Results 11 to 20 of about 620,119 (261)
Macrophage scavenger receptors: Tumor support and tumor inhibition [PDF]
Frontiers in Oncology, 2023 Tumor-associated macrophages (TAMs) are a heterogeneous population of myeloid cells that constitute up to 50% of the cell mass of human tumors. TAMs interact with the components of the tumor microenvironment (TME) by using scavenger receptors (SRs), a ...
Elena Kazakova +10 more
doaj +6 more sources
Scavenger Receptors and Atherosclerosis
Biological Research, 2000 Scavenger receptors were discovered as cell surface proteins capable of binding and internalization of modified lipoproteins. These receptors exhibit a broad ligand binding specificity including potential physiological and pathophysiological ligands ...
ATTILIO RIGOTTI
doaj +8 more sources
Targeting Scavenger Receptors in Inflammatory Disorders and Oxidative Stress [PDF]
Antioxidants, 2022 Oxidative stress and inflammation cannot be considered as diseases themselves; however, they are major risk factors for the development and progression of the pathogenesis underlying many illnesses, such as cancer, neurological disorders (including ...
Bonghee Lee +2 more
exaly +4 more sources
Alpha-Fetoprotein Binding Mucin and Scavenger Receptors: An Available Bio-Target for Treating Cancer [PDF]
Frontiers in Oncology, 2021 Alpha-fetoprotein (AFP) entrance into cancer cells is mediated by AFP receptors (AFPRs) and exerts malignant effects. Therefore, understanding the structure of AFPRs will facilitate the development of rational approaches for vaccine design, drug delivery,
Mingyue Zhu, Kun Liu, Bo Lin
exaly +4 more sources
Scavenger receptors in host defense: from functional aspects to mode of action [PDF]
Cell Communication and Signaling, 2022 Scavenger receptors belong to a superfamily of proteins that are structurally heterogeneous and encompass the miscellaneous group of transmembrane proteins and soluble secretory extracellular domain.
Qamar Taban +4 more
doaj +3 more sources
Scavenger Receptors as Biomarkers and Therapeutic Targets in Cardiovascular Disease [PDF]
Cells, 2020 The process of atherosclerosis leads to the formation of plaques in the arterial wall, resulting in a decreased blood supply to tissues and organs and its sequelae: morbidity and mortality.
Shervanthi Homer-Vanniasinkam +1 more
exaly +4 more sources
The evolution of the class A scavenger receptors [PDF]
BMC Evolutionary Biology, 2012 Background The class A scavenger receptors are a subclass of a diverse family of proteins defined based on their ability to bind modified lipoproteins. The 5 members of this family are strikingly variable in their protein structure and function, raising ...
Whelan Fiona J +4 more
doaj +6 more sources
Apoptotic cell recognition receptors and scavenger receptors [PDF]
Immunological Reviews, 2016 SummaryPhosphatidylserine recognition receptors are a highly diverse set of receptors grouped by their ability to recognize the ‘eat‐me’ signal phosphatidylserine on apoptotic cells. Most of the phosphatidylserine recognition receptors dampen inflammation by inducing the production of anti‐inflammatory mediators during the phagocytosis of apoptotic ...
Kodi Ravichandran, Kristen Penberthy
exaly +5 more sources
The Antimicrobial Peptide Cathelicidin Exerts Immunomodulatory Effects via Scavenger Receptors [PDF]
International Journal of Molecular Sciences, 2023 An active form of cathelicidin antimicrobial peptide, LL-37, has immunomodulatory and stimulatory effects, though the specific pathways are not clear.
Yoshihide Asano +2 more
exaly +3 more sources
Scavenger receptors in innate immunity
Current Opinion in Immunology, 2002 Scavenger receptors (SR) are expressed by myeloid cells (macrophages and dendritic cells) and certain endothelial cells. They play an important role in uptake and clearance of effete components, such as modified host molecules and apoptotic cells.
Siamon Gordon +2 more
exaly +5 more sources