Results 41 to 50 of about 49,496 (188)

3582 Scavenger Receptor Expression is Differentially Affected by DNAzyme-Gold Nanoparticle Conjugates

open access: yesJournal of Clinical and Translational Science, 2019
OBJECTIVES/SPECIFIC AIMS: Scavenger receptor (SR) surface proteins are highly conserved motifs and are implicated in the uptake of nanotherapies. Gold nanoparticles functionalized with DNAzymes (DzNP) represent a promising novel nanotherapy for lung ...
Cory Sylber   +4 more
doaj   +1 more source

Does native Trypanosoma cruzi calreticulin mediate growth inhibition of a mammary tumor during infection? [PDF]

open access: yes, 2016
Indexación: Web of Science.Background: For several decades now an antagonism between Trypanosoma cruzi infection and tumor development has been detected. The molecular basis of this phenomenon remained basically unknown until our proposal that T.
A Colombo   +42 more
core   +1 more source

LRP: a multifunctional scavenger and signaling receptor [PDF]

open access: yesJournal of Clinical Investigation, 2001
The LDL receptor–related protein (LRP) is larger than but structurally similar to other members of the LDL receptor gene family, an ancient family of endocytic receptors (1–3). Whereas the LDL receptor, the founding member of this family, appears to act solely in lipoprotein metabolism, the LRP and other members of this family appear to have other ...
Joachim Herz, Dudley K. Strickland
openaire   +2 more sources

The macrophage scavenger receptor CD163

open access: yesImmunobiology, 2005
Mature tissue macrophages form a first line of defense to recognize and eliminate potential pathogens; these specialized cells are capable of phagocytosis, degradation of self and foreign materials, establishment of cell-cell interactions, and the production of inflammatory mediators.
Fabriek, Babs O   +2 more
openaire   +4 more sources

HSL-knockout mouse testis exhibits class B scavenger receptor upregulation and disrupted lipid raft microdomains[S]

open access: yesJournal of Lipid Research, 2012
There is a tight relationship between fertility and changes in cholesterol metabolism during spermatogenesis. In the testis, class B scavenger receptors (SR-B) SR-BI, SR-BII, and LIMP II mediate the selective uptake of cholesterol esters from HDL, which ...
María Emilia Casado   +8 more
doaj   +1 more source

Hepatoma cell density promotes claudin-1 and scavenger receptor BI expression and hepatitis C virus internalization. [PDF]

open access: yes, 2009
Hepatitis C virus (HCV) entry occurs via a pH- and clathrin-dependent endocytic pathway and requires a number of cellular factors, including CD81, the tight-junction proteins claudin 1 (CLDN1) and occludin, and scavenger receptor class B member I (SR-BI).
Balfe, Peter   +5 more
core   +2 more sources

Scavenger receptors in innate immunity

open access: yesCurrent Opinion in Immunology, 2002
Scavenger receptors (SR) are expressed by myeloid cells (macrophages and dendritic cells) and certain endothelial cells. They play an important role in uptake and clearance of effete components, such as modified host molecules and apoptotic cells.
Peiser, L, Mukhopadhyay, S, Gordon, S
openaire   +4 more sources

Physiological and pathogenic role of scavenger receptors in humans

open access: yesМедицинская иммунология, 2020
The scavenger receptors (SRs)) include > 30 different molecules structurally classified into 11 classes (A to L). They are expressed mostly on stromal macrophages, and their expression may be augmented in direct dependence with concentrations of their
E. Yu. Gusev   +3 more
doaj   +1 more source

The therapeutic potential of the filarial nematode-derived immunodulator, ES-62 in inflammatory disease [PDF]

open access: yes, 2010
The dramatic recent rise in the incidence of allergic or autoimmune inflammatory diseases in the West has been proposed to reflect the lack of appropriate priming of the immune response by infectious agents such as parasitic worms during childhood ...
Al-Riyami   +111 more
core   +2 more sources

Low CD36 and LOX-1 Levels and CD36 Gene Subexpression Are Associated with Metabolic Dysregulation in Older Individuals with Abdominal Obesity

open access: yesJournal of Diabetes Research, 2016
Background. Obesity study in the context of scavenger receptors has been linked to atherosclerosis. CD36 and LOX-1 are important, since they have been associated with atherogenic and metabolic disease but not fat redistribution.
Perla-Monserrat Madrigal-Ruíz   +9 more
doaj   +1 more source

Home - About - Disclaimer - Privacy