Results 11 to 20 of about 98,327 (285)

A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease. [PDF]

J Immunol, 2017
Scavenger receptors constitute a large family of proteins that are structurally diverse and participate in a wide range of biological functions. These receptors are expressed predominantly by myeloid cells and recognize a diverse variety of ligands ...
PrabhuDas MR, Baldwin CL, Bollyky PL, Bowdish DME, Drickamer K, Febbraio M, Herz J, Kobzik L, Krieger M, Loike J, McVicker B, Means TK, Moestrup SK, Post SR, Sawamura T, Silverstein S, Speth RC, Telfer JC, Thiele GM, Wang XY, Wright SD, El Khoury J.   +21 more
europepmc   +3 more sources

Immunological Outcomes Mediated Upon Binding of Heat Shock Proteins to Scavenger Receptors SCARF1 and LOX-1, and Endocytosis by Mononuclear Phagocytes [PDF]

Frontiers in Immunology, 2020
Heat shock proteins (HSP) are a highly abundant class of molecular chaperones that can be released into the extracellular milieu and influence the immune response. HSP release can occur when cells undergo necrosis and exude their contents.
Ayesha Murshid, Thiago J. Borges, Thiago J. Borges, Cristina Bonorino, Cristina Bonorino, Benjamin J. Lang, Stuart K. Calderwood   +6 more
doaj   +2 more sources

Scavenger receptors: key players in the immunological puzzle of lupus [PDF]

Frontiers in Lupus
Scavenger receptors (SRs) play an important role in the innate immune response by recognizing and binding a variety of ligands to initiate the removal of both altered self- and non-self-antigens. Over the last two decades, SRs have become a forefront for
Sabine Hahn, Monika Chitre, Dominique Shepard, Romana Rashid, Zaida G. Ramirez-Ortiz   +4 more
doaj   +2 more sources

Lung macrophage scavenger receptor SR-A6 (MARCO) is an adenovirus type-specific virus entry receptor. [PDF]

PLoS Pathogens, 2018
Macrophages are a diverse group of phagocytic cells acting in host protection against stress, injury, and pathogens. Here, we show that the scavenger receptor SR-A6 is an entry receptor for human adenoviruses in murine alveolar macrophage-like MPI cells,
Nicole Stichling, Maarit Suomalainen, Justin W Flatt, Markus Schmid, Martin Pacesa, Silvio Hemmi, Wolfgang Jungraithmayr, Mareike D Maler, Marina A Freudenberg, Andreas Plückthun, Tobias May, Mario Köster, György Fejer, Urs F Greber   +13 more
doaj   +7 more sources

Identification of scavenger receptors and thrombospondin‐type‐1 repeat proteins potentially relevant for plastid recognition in Sacoglossa [PDF]

Ecology and Evolution, 2020
Functional kleptoplasty is a photosymbiotic relationship, in which photosynthetically active chloroplasts serve as an intracellular symbiont for a heterotrophic host.
Jenny Melo Clavijo, Silja Frankenbach, Cátia Fidalgo, João Serôdio, Alexander Donath, Angelika Preisfeld, Gregor Christa   +6 more
doaj   +2 more sources

Scavenger receptors in innate immunity

Current Opinion in Immunology, 2002
Scavenger receptors (SR) are expressed by myeloid cells (macrophages and dendritic cells) and certain endothelial cells. They play an important role in uptake and clearance of effete components, such as modified host molecules and apoptotic cells.
Subhankar Mukhopadhyay, Siamon Gordon
exaly   +4 more sources

Defective expression of scavenger receptors in celiac disease mucosa. [PDF]

PLoS ONE, 2014
Celiac disease (CD) is a gluten sensitive enteropathy characterized by a marked infiltration of the mucosa with immune cells, over-production of inflammatory cytokines and epithelial cell damage.
Maria Laura Cupi, Massimiliano Sarra, Daniela De Nitto, Eleonora Franzè, Irene Marafini, Ivan Monteleone, Giovanna Del Vecchio Blanco, Omero Alessandro Paoluzi, Davide Di Fusco, Paolo Gentileschi, Angela Ortenzi, Alfredo Colantoni, Francesco Pallone, Giovanni Monteleone   +13 more
doaj   +2 more sources

Signaling pathways required for macrophage scavenger receptor-mediated phagocytosis: analysis by scanning cytometry [PDF]

Respiratory Research, 2008
Background Scavenger receptors are important components of the innate immune system in the lung, allowing alveolar macrophages to bind and phagocytose numerous unopsonized targets.
Winkler Aaron R, DeLoid Glen, Imrich Amy, Sulahian Timothy H, Kobzik Lester   +4 more
doaj   +7 more sources

Platelet hyperreactivity, scavenger receptors and atherothrombosis [PDF]

Journal of Thrombosis and Haemostasis, 2009
Scavenger receptors (SRs) were initially identified as macrophage receptors that recognize modified lipoproteins. The lists of SRs, their ligands and cells expressing SRs have been significantly extended during the last two decades. What has become clear is that many ligands of SRs are present in vivo only in pathologic conditions.
M, Valiyaveettil, E A, Podrez
exaly   +3 more sources

Graphene Nanoflake Uptake Mediated by Scavenger Receptors [PDF]

Nano Letters, 2019
The biological interactions of graphene have been extensively investigated over the last 10 years. However, very little is known about graphene interactions with the cell surface and how the graphene internalization process is driven and mediated by specific recognition sites at the interface with the cell.
Valentina Castagnola, Luca Boselli, Margarita Esquivel-Gaon   +2 more
exaly   +6 more sources