Results 81 to 90 of about 59,530 (304)

Experiments and simulations on short chain fatty acid production in a colonic bacterial community [PDF]

, 2018
Understanding how production of specific metabolites by gut microbes is modulated by interactions with surrounding species and by environmental nutrient availability is an important open challenge in microbiome research.
Bobrow, Johanna, Dukovski, Ilija, Kong, David, Ostrinskaya, Alla, Segre, Daniel, Thorsen, Todd, Yu, Bea   +6 more
core   +1 more source

Intestine microbiota and SCFAs response in naturally Cryptosporidium-infected plateau yaks

Frontiers in Cellular and Infection Microbiology, 2023
Diarrhea is a severe bovine disease, globally prevalent in farm animals with a decrease in milk production and a low fertility rate. Cryptosporidium spp. are important zoonotic agents of bovine diarrhea. However, little is known about microbiota and short-chain fatty acids (SCFAs) changes in yaks infected with Cryptosporidium spp.
Hailong Dong, Xiushuang Chen, Xiushuang Chen, Xiaoxiao Zhao, Xiaoxiao Zhao, Chenxi Zhao, Chenxi Zhao, Khalid Mehmood, Muhammad Fakhar-e-Alam Kulyar, Zeeshan Ahmad Bhutta, Jiangyong Zeng, Shah Nawaz, Qingxia Wu, Kun Li, Kun Li   +14 more
openaire   +3 more sources

Ultrasound‐Responsive Engineered Bacteria for Targeted Cancer Therapy: Strategies, Mechanisms, and Applications

Advanced Science, EarlyView.
This review elucidates URB design strategies, including genetic and physicochemical modifications, while dissecting the synergistic mechanisms governing spatiotemporal control. It further evaluates applications in targeted drug delivery, gene modulation, and immunotherapy, finally offering perspectives on overcoming translational barriers for clinical ...
Xueyao Wang, Wenjing Xu, Yafang Lu, Huaibin Yu, Zhengbao Zha, Xijun Zhang   +5 more
wiley   +1 more source

Tractable approximate deduction for OWL [PDF]

, 2016
Acknowledgements This work has been partially supported by the European project Marrying Ontologies and Software Technologies (EU ICT2008-216691), the European project Knowledge Driven Data Exploitation (EU FP7/IAPP2011-286348), the UK EPSRC project ...
Pan, Jeff Z., Ren, Yuan, Zhao, Yuting
core   +1 more source

Constraint of Lignin–Carbohydrate Complex Orchestrated on Polyphenol in Oil–Water Interface Targeting Ulcerative Colitis Therapy

Advanced Science, EarlyView.
This study constructed the W1/O/W2 emulsion–based targeted therapy delivery system for ulcerative colitis (UC) utilizing LCC as surfactant for the first time. This multifunctional emulsion offered certain therapeutic advantages for UC, including targeted colonic delivery of active compounds, synergistic modulation of gut microbiota through combined ...
Qian Wu, Xingyu Zhang, Jingjia Zhang, Gaohui Huang, Chen Zhou, Chunlin Li, Xiaojun Huang, Jianbo Xiao, Nianjie Feng, Yuanbin She   +9 more
wiley   +1 more source

Optimization of cholesterol removal, growth and fermentation patterns of Lactobacillus acidophilus ATCC 4962 in the presence of mannitol, fructo-oligosaccharide and inulin: a response surface methodology approach [PDF]

, 2005
Aims: To optimize cholesterol removal by Lactobacillus acidophilus ATCC 4962 in the presence of prebiotics, and study the growth and fermentation patterns of the prebiotics.
Liong, Min Tze, Shah, Nagendra P
core   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Effect of COVID-19 on the Gut Microbiota of Pregnant Women (review)

Эпидемиология и вакцинопрофилактика
The Novel coronavirus infection (COVID-19) pandemic has shown that pregnant women are at risk for infection and severe COVID- 19. Pregnant women often experience gastrointestinal symptoms both during the peak of the disease and within 90 days after ...
B. O. Bembeeva, T. V. Priputnevich, N. V. Dolgushina   +2 more
doaj   +1 more source

Decreased microbial co-occurrence network stability and SCFA receptor level correlates with obesity in African-origin women. [PDF]

, 2018
We compared the gut microbial populations in 100 women, from rural Ghana and urban US [50% lean (BMI < 25 kg/m2) and 50% obese (BMI ≥ 30 kg/m2)] to examine the ecological co-occurrence network topology of the gut microbiota as well as the relationship
Bernabé, Beatriz Peñalver, Brown, Laquita, Dong, Qunfeng, Dugas, Lara R, Fei, Na, Gao, Xiang, Gilbert, Jack A, Gottel, Neil, Kliethermes, Stephanie, Layden, Brian T, Luke, Amy, Nelson, David, Park, Seo Jin, Plange-Rhule, Jacob, Priyadarshini, Medha, Sun, Jun, Toh, Evelyn C   +16 more
core   +3 more sources

SCFAs Induce Mouse Neutrophil Chemotaxis through the GPR43 Receptor

PLoS ONE, 2011
Short chain fatty acids (SCFAs) have recently attracted attention as potential mediators of the effects of gut microbiota on intestinal inflammation. Some of these effects have been suggested to occur through the direct actions of SCFAs on the GPR43 receptor in neutrophils, though the precise role of this receptor in neutrophil activation is still ...
Marco A R Vinolo, G John Ferguson, Suhasini Kulkarni, George Damoulakis, Karen Anderson, Mohammad Bohlooly-Y, Len Stephens, Phillip T Hawkins, Rui Curi   +8 more
openaire   +4 more sources