematically examines AI's role in addressing these challenges, covering generative models, integration architectures, Explainable AI for clinical trust, clinical applications, and key directions for clinical translation.
Shilong Liu, Shunxiang Li, Kun Qian
wiley +1 more source
Glycopolymer binds pathogenic IgM autoantibodies and pulls them into the mononuclear phagocyte system for degradation. [PDF]
Aliu B +7 more
europepmc +1 more source
OxSpred, an eXtreme‐Gradient‐Boosting‐‐based supervised learning model, accurately annotates oxidative stress in innate immune cells at the single‐cell level, providing interpretable embeddings with significant biological relevance. This innovative tool revolutionizes the understanding of innate immune cell functions during inflammation and enhances ...
Po‐Yuan Chen, Tai‐Ming Ko
wiley +1 more source
LDL oxidation and cerebrovascular aging: mechanisms of endothelial dysfunction, inflammation, and vascular cognitive impairment and dementia. [PDF]
Ihuoma J +11 more
europepmc +1 more source
This study provides an introduction to Bayesian optimisation targeted for experimentalists. It explains core concepts, surrogate modelling, and acquisition strategies, and addresses common real‐world challenges such as noise, constraints, mixed variables, scalability, and automation.
Chuan He +2 more
wiley +1 more source
Differential Regulatory Effects of Cannabinoids and Vitamin E Analogs on Cellular Lipid Homeostasis and Inflammation in Human Macrophages. [PDF]
Li M, Deo S, Daunert S, Zingg JM.
europepmc +1 more source

