Results 31 to 40 of about 54,319 (245)
Innate scavenger receptor-A regulates adaptive T helper cell responses to pathogen infection
Nature Communications, 2017 Scavenger receptors can function as pattern recognition receptors to sense infection. Here the authors show that, in response to worm and bacterial infection, scavenger receptor class A prevents nuclear localization of IRF5 and thereby drives M2 ...
Zhipeng Xu +15 more
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Journal of Clinical and Translational Science, 2019 OBJECTIVES/SPECIFIC AIMS: Scavenger receptor (SR) surface proteins are highly conserved motifs and are implicated in the uptake of nanotherapies. Gold nanoparticles functionalized with DNAzymes (DzNP) represent a promising novel nanotherapy for lung ...
Cory Sylber +4 more
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Journal of Lipid Research, 2012 There is a tight relationship between fertility and changes in cholesterol metabolism during spermatogenesis. In the testis, class B scavenger receptors (SR-B) SR-BI, SR-BII, and LIMP II mediate the selective uptake of cholesterol esters from HDL, which ...
María Emilia Casado +8 more
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Macrophage Scavenger Receptor Class A [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2000 Abstract—In atherogenesis, elevated plasma levels of low density lipoprotein (LDL) lead to the chronic presence of LDL in the arterial wall. There, LDL is modified (eg, oxidized), and these modified lipoproteins activate endothelial cells, which attract circulating monocytes.
Winther, M.P.J. de +3 more
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Physiological and pathogenic role of scavenger receptors in humans
Медицинская иммунология, 2020 The scavenger receptors (SRs)) include > 30 different molecules structurally classified into 11 classes (A to L). They are expressed mostly on stromal macrophages, and their expression may be augmented in direct dependence with concentrations of their
E. Yu. Gusev +3 more
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Journal of Diabetes Research, 2016 Background. Obesity study in the context of scavenger receptors has been linked to atherosclerosis. CD36 and LOX-1 are important, since they have been associated with atherogenic and metabolic disease but not fat redistribution.
Perla-Monserrat Madrigal-Ruíz +9 more
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Scavenger receptors clear the air [PDF]
Journal of Clinical Investigation, 2007 Inhaled environmental oxidants, such as ozone and particulates, have been variably linked to epithelial injury, inflammation, and perturbations in lung development, growth, and function. Reactions between ozone and lung surface lipids likely account for exposure-related pathophysiologic sequelae. In this issue of the JCI, Dahl et al.
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Giant foam-like macrophages in advanced ovarian cancer
Сибирский онкологический журнал, 2022 Introduction. Ovarian cancer (OC) is the third most common gynecological cancer with the worst prognosis and highest mortality rate. The progression of OC can be accompanied by the detrimental functions of the components of the tumor microenvironment ...
M. A. Rakina +6 more
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Scavenger receptors: a key player in cardiovascular diseases
Biomolecular Concepts, 2012 The scavenger receptor (SR) super family consists of integral membrane glycoproteins that are involved in recognition of polyanionic structures of either endogenous (e.g., oxidized low-density lipoprotein) or exogenous (e.g., bacterial ...
Ashraf Mohammad Z., Sahu Anita
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PLoS Pathogens, 2009 Virtually all of the elements of Mycobacterium tuberculosis (Mtb) pathogenesis, including pro-inflammatory cytokine production, granuloma formation, cachexia, and mortality, can be induced by its predominant cell wall glycolipid, trehalose 6,6 ...
Dawn M E Bowdish +8 more
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