Results 21 to 30 of about 620,119 (261)
Curr Biol, 2020 Scavenger receptors (SRs) are a large family of cell-surface receptors that are diverse in their structure and biological function and are divided into different classes. SRs can bind to a range of ligands and enhance the elimination of altered-self or non-self targets.
Alquraini A, El Khoury J.
europepmc +4 more sources
The Evolution of the Scavenger Receptor Cysteine-Rich Domain of the Class A Scavenger Receptors [PDF]
Frontiers in Immunology, 2015 The class A Scavenger Receptor (cA-SR) family is a group of five evolutionarily related innate immune receptors. The cA-SRs are known for their promiscuous ligand binding; as they have been shown to bind bacteria such as Streptococcus pneumoniae, and ...
Nicholas eYap +3 more
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More Than Just a Removal Service: Scavenger Receptors in Leukocyte Trafficking [PDF]
Frontiers in Immunology, 2018 Scavenger receptors are a highly diverse superfamily of proteins which are grouped by their inherent ability to bind and internalize a wide array of structurally diverse ligands which can be either endogenous or exogenous in nature.
Daniel A. Patten, Shishir Shetty
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Standardizing Scavenger Receptor Nomenclature [PDF]
The Journal of Immunology, 2014 Abstract Scavenger receptors constitute a large family of proteins that are structurally diverse and participate in a wide range of biological functions. These receptors are expressed predominantly by myeloid cells and recognize a variety of ligands, including endogenous and modified host-derived molecules and microbial pathogens.
PrabhuDas, Mercy +14 more
openaire +5 more sources
International Journal of Hypertension, 2010 Scavenger receptors act as membrane-bound and soluble proteins that bind to macromolecular complexes and pathogens. This diverse supergroup of proteins mediates binding to modified lipoprotein particles which regulate the initiation and progression of ...
Sam L. Stephen +7 more
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Immunological Outcomes Mediated Upon Binding of Heat Shock Proteins to Scavenger Receptors SCARF1 and LOX-1, and Endocytosis by Mononuclear Phagocytes [PDF]
Frontiers in Immunology, 2020 Heat shock proteins (HSP) are a highly abundant class of molecular chaperones that can be released into the extracellular milieu and influence the immune response. HSP release can occur when cells undergo necrosis and exude their contents.
Ayesha Murshid +6 more
doaj +2 more sources
Scavenger receptors: key players in the immunological puzzle of lupus [PDF]
Frontiers in LupusScavenger receptors (SRs) play an important role in the innate immune response by recognizing and binding a variety of ligands to initiate the removal of both altered self- and non-self-antigens. Over the last two decades, SRs have become a forefront for
Sabine Hahn +4 more
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Journal of Lipid Research, 2005 Scavenger receptors were originally defined by their ability to bind and internalize modified lipoproteins. Macrophages express at least six structurally different cell surface receptors for modified forms of LDL that contribute to foam cell formation in
David R. Greaves, Siamon Gordon
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The Scavenger Function of LSECs, a Regulator of Liver Diseases [PDF]
Current Issues in Molecular BiologyLiver sinusoidal endothelial cells are highly specialized endothelial cells that contribute to liver homeostasis through their remarkable scavenger function.
Juntao Zhou +4 more
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Scavenger receptors: a key player in cardiovascular diseases
Biomolecular Concepts, 2012 The scavenger receptor (SR) super family consists of integral membrane glycoproteins that are involved in recognition of polyanionic structures of either endogenous (e.g., oxidized low-density lipoprotein) or exogenous (e.g., bacterial ...
Anita Sahu
exaly +2 more sources